| Full name: sorting nexin 3 | Alias Symbol: Grd19 | ||
| Type: protein-coding gene | Cytoband: 6q21 | ||
| Entrez ID: 8724 | HGNC ID: HGNC:11174 | Ensembl Gene: ENSG00000112335 | OMIM ID: 605930 |
| Drug and gene relationship at DGIdb | |||
Expression of SNX3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNX3 | 8724 | 210648_x_at | -0.6724 | 0.0209 | |
| GSE20347 | SNX3 | 8724 | 210648_x_at | -0.7622 | 0.0000 | |
| GSE23400 | SNX3 | 8724 | 210648_x_at | -0.3855 | 0.0000 | |
| GSE26886 | SNX3 | 8724 | 210648_x_at | -0.7025 | 0.0000 | |
| GSE29001 | SNX3 | 8724 | 210648_x_at | -0.5792 | 0.0130 | |
| GSE38129 | SNX3 | 8724 | 210648_x_at | -0.6676 | 0.0000 | |
| GSE45670 | SNX3 | 8724 | 210648_x_at | -0.4501 | 0.0000 | |
| GSE53622 | SNX3 | 8724 | 163182 | -0.5776 | 0.0000 | |
| GSE53624 | SNX3 | 8724 | 89947 | -0.6815 | 0.0000 | |
| GSE63941 | SNX3 | 8724 | 210648_x_at | -0.4143 | 0.1883 | |
| GSE77861 | SNX3 | 8724 | 210648_x_at | -0.7000 | 0.0036 | |
| GSE97050 | SNX3 | 8724 | A_24_P277807 | -0.3307 | 0.2209 | |
| SRP007169 | SNX3 | 8724 | RNAseq | -1.6801 | 0.0000 | |
| SRP008496 | SNX3 | 8724 | RNAseq | -1.6017 | 0.0000 | |
| SRP064894 | SNX3 | 8724 | RNAseq | -0.4820 | 0.0006 | |
| SRP133303 | SNX3 | 8724 | RNAseq | -0.3164 | 0.0239 | |
| SRP159526 | SNX3 | 8724 | RNAseq | -0.7454 | 0.0084 | |
| SRP193095 | SNX3 | 8724 | RNAseq | -0.9204 | 0.0000 | |
| SRP219564 | SNX3 | 8724 | RNAseq | -0.6201 | 0.1112 | |
| TCGA | SNX3 | 8724 | RNAseq | 0.0003 | 0.9953 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by SNX3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNX3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNX3 | 8724 | 2 | 3 | 25 | |
| GSE20123 | SNX3 | 8724 | 2 | 2 | 26 | |
| GSE43470 | SNX3 | 8724 | 3 | 1 | 39 | |
| GSE46452 | SNX3 | 8724 | 2 | 11 | 46 | |
| GSE47630 | SNX3 | 8724 | 9 | 4 | 27 | |
| GSE54993 | SNX3 | 8724 | 3 | 2 | 65 | |
| GSE54994 | SNX3 | 8724 | 8 | 8 | 37 | |
| GSE60625 | SNX3 | 8724 | 0 | 2 | 9 | |
| GSE74703 | SNX3 | 8724 | 2 | 1 | 33 | |
| GSE74704 | SNX3 | 8724 | 0 | 0 | 20 | |
| TCGA | SNX3 | 8724 | 6 | 23 | 67 |
Total number of gains: 37; Total number of losses: 57; Total Number of normals: 394.
Somatic mutations of SNX3:
Generating mutation plots.
Highly correlated genes for SNX3:
Showing top 20/1402 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNX3 | SFTA2 | 0.767273 | 4 | 0 | 4 |
| SNX3 | C4orf3 | 0.766952 | 6 | 0 | 6 |
| SNX3 | TMPRSS11B | 0.751736 | 6 | 0 | 6 |
| SNX3 | KRT78 | 0.751065 | 6 | 0 | 6 |
| SNX3 | FCHO2 | 0.747611 | 8 | 0 | 7 |
| SNX3 | FAM214A | 0.736427 | 6 | 0 | 6 |
| SNX3 | SNORA68 | 0.734538 | 4 | 0 | 4 |
| SNX3 | CGNL1 | 0.734367 | 7 | 0 | 7 |
| SNX3 | BRK1 | 0.732681 | 7 | 0 | 7 |
| SNX3 | VSIG10L | 0.725117 | 6 | 0 | 6 |
| SNX3 | RAP1A | 0.724987 | 11 | 0 | 11 |
| SNX3 | YAP1 | 0.724258 | 4 | 0 | 4 |
| SNX3 | CRISP3 | 0.722678 | 10 | 0 | 10 |
| SNX3 | EPB41L3 | 0.72151 | 11 | 0 | 11 |
| SNX3 | RHOA | 0.719448 | 12 | 0 | 12 |
| SNX3 | HCG22 | 0.718683 | 6 | 0 | 6 |
| SNX3 | ATP6V1C2 | 0.714938 | 4 | 0 | 4 |
| SNX3 | CYSRT1 | 0.714781 | 6 | 0 | 6 |
| SNX3 | FAM3D | 0.714284 | 6 | 0 | 6 |
| SNX3 | SPNS2 | 0.713825 | 5 | 0 | 5 |
For details and further investigation, click here
