ZNF407

 

Full name: zinc finger protein 407 Alias Symbol: FLJ20307|FLJ13839|KIAA1703
Type: protein-coding gene Cytoband: 18q23
Entrez ID: 55628 HGNC ID: HGNC:19904 Ensembl Gene: ENSG00000215421 OMIM ID: 615894
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of ZNF407:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNF407 55628 227768_at -0.4005 0.1758
GSE20347 ZNF407 55628 220835_s_at 0.0261 0.6815
GSE23400 ZNF407 55628 220835_s_at -0.0164 0.3871
GSE26886 ZNF407 55628 227768_at -0.4981 0.0037
GSE29001 ZNF407 55628 220835_s_at 0.0089 0.9368
GSE38129 ZNF407 55628 220835_s_at -0.0183 0.7194
GSE45670 ZNF407 55628 227768_at -0.1272 0.3885
GSE53622 ZNF407 55628 51646 -0.0697 0.3450
GSE53624 ZNF407 55628 51646 0.0896 0.2414
GSE63941 ZNF407 55628 227768_at -1.5208 0.0002
GSE77861 ZNF407 55628 227768_at 0.1909 0.2415
GSE97050 ZNF407 55628 A_33_P3414402 -0.1311 0.5291
SRP007169 ZNF407 55628 RNAseq 1.2578 0.0053
SRP008496 ZNF407 55628 RNAseq 1.2156 0.0010
SRP064894 ZNF407 55628 RNAseq -0.2419 0.2027
SRP133303 ZNF407 55628 RNAseq -0.1628 0.1883
SRP159526 ZNF407 55628 RNAseq -0.2189 0.4435
SRP193095 ZNF407 55628 RNAseq -0.0934 0.4267
SRP219564 ZNF407 55628 RNAseq -0.3554 0.4451
TCGA ZNF407 55628 RNAseq -0.1375 0.0195

Upregulated datasets: 2; Downregulated datasets: 1.  


 

Survival by ZNF407 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZNF407:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF407 55628 0 11 19
GSE20123 ZNF407 55628 0 11 19
GSE43470 ZNF407 55628 0 8 35
GSE46452 ZNF407 55628 1 26 32
GSE47630 ZNF407 55628 5 22 13
GSE54993 ZNF407 55628 9 0 61
GSE54994 ZNF407 55628 1 18 34
GSE60625 ZNF407 55628 0 4 7
GSE74703 ZNF407 55628 0 7 29
GSE74704 ZNF407 55628 0 9 11
TCGA ZNF407 55628 6 49 41

Total number of gains: 22; Total number of losses: 165; Total Number of normals: 301.  


 

Somatic mutations of ZNF407:

 

Generating mutation plots.

 

Highly correlated genes for ZNF407:

 

Showing top 20/268 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF407ASPA0.842238303
ZNF407IL330.810349303
ZNF407ST6GALNAC60.79106303
ZNF407FRY0.781725303
ZNF407COL14A10.778064303
ZNF407USP9Y0.772058303
ZNF407DCAF100.771463303
ZNF407GNG120.767704303
ZNF407ADAMTS80.763037303
ZNF407ANGPTL10.762415303
ZNF407BDNF0.760833303
ZNF407ALDH6A10.760729303
ZNF407TGFBR30.758957303
ZNF407ACO10.754615303
ZNF407PTP4A20.749211303
ZNF407NKAPL0.748047403
ZNF407SH3D190.743656303
ZNF407GBE10.739956303
ZNF407PTPN210.735872303
ZNF407ZNF4410.733477403

For details and further investigation, click here