| Full name: methyltransferase like 18 | Alias Symbol: MGC9084|AsTP2|HPM1 | ||
| Type: protein-coding gene | Cytoband: 1q24.2 | ||
| Entrez ID: 92342 | HGNC ID: HGNC:28793 | Ensembl Gene: ENSG00000171806 | OMIM ID: 615255 |
Expression of METTL18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | METTL18 | 92342 | 213528_at | -0.0612 | 0.9399 | |
| GSE20347 | METTL18 | 92342 | 213528_at | 0.1052 | 0.5744 | |
| GSE23400 | METTL18 | 92342 | 213528_at | 0.1098 | 0.0034 | |
| GSE26886 | METTL18 | 92342 | 213528_at | -0.3484 | 0.3990 | |
| GSE29001 | METTL18 | 92342 | 213528_at | 0.1667 | 0.6502 | |
| GSE38129 | METTL18 | 92342 | 213528_at | 0.1726 | 0.1308 | |
| GSE45670 | METTL18 | 92342 | 213528_at | 0.0581 | 0.7211 | |
| GSE53622 | METTL18 | 92342 | 111549 | 0.2700 | 0.0004 | |
| GSE53624 | METTL18 | 92342 | 111549 | 0.0577 | 0.5988 | |
| GSE63941 | METTL18 | 92342 | 213528_at | 1.0184 | 0.0052 | |
| GSE77861 | METTL18 | 92342 | 213528_at | 0.3717 | 0.2012 | |
| GSE97050 | METTL18 | 92342 | A_23_P85726 | -0.0461 | 0.9172 | |
| SRP007169 | METTL18 | 92342 | RNAseq | -0.1444 | 0.7849 | |
| SRP008496 | METTL18 | 92342 | RNAseq | 0.3228 | 0.4379 | |
| SRP064894 | METTL18 | 92342 | RNAseq | -0.1832 | 0.3814 | |
| SRP133303 | METTL18 | 92342 | RNAseq | -0.1475 | 0.5095 | |
| SRP159526 | METTL18 | 92342 | RNAseq | 0.2478 | 0.3699 | |
| SRP193095 | METTL18 | 92342 | RNAseq | -0.2592 | 0.1234 | |
| SRP219564 | METTL18 | 92342 | RNAseq | 0.2180 | 0.4824 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by METTL18 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of METTL18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | METTL18 | 92342 | 12 | 1 | 17 | |
| GSE20123 | METTL18 | 92342 | 12 | 1 | 17 | |
| GSE43470 | METTL18 | 92342 | 7 | 2 | 34 | |
| GSE46452 | METTL18 | 92342 | 3 | 1 | 55 | |
| GSE47630 | METTL18 | 92342 | 14 | 0 | 26 | |
| GSE54993 | METTL18 | 92342 | 0 | 6 | 64 | |
| GSE54994 | METTL18 | 92342 | 16 | 0 | 37 | |
| GSE60625 | METTL18 | 92342 | 0 | 0 | 11 | |
| GSE74703 | METTL18 | 92342 | 7 | 2 | 27 | |
| GSE74704 | METTL18 | 92342 | 6 | 0 | 14 | |
| TCGA | METTL18 | 92342 | 43 | 3 | 50 |
Total number of gains: 120; Total number of losses: 16; Total Number of normals: 352.
Somatic mutations of METTL18:
Generating mutation plots.
Highly correlated genes for METTL18:
Showing top 20/39 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| METTL18 | HOMER1 | 0.721369 | 3 | 0 | 3 |
| METTL18 | TFAP2C | 0.703516 | 3 | 0 | 3 |
| METTL18 | ARFGEF1 | 0.702767 | 3 | 0 | 3 |
| METTL18 | GTF3C5 | 0.701164 | 3 | 0 | 3 |
| METTL18 | HDHD3 | 0.640612 | 3 | 0 | 3 |
| METTL18 | SAMD13 | 0.640604 | 3 | 0 | 3 |
| METTL18 | C5orf34 | 0.63176 | 4 | 0 | 3 |
| METTL18 | ZADH2 | 0.61082 | 3 | 0 | 3 |
| METTL18 | FANCF | 0.597557 | 6 | 0 | 5 |
| METTL18 | ZNF19 | 0.589768 | 5 | 0 | 3 |
| METTL18 | CXADR | 0.580275 | 4 | 0 | 3 |
| METTL18 | NRF1 | 0.574493 | 3 | 0 | 3 |
| METTL18 | METTL4 | 0.573317 | 5 | 0 | 3 |
| METTL18 | ZSCAN25 | 0.568265 | 4 | 0 | 4 |
| METTL18 | YIPF6 | 0.560154 | 4 | 0 | 3 |
| METTL18 | RTCB | 0.55938 | 4 | 0 | 4 |
| METTL18 | ABT1 | 0.551403 | 6 | 0 | 5 |
| METTL18 | BCL11B | 0.549506 | 5 | 0 | 3 |
| METTL18 | COQ5 | 0.548783 | 6 | 0 | 4 |
| METTL18 | HS2ST1 | 0.548169 | 6 | 0 | 3 |
For details and further investigation, click here
