FLAD1

 

Full name: flavin adenine dinucleotide synthetase 1 Alias Symbol: PP591|FAD1
Type: protein-coding gene Cytoband: 1q21.3
Entrez ID: 80308 HGNC ID: HGNC:24671 Ensembl Gene: ENSG00000160688 OMIM ID: 610595
Drug and gene relationship at DGIdb

 

Expression of FLAD1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FLAD1 80308 212541_at 1.1272 0.0156
GSE20347 FLAD1 80308 212541_at 0.6682 0.0000
GSE23400 FLAD1 80308 212541_at 0.5624 0.0000
GSE26886 FLAD1 80308 212541_at 0.7753 0.0080
GSE29001 FLAD1 80308 212541_at 0.5660 0.0171
GSE38129 FLAD1 80308 212541_at 0.7594 0.0000
GSE45670 FLAD1 80308 212541_at 0.6589 0.0005
GSE53622 FLAD1 80308 54302 0.5328 0.0000
GSE53624 FLAD1 80308 54302 0.4793 0.0000
GSE63941 FLAD1 80308 212541_at 1.0567 0.0031
GSE77861 FLAD1 80308 212541_at 1.0078 0.0018
GSE97050 FLAD1 80308 A_23_P34527 0.2416 0.4977
SRP007169 FLAD1 80308 RNAseq 0.1916 0.5525
SRP008496 FLAD1 80308 RNAseq 0.7595 0.0035
SRP064894 FLAD1 80308 RNAseq 0.7187 0.0011
SRP133303 FLAD1 80308 RNAseq 0.6666 0.0000
SRP159526 FLAD1 80308 RNAseq 1.0985 0.0000
SRP193095 FLAD1 80308 RNAseq 0.6418 0.0000
SRP219564 FLAD1 80308 RNAseq 0.6706 0.1083
TCGA FLAD1 80308 RNAseq 0.2856 0.0000

Upregulated datasets: 4; Downregulated datasets: 0.  

 

Survival by FLAD1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of FLAD1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FLAD1 80308 14 0 16
GSE20123 FLAD1 80308 13 0 17
GSE43470 FLAD1 80308 6 2 35
GSE46452 FLAD1 80308 2 1 56
GSE47630 FLAD1 80308 14 0 26
GSE54993 FLAD1 80308 0 4 66
GSE54994 FLAD1 80308 16 0 37
GSE60625 FLAD1 80308 0 0 11
GSE74703 FLAD1 80308 6 1 29
GSE74704 FLAD1 80308 6 0 14
TCGA FLAD1 80308 38 2 56

Total number of gains: 115; Total number of losses: 10; Total Number of normals: 363.  

 

Somatic mutations of FLAD1:

 

Generating mutation plots.

 

Highly correlated genes for FLAD1:

 

Showing top 20/796 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FLAD1FEN10.759707707
FLAD1BEND30.753493707
FLAD1KLHL260.744723303
FLAD1DDX39A0.73654611011
FLAD1IPO90.734675909
FLAD1DAP30.73178511010
FLAD1GPR1800.729478303
FLAD1BOP10.726291303
FLAD1PGP0.720316505
FLAD1CCDC860.718592707
FLAD1KIF4A0.7175411010
FLAD1TPX20.71750210010
FLAD1AK80.714663303
FLAD1B4GALNT30.712628404
FLAD1BRPF10.711439303
FLAD1POLR1A0.711236404
FLAD1KPNA20.70991706
FLAD1CCT30.70589511010
FLAD1NEK20.70236110010
FLAD1IMP40.69794911011

For details and further investigation, click here