ABCC10

 

Full name: ATP binding cassette subfamily C member 10 Alias Symbol: EST182763|MRP7|SIMRP7
Type: protein-coding gene Cytoband: 6p21.1
Entrez ID: 89845 HGNC ID: HGNC:52 Ensembl Gene: ENSG00000124574 OMIM ID: 612509
Drug and gene relationship at DGIdb

 

Expression of ABCC10:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ABCC10 89845 213485_s_at 0.5264 0.1004
GSE20347 ABCC10 89845 213485_s_at 0.1612 0.4509
GSE23400 ABCC10 89845 213485_s_at 0.3515 0.0000
GSE26886 ABCC10 89845 213485_s_at 1.7707 0.0000
GSE29001 ABCC10 89845 213485_s_at -0.1402 0.6817
GSE38129 ABCC10 89845 213485_s_at 0.3830 0.0291
GSE45670 ABCC10 89845 213485_s_at 0.2909 0.0657
GSE53622 ABCC10 89845 15944 0.3089 0.0000
GSE53624 ABCC10 89845 15944 0.2896 0.0000
GSE63941 ABCC10 89845 213485_s_at 0.1065 0.8450
GSE77861 ABCC10 89845 215873_x_at 0.0481 0.8473
GSE97050 ABCC10 89845 A_33_P3372566 0.2951 0.3315
SRP007169 ABCC10 89845 RNAseq 0.1715 0.7079
SRP008496 ABCC10 89845 RNAseq 0.0811 0.7345
SRP064894 ABCC10 89845 RNAseq 0.5525 0.0006
SRP133303 ABCC10 89845 RNAseq 0.1632 0.2761
SRP159526 ABCC10 89845 RNAseq 0.1730 0.3847
SRP193095 ABCC10 89845 RNAseq 0.2470 0.0625
SRP219564 ABCC10 89845 RNAseq 0.5573 0.0447
TCGA ABCC10 89845 RNAseq 0.1026 0.0673

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by ABCC10 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ABCC10:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ABCC10 89845 7 0 23
GSE20123 ABCC10 89845 7 0 23
GSE43470 ABCC10 89845 6 0 37
GSE46452 ABCC10 89845 2 9 48
GSE47630 ABCC10 89845 8 4 28
GSE54993 ABCC10 89845 3 2 65
GSE54994 ABCC10 89845 11 4 38
GSE60625 ABCC10 89845 0 1 10
GSE74703 ABCC10 89845 6 0 30
GSE74704 ABCC10 89845 3 0 17
TCGA ABCC10 89845 20 13 63

Total number of gains: 73; Total number of losses: 33; Total Number of normals: 382.  

 

Somatic mutations of ABCC10:

 

Generating mutation plots.

 

Highly correlated genes for ABCC10:

 

Showing top 20/292 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ABCC10PRPF80.731572403
ABCC10PLA2G150.725221403
ABCC10UGGT10.717541303
ABCC10CD2760.716852303
ABCC10NOC4L0.691897403
ABCC10RHPN20.690213303
ABCC10TSEN540.688518303
ABCC10ATG2A0.677925403
ABCC10COL10A10.675506403
ABCC10GTF2IRD20.673362403
ABCC10GTF3C50.665387404
ABCC10ALG10.658579303
ABCC10CTNS0.648905403
ABCC10WRAP530.647736403
ABCC10CA90.634717403
ABCC10KRTCAP20.630435303
ABCC10METTL10.629337603
ABCC10RAB150.627952403
ABCC10MED160.624683404
ABCC10RUVBL20.62084603

For details and further investigation, click here