| Full name: mediator complex subunit 20 | Alias Symbol: DKFZp586D2223|PRO0213|SRB2 | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 9477 | HGNC ID: HGNC:16840 | Ensembl Gene: ENSG00000124641 | OMIM ID: 612915 |
| Drug and gene relationship at DGIdb | |||
Expression of MED20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MED20 | 9477 | 212872_s_at | 0.7831 | 0.0289 | |
| GSE20347 | MED20 | 9477 | 212872_s_at | 0.4711 | 0.0033 | |
| GSE23400 | MED20 | 9477 | 212872_s_at | 0.3202 | 0.0000 | |
| GSE26886 | MED20 | 9477 | 212872_s_at | -0.0875 | 0.4763 | |
| GSE29001 | MED20 | 9477 | 212872_s_at | 0.3693 | 0.0393 | |
| GSE38129 | MED20 | 9477 | 212872_s_at | 0.5803 | 0.0000 | |
| GSE45670 | MED20 | 9477 | 212872_s_at | 0.6960 | 0.0000 | |
| GSE53622 | MED20 | 9477 | 93716 | 0.6049 | 0.0000 | |
| GSE53624 | MED20 | 9477 | 142856 | 0.9459 | 0.0000 | |
| GSE63941 | MED20 | 9477 | 212872_s_at | -0.4384 | 0.3918 | |
| GSE77861 | MED20 | 9477 | 212872_s_at | 0.1899 | 0.4488 | |
| GSE97050 | MED20 | 9477 | A_33_P3253528 | 0.1581 | 0.4929 | |
| SRP007169 | MED20 | 9477 | RNAseq | 0.0203 | 0.9636 | |
| SRP008496 | MED20 | 9477 | RNAseq | 0.1660 | 0.5655 | |
| SRP064894 | MED20 | 9477 | RNAseq | 0.3052 | 0.0341 | |
| SRP133303 | MED20 | 9477 | RNAseq | 0.5845 | 0.0000 | |
| SRP159526 | MED20 | 9477 | RNAseq | 0.6409 | 0.0017 | |
| SRP193095 | MED20 | 9477 | RNAseq | 0.2516 | 0.0207 | |
| SRP219564 | MED20 | 9477 | RNAseq | 0.2411 | 0.3610 | |
| TCGA | MED20 | 9477 | RNAseq | 0.1754 | 0.0025 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MED20 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MED20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MED20 | 9477 | 6 | 1 | 23 | |
| GSE20123 | MED20 | 9477 | 6 | 1 | 23 | |
| GSE43470 | MED20 | 9477 | 6 | 0 | 37 | |
| GSE46452 | MED20 | 9477 | 2 | 9 | 48 | |
| GSE47630 | MED20 | 9477 | 8 | 4 | 28 | |
| GSE54993 | MED20 | 9477 | 3 | 2 | 65 | |
| GSE54994 | MED20 | 9477 | 11 | 4 | 38 | |
| GSE60625 | MED20 | 9477 | 0 | 1 | 10 | |
| GSE74703 | MED20 | 9477 | 6 | 0 | 30 | |
| GSE74704 | MED20 | 9477 | 3 | 1 | 16 | |
| TCGA | MED20 | 9477 | 20 | 13 | 63 |
Total number of gains: 71; Total number of losses: 36; Total Number of normals: 381.
Somatic mutations of MED20:
Generating mutation plots.
Highly correlated genes for MED20:
Showing top 20/445 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MED20 | HOXC9 | 0.790838 | 3 | 0 | 3 |
| MED20 | GPR180 | 0.733466 | 4 | 0 | 4 |
| MED20 | TNFAIP8L1 | 0.719814 | 4 | 0 | 4 |
| MED20 | LRWD1 | 0.689096 | 3 | 0 | 3 |
| MED20 | TPX2 | 0.684527 | 9 | 0 | 9 |
| MED20 | XPO5 | 0.679743 | 6 | 0 | 5 |
| MED20 | POC1A | 0.677189 | 6 | 0 | 6 |
| MED20 | CDCA5 | 0.675343 | 6 | 0 | 5 |
| MED20 | BEND3 | 0.675136 | 5 | 0 | 5 |
| MED20 | CDC6 | 0.674927 | 8 | 0 | 8 |
| MED20 | LRR1 | 0.673693 | 6 | 0 | 6 |
| MED20 | RUVBL1 | 0.673546 | 8 | 0 | 8 |
| MED20 | USB1 | 0.673312 | 6 | 0 | 6 |
| MED20 | GPRIN1 | 0.671774 | 4 | 0 | 4 |
| MED20 | KIF4A | 0.669248 | 10 | 0 | 10 |
| MED20 | CKS1B | 0.668453 | 9 | 0 | 8 |
| MED20 | SKA3 | 0.667927 | 5 | 0 | 5 |
| MED20 | UBE2T | 0.665142 | 5 | 0 | 4 |
| MED20 | EXO1 | 0.665142 | 11 | 0 | 10 |
| MED20 | RCOR2 | 0.665045 | 3 | 0 | 3 |
For details and further investigation, click here
