| Full name: RNA binding motif protein 28 | Alias Symbol: FLJ10377 | ||
| Type: protein-coding gene | Cytoband: 7q32.1 | ||
| Entrez ID: 55131 | HGNC ID: HGNC:21863 | Ensembl Gene: ENSG00000106344 | OMIM ID: 612074 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RBM28:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RBM28 | 55131 | 218593_at | 0.5988 | 0.1155 | |
| GSE20347 | RBM28 | 55131 | 218593_at | 0.9140 | 0.0000 | |
| GSE23400 | RBM28 | 55131 | 218593_at | 0.7929 | 0.0000 | |
| GSE26886 | RBM28 | 55131 | 218593_at | 0.7100 | 0.0005 | |
| GSE29001 | RBM28 | 55131 | 218593_at | 0.8931 | 0.0004 | |
| GSE38129 | RBM28 | 55131 | 218593_at | 0.9334 | 0.0000 | |
| GSE45670 | RBM28 | 55131 | 218593_at | 0.5790 | 0.0034 | |
| GSE53622 | RBM28 | 55131 | 61771 | 0.4916 | 0.0000 | |
| GSE53624 | RBM28 | 55131 | 61771 | 0.3823 | 0.0000 | |
| GSE63941 | RBM28 | 55131 | 218593_at | -0.0803 | 0.8913 | |
| GSE77861 | RBM28 | 55131 | 218593_at | 0.5309 | 0.0042 | |
| GSE97050 | RBM28 | 55131 | A_23_P168629 | 0.2162 | 0.3404 | |
| SRP007169 | RBM28 | 55131 | RNAseq | 1.5000 | 0.0005 | |
| SRP008496 | RBM28 | 55131 | RNAseq | 1.2160 | 0.0003 | |
| SRP064894 | RBM28 | 55131 | RNAseq | 0.5955 | 0.0006 | |
| SRP133303 | RBM28 | 55131 | RNAseq | 0.3772 | 0.0009 | |
| SRP159526 | RBM28 | 55131 | RNAseq | 0.4931 | 0.0145 | |
| SRP193095 | RBM28 | 55131 | RNAseq | 0.4068 | 0.0011 | |
| SRP219564 | RBM28 | 55131 | RNAseq | -0.1065 | 0.6014 | |
| TCGA | RBM28 | 55131 | RNAseq | 0.1123 | 0.0560 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by RBM28 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RBM28:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RBM28 | 55131 | 8 | 1 | 21 | |
| GSE20123 | RBM28 | 55131 | 8 | 2 | 20 | |
| GSE43470 | RBM28 | 55131 | 2 | 3 | 38 | |
| GSE46452 | RBM28 | 55131 | 7 | 2 | 50 | |
| GSE47630 | RBM28 | 55131 | 7 | 4 | 29 | |
| GSE54993 | RBM28 | 55131 | 3 | 5 | 62 | |
| GSE54994 | RBM28 | 55131 | 6 | 11 | 36 | |
| GSE60625 | RBM28 | 55131 | 0 | 0 | 11 | |
| GSE74703 | RBM28 | 55131 | 2 | 3 | 31 | |
| GSE74704 | RBM28 | 55131 | 4 | 2 | 14 | |
| TCGA | RBM28 | 55131 | 28 | 22 | 46 |
Total number of gains: 75; Total number of losses: 55; Total Number of normals: 358.
Somatic mutations of RBM28:
Generating mutation plots.
Highly correlated genes for RBM28:
Showing top 20/607 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RBM28 | WDR83 | 0.780624 | 3 | 0 | 3 |
| RBM28 | RAX2 | 0.778053 | 3 | 0 | 3 |
| RBM28 | GNPNAT1 | 0.775741 | 3 | 0 | 3 |
| RBM28 | SOX30 | 0.773948 | 3 | 0 | 3 |
| RBM28 | SIM1 | 0.772867 | 3 | 0 | 3 |
| RBM28 | MBD6 | 0.763433 | 3 | 0 | 3 |
| RBM28 | SLC25A53 | 0.756563 | 3 | 0 | 3 |
| RBM28 | ZNF777 | 0.755508 | 4 | 0 | 4 |
| RBM28 | ZDHHC8 | 0.753618 | 3 | 0 | 3 |
| RBM28 | BEND3 | 0.750659 | 6 | 0 | 5 |
| RBM28 | PUS1 | 0.748719 | 9 | 0 | 9 |
| RBM28 | SLC6A3 | 0.747406 | 3 | 0 | 3 |
| RBM28 | KIF4A | 0.745976 | 8 | 0 | 8 |
| RBM28 | METTL2B | 0.745104 | 3 | 0 | 3 |
| RBM28 | MTERF3 | 0.742642 | 8 | 0 | 8 |
| RBM28 | TPX2 | 0.736173 | 7 | 0 | 7 |
| RBM28 | C19orf44 | 0.732808 | 4 | 0 | 4 |
| RBM28 | CXorf38 | 0.729594 | 4 | 0 | 3 |
| RBM28 | CMSS1 | 0.729038 | 4 | 0 | 4 |
| RBM28 | RUVBL1 | 0.729002 | 8 | 0 | 8 |
For details and further investigation, click here
