| Full name: G protein-coupled receptor 63 | Alias Symbol: PSP24(beta)|PSP24B | ||
| Type: protein-coding gene | Cytoband: 6q16.1 | ||
| Entrez ID: 81491 | HGNC ID: HGNC:13302 | Ensembl Gene: ENSG00000112218 | OMIM ID: 606915 |
| Drug and gene relationship at DGIdb | |||
Expression of GPR63:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPR63 | 81491 | 220993_s_at | 0.0658 | 0.7894 | |
| GSE20347 | GPR63 | 81491 | 220993_s_at | 0.1023 | 0.1451 | |
| GSE23400 | GPR63 | 81491 | 220993_s_at | 0.0080 | 0.8286 | |
| GSE26886 | GPR63 | 81491 | 220993_s_at | 0.3305 | 0.1865 | |
| GSE29001 | GPR63 | 81491 | 220993_s_at | 0.1762 | 0.3856 | |
| GSE38129 | GPR63 | 81491 | 220993_s_at | 0.0843 | 0.2066 | |
| GSE45670 | GPR63 | 81491 | 220993_s_at | 0.1126 | 0.3839 | |
| GSE53622 | GPR63 | 81491 | 44845 | 0.0326 | 0.8534 | |
| GSE53624 | GPR63 | 81491 | 44845 | 0.0906 | 0.5231 | |
| GSE63941 | GPR63 | 81491 | 220993_s_at | -1.3918 | 0.0050 | |
| GSE77861 | GPR63 | 81491 | 220993_s_at | 0.0254 | 0.7803 | |
| GSE97050 | GPR63 | 81491 | A_23_P214727 | 0.1354 | 0.5078 | |
| SRP007169 | GPR63 | 81491 | RNAseq | 1.8790 | 0.0749 | |
| SRP064894 | GPR63 | 81491 | RNAseq | -0.5174 | 0.0854 | |
| SRP133303 | GPR63 | 81491 | RNAseq | 0.1013 | 0.6717 | |
| SRP159526 | GPR63 | 81491 | RNAseq | 0.3496 | 0.3057 | |
| SRP193095 | GPR63 | 81491 | RNAseq | -0.0857 | 0.6795 | |
| SRP219564 | GPR63 | 81491 | RNAseq | -0.4084 | 0.4661 | |
| TCGA | GPR63 | 81491 | RNAseq | 0.0111 | 0.9705 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by GPR63 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR63:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR63 | 81491 | 1 | 3 | 26 | |
| GSE20123 | GPR63 | 81491 | 1 | 2 | 27 | |
| GSE43470 | GPR63 | 81491 | 3 | 2 | 38 | |
| GSE46452 | GPR63 | 81491 | 2 | 11 | 46 | |
| GSE47630 | GPR63 | 81491 | 8 | 6 | 26 | |
| GSE54993 | GPR63 | 81491 | 3 | 2 | 65 | |
| GSE54994 | GPR63 | 81491 | 8 | 8 | 37 | |
| GSE60625 | GPR63 | 81491 | 0 | 1 | 10 | |
| GSE74703 | GPR63 | 81491 | 2 | 2 | 32 | |
| GSE74704 | GPR63 | 81491 | 0 | 0 | 20 | |
| TCGA | GPR63 | 81491 | 4 | 25 | 67 |
Total number of gains: 32; Total number of losses: 62; Total Number of normals: 394.
Somatic mutations of GPR63:
Generating mutation plots.
Highly correlated genes for GPR63:
Showing top 20/55 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR63 | FAM155A | 0.700437 | 3 | 0 | 3 |
| GPR63 | CCND3 | 0.601798 | 3 | 0 | 3 |
| GPR63 | APBB1IP | 0.600111 | 3 | 0 | 3 |
| GPR63 | TFDP3 | 0.598491 | 4 | 0 | 4 |
| GPR63 | IL1RAPL2 | 0.598298 | 3 | 0 | 3 |
| GPR63 | PWP1 | 0.597369 | 3 | 0 | 3 |
| GPR63 | RNF113A | 0.589818 | 3 | 0 | 3 |
| GPR63 | SPCS3 | 0.588576 | 4 | 0 | 3 |
| GPR63 | MARCKSL1 | 0.587459 | 3 | 0 | 3 |
| GPR63 | CT55 | 0.585849 | 3 | 0 | 3 |
| GPR63 | CORO7 | 0.583896 | 3 | 0 | 3 |
| GPR63 | CST4 | 0.582044 | 3 | 0 | 3 |
| GPR63 | NDE1 | 0.580535 | 4 | 0 | 3 |
| GPR63 | EYA4 | 0.57897 | 3 | 0 | 3 |
| GPR63 | PGAP1 | 0.578873 | 3 | 0 | 3 |
| GPR63 | SH3KBP1 | 0.578828 | 3 | 0 | 3 |
| GPR63 | SEC11C | 0.573636 | 4 | 0 | 3 |
| GPR63 | CCSER1 | 0.573555 | 3 | 0 | 3 |
| GPR63 | EVI2B | 0.572524 | 3 | 0 | 3 |
| GPR63 | RARS2 | 0.569528 | 3 | 0 | 3 |
For details and further investigation, click here
