| Full name: protocadherin 1 | Alias Symbol: pc42 | ||
| Type: protein-coding gene | Cytoband: 5q31.3 | ||
| Entrez ID: 5097 | HGNC ID: HGNC:8655 | Ensembl Gene: ENSG00000156453 | OMIM ID: 603626 |
| Drug and gene relationship at DGIdb | |||
Expression of PCDH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCDH1 | 5097 | 203918_at | -1.0419 | 0.0510 | |
| GSE20347 | PCDH1 | 5097 | 203918_at | -0.7826 | 0.0000 | |
| GSE23400 | PCDH1 | 5097 | 203918_at | -0.8050 | 0.0000 | |
| GSE26886 | PCDH1 | 5097 | 203918_at | -0.4987 | 0.0030 | |
| GSE29001 | PCDH1 | 5097 | 203918_at | -0.8372 | 0.0010 | |
| GSE38129 | PCDH1 | 5097 | 203918_at | -0.7221 | 0.0000 | |
| GSE45670 | PCDH1 | 5097 | 203918_at | -0.0969 | 0.5292 | |
| GSE53622 | PCDH1 | 5097 | 14286 | -1.7708 | 0.0000 | |
| GSE53624 | PCDH1 | 5097 | 14286 | -1.8136 | 0.0000 | |
| GSE63941 | PCDH1 | 5097 | 203918_at | 0.6064 | 0.2347 | |
| GSE77861 | PCDH1 | 5097 | 203918_at | -0.2935 | 0.2747 | |
| GSE97050 | PCDH1 | 5097 | A_24_P234838 | -0.1124 | 0.6238 | |
| SRP007169 | PCDH1 | 5097 | RNAseq | -2.5627 | 0.0001 | |
| SRP008496 | PCDH1 | 5097 | RNAseq | -2.8339 | 0.0000 | |
| SRP064894 | PCDH1 | 5097 | RNAseq | -2.0568 | 0.0000 | |
| SRP133303 | PCDH1 | 5097 | RNAseq | -2.2216 | 0.0000 | |
| SRP159526 | PCDH1 | 5097 | RNAseq | -2.1543 | 0.0000 | |
| SRP193095 | PCDH1 | 5097 | RNAseq | -1.6897 | 0.0000 | |
| SRP219564 | PCDH1 | 5097 | RNAseq | -2.0164 | 0.0000 | |
| TCGA | PCDH1 | 5097 | RNAseq | -0.5518 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by PCDH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PCDH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCDH1 | 5097 | 2 | 11 | 17 | |
| GSE20123 | PCDH1 | 5097 | 2 | 11 | 17 | |
| GSE43470 | PCDH1 | 5097 | 2 | 10 | 31 | |
| GSE46452 | PCDH1 | 5097 | 0 | 27 | 32 | |
| GSE47630 | PCDH1 | 5097 | 1 | 19 | 20 | |
| GSE54993 | PCDH1 | 5097 | 9 | 1 | 60 | |
| GSE54994 | PCDH1 | 5097 | 2 | 14 | 37 | |
| GSE60625 | PCDH1 | 5097 | 0 | 0 | 11 | |
| GSE74703 | PCDH1 | 5097 | 2 | 7 | 27 | |
| GSE74704 | PCDH1 | 5097 | 2 | 5 | 13 | |
| TCGA | PCDH1 | 5097 | 3 | 38 | 55 |
Total number of gains: 25; Total number of losses: 143; Total Number of normals: 320.
Somatic mutations of PCDH1:
Generating mutation plots.
Highly correlated genes for PCDH1:
Showing top 20/1014 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCDH1 | DUSP15 | 0.821247 | 3 | 0 | 3 |
| PCDH1 | OR10G8 | 0.817397 | 3 | 0 | 3 |
| PCDH1 | DCD | 0.814003 | 3 | 0 | 3 |
| PCDH1 | PRSS3 | 0.80509 | 9 | 0 | 9 |
| PCDH1 | HOPX | 0.791027 | 9 | 0 | 9 |
| PCDH1 | PTK6 | 0.787909 | 12 | 0 | 12 |
| PCDH1 | TEN1 | 0.787663 | 3 | 0 | 3 |
| PCDH1 | MFSD2B | 0.780051 | 3 | 0 | 3 |
| PCDH1 | KRTAP20-1 | 0.775932 | 3 | 0 | 3 |
| PCDH1 | MUC22 | 0.77528 | 3 | 0 | 3 |
| PCDH1 | MAPK3 | 0.77299 | 10 | 0 | 10 |
| PCDH1 | LRFN2 | 0.772695 | 3 | 0 | 3 |
| PCDH1 | TGM1 | 0.77086 | 10 | 0 | 10 |
| PCDH1 | SMIM5 | 0.765483 | 7 | 0 | 7 |
| PCDH1 | EPS8L2 | 0.76144 | 12 | 0 | 12 |
| PCDH1 | EPS8L1 | 0.761377 | 11 | 0 | 10 |
| PCDH1 | NCCRP1 | 0.75933 | 3 | 0 | 3 |
| PCDH1 | KLHL10 | 0.758786 | 4 | 0 | 4 |
| PCDH1 | ABLIM3 | 0.758776 | 11 | 0 | 11 |
| PCDH1 | FLG | 0.757403 | 9 | 0 | 9 |
For details and further investigation, click here
