| Full name: NOP58 ribonucleoprotein | Alias Symbol: NOP5|HSPC120 | ||
| Type: protein-coding gene | Cytoband: 2q33.1 | ||
| Entrez ID: 51602 | HGNC ID: HGNC:29926 | Ensembl Gene: ENSG00000055044 | OMIM ID: 616742 |
| Drug and gene relationship at DGIdb | |||
Expression of NOP58:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOP58 | 51602 | 223096_at | 0.5419 | 0.4140 | |
| GSE26886 | NOP58 | 51602 | 223096_at | 1.3839 | 0.0000 | |
| GSE45670 | NOP58 | 51602 | 223096_at | 0.7006 | 0.0004 | |
| GSE53622 | NOP58 | 51602 | 108494 | 0.6671 | 0.0000 | |
| GSE53624 | NOP58 | 51602 | 108494 | 0.8964 | 0.0000 | |
| GSE63941 | NOP58 | 51602 | 223096_at | 0.6808 | 0.0315 | |
| GSE77861 | NOP58 | 51602 | 223096_at | 0.8299 | 0.0013 | |
| GSE97050 | NOP58 | 51602 | A_23_P154447 | 0.4883 | 0.2204 | |
| SRP007169 | NOP58 | 51602 | RNAseq | 0.8224 | 0.0234 | |
| SRP008496 | NOP58 | 51602 | RNAseq | 0.9892 | 0.0010 | |
| SRP064894 | NOP58 | 51602 | RNAseq | 0.3386 | 0.0291 | |
| SRP133303 | NOP58 | 51602 | RNAseq | 0.5954 | 0.0009 | |
| SRP159526 | NOP58 | 51602 | RNAseq | 0.3511 | 0.0992 | |
| SRP193095 | NOP58 | 51602 | RNAseq | 0.3637 | 0.0010 | |
| SRP219564 | NOP58 | 51602 | RNAseq | 0.3546 | 0.1992 | |
| TCGA | NOP58 | 51602 | RNAseq | 0.2412 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NOP58 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NOP58:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOP58 | 51602 | 7 | 4 | 19 | |
| GSE20123 | NOP58 | 51602 | 7 | 4 | 19 | |
| GSE43470 | NOP58 | 51602 | 1 | 3 | 39 | |
| GSE46452 | NOP58 | 51602 | 1 | 4 | 54 | |
| GSE47630 | NOP58 | 51602 | 4 | 5 | 31 | |
| GSE54993 | NOP58 | 51602 | 0 | 3 | 67 | |
| GSE54994 | NOP58 | 51602 | 10 | 8 | 35 | |
| GSE60625 | NOP58 | 51602 | 0 | 3 | 8 | |
| GSE74703 | NOP58 | 51602 | 1 | 2 | 33 | |
| GSE74704 | NOP58 | 51602 | 3 | 2 | 15 | |
| TCGA | NOP58 | 51602 | 21 | 11 | 64 |
Total number of gains: 55; Total number of losses: 49; Total Number of normals: 384.
Somatic mutations of NOP58:
Generating mutation plots.
Highly correlated genes for NOP58:
Showing top 20/1749 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOP58 | XPR1 | 0.776084 | 6 | 0 | 6 |
| NOP58 | EXOC6 | 0.772633 | 3 | 0 | 3 |
| NOP58 | MTERF3 | 0.768649 | 4 | 0 | 4 |
| NOP58 | CBFA2T2 | 0.758051 | 3 | 0 | 3 |
| NOP58 | ALKBH6 | 0.757994 | 5 | 0 | 5 |
| NOP58 | PYCR2 | 0.754782 | 3 | 0 | 3 |
| NOP58 | PFDN2 | 0.753562 | 8 | 0 | 7 |
| NOP58 | SLC19A1 | 0.751942 | 3 | 0 | 3 |
| NOP58 | SSB | 0.751239 | 9 | 0 | 8 |
| NOP58 | PRPF40A | 0.750854 | 7 | 0 | 7 |
| NOP58 | CHAF1B | 0.750398 | 3 | 0 | 3 |
| NOP58 | E2F3 | 0.747465 | 7 | 0 | 7 |
| NOP58 | ITPR3 | 0.746984 | 6 | 0 | 6 |
| NOP58 | RPL39L | 0.74682 | 6 | 0 | 6 |
| NOP58 | DNAJC2 | 0.746817 | 9 | 0 | 9 |
| NOP58 | GSR | 0.745478 | 3 | 0 | 3 |
| NOP58 | TTL | 0.743622 | 6 | 0 | 6 |
| NOP58 | PLCG1 | 0.743041 | 3 | 0 | 3 |
| NOP58 | NAP1L1 | 0.74282 | 3 | 0 | 3 |
| NOP58 | RAD23A | 0.741729 | 5 | 0 | 5 |
For details and further investigation, click here
