| Full name: TSR3 ribosome maturation factor | Alias Symbol: MGC24381 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 115939 | HGNC ID: HGNC:14175 | Ensembl Gene: ENSG00000007520 | OMIM ID: 617058 |
Screen Evidence:
| |||
Expression of TSR3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TSR3 | 115939 | 213105_s_at | 0.4981 | 0.1641 | |
| GSE20347 | TSR3 | 115939 | 213105_s_at | 0.2383 | 0.1076 | |
| GSE23400 | TSR3 | 115939 | 213105_s_at | 0.1871 | 0.0021 | |
| GSE26886 | TSR3 | 115939 | 213105_s_at | 0.7756 | 0.0006 | |
| GSE29001 | TSR3 | 115939 | 213105_s_at | 0.3803 | 0.3465 | |
| GSE38129 | TSR3 | 115939 | 213105_s_at | 0.2512 | 0.0265 | |
| GSE45670 | TSR3 | 115939 | 213105_s_at | 0.3766 | 0.0005 | |
| GSE53622 | TSR3 | 115939 | 14679 | 0.0522 | 0.3325 | |
| GSE53624 | TSR3 | 115939 | 14679 | 0.1963 | 0.0148 | |
| GSE63941 | TSR3 | 115939 | 213104_at | 0.1855 | 0.5405 | |
| GSE77861 | TSR3 | 115939 | 213104_at | 0.0007 | 0.9980 | |
| SRP007169 | TSR3 | 115939 | RNAseq | -0.3927 | 0.2406 | |
| SRP008496 | TSR3 | 115939 | RNAseq | -0.0650 | 0.7610 | |
| SRP064894 | TSR3 | 115939 | RNAseq | 0.5084 | 0.1689 | |
| SRP133303 | TSR3 | 115939 | RNAseq | 0.3261 | 0.0462 | |
| SRP159526 | TSR3 | 115939 | RNAseq | 0.0146 | 0.9575 | |
| SRP193095 | TSR3 | 115939 | RNAseq | 0.0045 | 0.9736 | |
| SRP219564 | TSR3 | 115939 | RNAseq | 0.1340 | 0.7498 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TSR3 expression:
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| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of TSR3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TSR3 | 115939 | 5 | 5 | 20 | |
| GSE20123 | TSR3 | 115939 | 5 | 4 | 21 | |
| GSE43470 | TSR3 | 115939 | 4 | 7 | 32 | |
| GSE46452 | TSR3 | 115939 | 38 | 1 | 20 | |
| GSE47630 | TSR3 | 115939 | 13 | 6 | 21 | |
| GSE54993 | TSR3 | 115939 | 3 | 5 | 62 | |
| GSE54994 | TSR3 | 115939 | 5 | 9 | 39 | |
| GSE60625 | TSR3 | 115939 | 4 | 0 | 7 | |
| GSE74703 | TSR3 | 115939 | 4 | 5 | 27 | |
| GSE74704 | TSR3 | 115939 | 3 | 2 | 15 | |
| TCGA | TSR3 | 115939 | 19 | 14 | 63 |
Total number of gains: 103; Total number of losses: 58; Total Number of normals: 327.
Somatic mutations of TSR3:
Generating mutation plots.
Highly correlated genes for TSR3:
Showing top 20/587 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TSR3 | CMSS1 | 0.750271 | 3 | 0 | 3 |
| TSR3 | SURF6 | 0.717416 | 3 | 0 | 3 |
| TSR3 | GTF3C5 | 0.703691 | 3 | 0 | 3 |
| TSR3 | MRPS34 | 0.700294 | 11 | 0 | 11 |
| TSR3 | YWHAG | 0.697868 | 3 | 0 | 3 |
| TSR3 | PSMG3 | 0.697723 | 4 | 0 | 4 |
| TSR3 | GNPTG | 0.695929 | 4 | 0 | 4 |
| TSR3 | NIFK | 0.694133 | 3 | 0 | 3 |
| TSR3 | WRAP73 | 0.6868 | 3 | 0 | 3 |
| TSR3 | EPPK1 | 0.682831 | 3 | 0 | 3 |
| TSR3 | MRPL28 | 0.682078 | 11 | 0 | 10 |
| TSR3 | ZNF574 | 0.679105 | 3 | 0 | 3 |
| TSR3 | COCH | 0.674864 | 3 | 0 | 3 |
| TSR3 | SRRT | 0.672126 | 3 | 0 | 3 |
| TSR3 | FBLIM1 | 0.670332 | 3 | 0 | 3 |
| TSR3 | HOXD13 | 0.668713 | 3 | 0 | 3 |
| TSR3 | RPL24 | 0.666608 | 3 | 0 | 3 |
| TSR3 | ZBTB48 | 0.664338 | 3 | 0 | 3 |
| TSR3 | GAS6-AS1 | 0.663611 | 3 | 0 | 3 |
| TSR3 | FOXH1 | 0.663127 | 3 | 0 | 3 |
For details and further investigation, click here
