| Full name: nucleolar complex associated 4 homolog | Alias Symbol: MGC3162|NET49|UTP19|Noc4 | ||
| Type: protein-coding gene | Cytoband: 12q24.33 | ||
| Entrez ID: 79050 | HGNC ID: HGNC:28461 | Ensembl Gene: ENSG00000184967 | OMIM ID: 612819 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NOC4L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOC4L | 79050 | 218860_at | 0.6471 | 0.0567 | |
| GSE20347 | NOC4L | 79050 | 218860_at | 0.1617 | 0.1796 | |
| GSE23400 | NOC4L | 79050 | 218860_at | 0.1599 | 0.0009 | |
| GSE26886 | NOC4L | 79050 | 218860_at | 1.2745 | 0.0000 | |
| GSE29001 | NOC4L | 79050 | 218860_at | 0.4550 | 0.0519 | |
| GSE38129 | NOC4L | 79050 | 218860_at | 0.3331 | 0.0014 | |
| GSE45670 | NOC4L | 79050 | 218860_at | 0.4906 | 0.0000 | |
| GSE53622 | NOC4L | 79050 | 83566 | 0.4386 | 0.0000 | |
| GSE53624 | NOC4L | 79050 | 83566 | 0.8888 | 0.0000 | |
| GSE63941 | NOC4L | 79050 | 218860_at | 0.4933 | 0.0290 | |
| GSE77861 | NOC4L | 79050 | 218860_at | 0.3338 | 0.0632 | |
| GSE97050 | NOC4L | 79050 | A_33_P3394828 | 0.1708 | 0.5552 | |
| SRP007169 | NOC4L | 79050 | RNAseq | 1.2306 | 0.1002 | |
| SRP064894 | NOC4L | 79050 | RNAseq | 0.7034 | 0.0094 | |
| SRP133303 | NOC4L | 79050 | RNAseq | 0.3171 | 0.2020 | |
| SRP159526 | NOC4L | 79050 | RNAseq | 0.4781 | 0.0960 | |
| SRP193095 | NOC4L | 79050 | RNAseq | 0.5126 | 0.0000 | |
| SRP219564 | NOC4L | 79050 | RNAseq | 0.3620 | 0.3255 | |
| TCGA | NOC4L | 79050 | RNAseq | 0.2071 | 0.0008 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NOC4L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NOC4L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOC4L | 79050 | 4 | 5 | 21 | |
| GSE20123 | NOC4L | 79050 | 4 | 5 | 21 | |
| GSE43470 | NOC4L | 79050 | 3 | 3 | 37 | |
| GSE46452 | NOC4L | 79050 | 8 | 3 | 48 | |
| GSE47630 | NOC4L | 79050 | 9 | 3 | 28 | |
| GSE54993 | NOC4L | 79050 | 0 | 6 | 64 | |
| GSE54994 | NOC4L | 79050 | 4 | 8 | 41 | |
| GSE60625 | NOC4L | 79050 | 0 | 0 | 11 | |
| GSE74703 | NOC4L | 79050 | 2 | 3 | 31 | |
| GSE74704 | NOC4L | 79050 | 2 | 3 | 15 | |
| TCGA | NOC4L | 79050 | 22 | 15 | 59 |
Total number of gains: 58; Total number of losses: 54; Total Number of normals: 376.
Somatic mutations of NOC4L:
Generating mutation plots.
Highly correlated genes for NOC4L:
Showing top 20/767 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOC4L | CPAMD8 | 0.742023 | 3 | 0 | 3 |
| NOC4L | SLC34A1 | 0.729264 | 3 | 0 | 3 |
| NOC4L | C19orf25 | 0.725833 | 3 | 0 | 3 |
| NOC4L | WRAP73 | 0.721925 | 5 | 0 | 4 |
| NOC4L | MBD6 | 0.718416 | 3 | 0 | 3 |
| NOC4L | BRPF1 | 0.713808 | 3 | 0 | 3 |
| NOC4L | BOP1 | 0.711107 | 3 | 0 | 3 |
| NOC4L | STMN3 | 0.709956 | 3 | 0 | 3 |
| NOC4L | ENGASE | 0.708247 | 3 | 0 | 3 |
| NOC4L | TOE1 | 0.70639 | 5 | 0 | 4 |
| NOC4L | BLACAT1 | 0.705508 | 3 | 0 | 3 |
| NOC4L | ZNF511 | 0.701333 | 4 | 0 | 3 |
| NOC4L | SH2D5 | 0.701303 | 6 | 0 | 6 |
| NOC4L | TIMMDC1 | 0.698938 | 3 | 0 | 3 |
| NOC4L | TOX2 | 0.698609 | 3 | 0 | 3 |
| NOC4L | GPR180 | 0.698349 | 4 | 0 | 4 |
| NOC4L | ZAP70 | 0.697266 | 3 | 0 | 3 |
| NOC4L | TCF7 | 0.696766 | 4 | 0 | 3 |
| NOC4L | COL4A2 | 0.693008 | 3 | 0 | 3 |
| NOC4L | ABCC10 | 0.691897 | 4 | 0 | 3 |
For details and further investigation, click here
