| Full name: amyloid beta precursor protein binding family B member 1 interacting protein | Alias Symbol: INAG1|RIAM | ||
| Type: protein-coding gene | Cytoband: 10p12.1 | ||
| Entrez ID: 54518 | HGNC ID: HGNC:17379 | Ensembl Gene: ENSG00000077420 | OMIM ID: 609036 |
| Drug and gene relationship at DGIdb | |||
APBB1IP involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04015 | Rap1 signaling pathway | |
| hsa04611 | Platelet activation |
Expression of APBB1IP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | APBB1IP | 54518 | 230925_at | 0.2476 | 0.8523 | |
| GSE20347 | APBB1IP | 54518 | 219994_at | -0.0368 | 0.5665 | |
| GSE23400 | APBB1IP | 54518 | 219994_at | -0.1097 | 0.0001 | |
| GSE26886 | APBB1IP | 54518 | 230925_at | 0.2095 | 0.5655 | |
| GSE29001 | APBB1IP | 54518 | 219994_at | -0.2022 | 0.1465 | |
| GSE38129 | APBB1IP | 54518 | 219994_at | -0.0986 | 0.0566 | |
| GSE45670 | APBB1IP | 54518 | 230925_at | -0.5574 | 0.0327 | |
| GSE53622 | APBB1IP | 54518 | 14943 | -0.3595 | 0.0078 | |
| GSE53624 | APBB1IP | 54518 | 14943 | -0.7452 | 0.0000 | |
| GSE63941 | APBB1IP | 54518 | 230925_at | -2.5749 | 0.0007 | |
| GSE77861 | APBB1IP | 54518 | 230925_at | -0.1656 | 0.2987 | |
| GSE97050 | APBB1IP | 54518 | A_24_P232365 | 0.6363 | 0.2151 | |
| SRP064894 | APBB1IP | 54518 | RNAseq | 0.4290 | 0.1891 | |
| SRP133303 | APBB1IP | 54518 | RNAseq | -0.3334 | 0.1451 | |
| SRP159526 | APBB1IP | 54518 | RNAseq | -0.9011 | 0.2372 | |
| SRP193095 | APBB1IP | 54518 | RNAseq | 0.1517 | 0.5701 | |
| SRP219564 | APBB1IP | 54518 | RNAseq | 0.8866 | 0.0544 | |
| TCGA | APBB1IP | 54518 | RNAseq | -0.1198 | 0.4998 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by APBB1IP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of APBB1IP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | APBB1IP | 54518 | 4 | 7 | 19 | |
| GSE20123 | APBB1IP | 54518 | 5 | 6 | 19 | |
| GSE43470 | APBB1IP | 54518 | 3 | 4 | 36 | |
| GSE46452 | APBB1IP | 54518 | 1 | 14 | 44 | |
| GSE47630 | APBB1IP | 54518 | 5 | 15 | 20 | |
| GSE54993 | APBB1IP | 54518 | 9 | 0 | 61 | |
| GSE54994 | APBB1IP | 54518 | 3 | 9 | 41 | |
| GSE60625 | APBB1IP | 54518 | 0 | 0 | 11 | |
| GSE74703 | APBB1IP | 54518 | 2 | 2 | 32 | |
| GSE74704 | APBB1IP | 54518 | 0 | 5 | 15 | |
| TCGA | APBB1IP | 54518 | 18 | 24 | 54 |
Total number of gains: 50; Total number of losses: 86; Total Number of normals: 352.
Somatic mutations of APBB1IP:
Generating mutation plots.
Highly correlated genes for APBB1IP:
Showing top 20/595 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| APBB1IP | PREX1 | 0.854922 | 4 | 0 | 4 |
| APBB1IP | TNFSF8 | 0.818943 | 5 | 0 | 5 |
| APBB1IP | PARP15 | 0.789068 | 4 | 0 | 4 |
| APBB1IP | CXCL9 | 0.788564 | 3 | 0 | 3 |
| APBB1IP | CD53 | 0.787629 | 5 | 0 | 4 |
| APBB1IP | ZNF578 | 0.784383 | 3 | 0 | 3 |
| APBB1IP | ANKRD44 | 0.772488 | 6 | 0 | 6 |
| APBB1IP | AKNA | 0.771455 | 4 | 0 | 4 |
| APBB1IP | ARHGAP9 | 0.766687 | 7 | 0 | 6 |
| APBB1IP | TNFSF13B | 0.761677 | 6 | 0 | 6 |
| APBB1IP | RCSD1 | 0.751191 | 6 | 0 | 6 |
| APBB1IP | C1orf162 | 0.750255 | 7 | 0 | 6 |
| APBB1IP | CR1L | 0.749164 | 4 | 0 | 4 |
| APBB1IP | LCK | 0.74906 | 6 | 0 | 6 |
| APBB1IP | SNX20 | 0.741168 | 6 | 0 | 5 |
| APBB1IP | CLEC11A | 0.737494 | 3 | 0 | 3 |
| APBB1IP | RAPGEF1 | 0.73706 | 3 | 0 | 3 |
| APBB1IP | DGKQ | 0.735507 | 3 | 0 | 3 |
| APBB1IP | GAP43 | 0.733128 | 3 | 0 | 3 |
| APBB1IP | TNFSF4 | 0.731837 | 4 | 0 | 3 |
For details and further investigation, click here
