| Full name: general transcription factor IIIC subunit 5 | Alias Symbol: TFiiiC2-63|TFIIIC63|TFIIICepsilon | ||
| Type: protein-coding gene | Cytoband: 9q34.13 | ||
| Entrez ID: 9328 | HGNC ID: HGNC:4668 | Ensembl Gene: ENSG00000148308 | OMIM ID: 604890 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of GTF3C5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GTF3C5 | 9328 | 233173_x_at | 0.3955 | 0.3103 | |
| GSE20347 | GTF3C5 | 9328 | 217876_at | 0.0022 | 0.9884 | |
| GSE23400 | GTF3C5 | 9328 | 217876_at | -0.0264 | 0.4757 | |
| GSE26886 | GTF3C5 | 9328 | 233173_x_at | 0.6465 | 0.0001 | |
| GSE29001 | GTF3C5 | 9328 | 217876_at | -0.0140 | 0.9497 | |
| GSE38129 | GTF3C5 | 9328 | 217876_at | 0.0521 | 0.5637 | |
| GSE45670 | GTF3C5 | 9328 | 233173_x_at | 0.3556 | 0.0008 | |
| GSE53622 | GTF3C5 | 9328 | 78190 | 0.0710 | 0.1707 | |
| GSE53624 | GTF3C5 | 9328 | 78190 | -0.0865 | 0.1970 | |
| GSE63941 | GTF3C5 | 9328 | 233173_x_at | 1.2393 | 0.0004 | |
| GSE77861 | GTF3C5 | 9328 | 233173_x_at | 0.2810 | 0.1025 | |
| GSE97050 | GTF3C5 | 9328 | A_23_P112406 | -0.1727 | 0.4447 | |
| SRP007169 | GTF3C5 | 9328 | RNAseq | 0.1878 | 0.5834 | |
| SRP008496 | GTF3C5 | 9328 | RNAseq | 0.1574 | 0.4560 | |
| SRP064894 | GTF3C5 | 9328 | RNAseq | 0.6959 | 0.0046 | |
| SRP133303 | GTF3C5 | 9328 | RNAseq | 0.2472 | 0.1208 | |
| SRP159526 | GTF3C5 | 9328 | RNAseq | 0.5804 | 0.0000 | |
| SRP193095 | GTF3C5 | 9328 | RNAseq | 0.3119 | 0.0183 | |
| SRP219564 | GTF3C5 | 9328 | RNAseq | 0.1344 | 0.6971 | |
| TCGA | GTF3C5 | 9328 | RNAseq | 0.2167 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GTF3C5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GTF3C5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GTF3C5 | 9328 | 5 | 7 | 18 | |
| GSE20123 | GTF3C5 | 9328 | 5 | 7 | 18 | |
| GSE43470 | GTF3C5 | 9328 | 4 | 7 | 32 | |
| GSE46452 | GTF3C5 | 9328 | 6 | 13 | 40 | |
| GSE47630 | GTF3C5 | 9328 | 4 | 15 | 21 | |
| GSE54993 | GTF3C5 | 9328 | 3 | 3 | 64 | |
| GSE54994 | GTF3C5 | 9328 | 12 | 9 | 32 | |
| GSE60625 | GTF3C5 | 9328 | 0 | 0 | 11 | |
| GSE74703 | GTF3C5 | 9328 | 4 | 5 | 27 | |
| GSE74704 | GTF3C5 | 9328 | 3 | 5 | 12 | |
| TCGA | GTF3C5 | 9328 | 28 | 26 | 42 |
Total number of gains: 74; Total number of losses: 97; Total Number of normals: 317.
Somatic mutations of GTF3C5:
Generating mutation plots.
Highly correlated genes for GTF3C5:
Showing top 20/310 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GTF3C5 | C19orf25 | 0.752591 | 3 | 0 | 3 |
| GTF3C5 | TRIM11 | 0.712053 | 5 | 0 | 5 |
| GTF3C5 | SYT1 | 0.710144 | 3 | 0 | 3 |
| GTF3C5 | TSR3 | 0.703691 | 3 | 0 | 3 |
| GTF3C5 | METTL18 | 0.701164 | 3 | 0 | 3 |
| GTF3C5 | DHX9 | 0.696747 | 6 | 0 | 5 |
| GTF3C5 | LINC00467 | 0.68907 | 3 | 0 | 3 |
| GTF3C5 | SNORA71A | 0.686363 | 3 | 0 | 3 |
| GTF3C5 | COLGALT1 | 0.682758 | 4 | 0 | 4 |
| GTF3C5 | C19orf53 | 0.675693 | 4 | 0 | 3 |
| GTF3C5 | TOP3B | 0.668899 | 3 | 0 | 3 |
| GTF3C5 | ABCC10 | 0.665387 | 4 | 0 | 4 |
| GTF3C5 | NCOA5 | 0.65843 | 3 | 0 | 3 |
| GTF3C5 | ISL2 | 0.657312 | 3 | 0 | 3 |
| GTF3C5 | ZFP41 | 0.653004 | 3 | 0 | 3 |
| GTF3C5 | NTMT1 | 0.652632 | 3 | 0 | 3 |
| GTF3C5 | ZNF511 | 0.652088 | 4 | 0 | 4 |
| GTF3C5 | JRK | 0.651824 | 4 | 0 | 3 |
| GTF3C5 | LRRC8D | 0.651426 | 3 | 0 | 3 |
| GTF3C5 | PCP2 | 0.650258 | 3 | 0 | 3 |
For details and further investigation, click here
