| Full name: guanylate cyclase activator 1A | Alias Symbol: GCAP|GCAP1|COD3|dJ139D8.6|CORD14 | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 2978 | HGNC ID: HGNC:4678 | Ensembl Gene: ENSG00000048545 | OMIM ID: 600364 |
| Drug and gene relationship at DGIdb | |||
Expression of GUCA1A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GUCA1A | 2978 | 231700_at | -0.1223 | 0.7106 | |
| GSE20347 | GUCA1A | 2978 | 206062_at | 0.1718 | 0.0363 | |
| GSE23400 | GUCA1A | 2978 | 206062_at | 0.0478 | 0.2510 | |
| GSE26886 | GUCA1A | 2978 | 231700_at | 0.0945 | 0.5147 | |
| GSE29001 | GUCA1A | 2978 | 206062_at | -0.0069 | 0.9722 | |
| GSE38129 | GUCA1A | 2978 | 206062_at | 0.1025 | 0.2497 | |
| GSE45670 | GUCA1A | 2978 | 231700_at | 0.0763 | 0.3955 | |
| GSE53622 | GUCA1A | 2978 | 55973 | 1.8687 | 0.0000 | |
| GSE53624 | GUCA1A | 2978 | 62885 | 1.5960 | 0.0000 | |
| GSE63941 | GUCA1A | 2978 | 231700_at | 0.2390 | 0.1978 | |
| GSE77861 | GUCA1A | 2978 | 231700_at | -0.0831 | 0.4969 | |
| TCGA | GUCA1A | 2978 | RNAseq | 2.8762 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by GUCA1A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GUCA1A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GUCA1A | 2978 | 7 | 0 | 23 | |
| GSE20123 | GUCA1A | 2978 | 7 | 0 | 23 | |
| GSE43470 | GUCA1A | 2978 | 6 | 0 | 37 | |
| GSE46452 | GUCA1A | 2978 | 2 | 9 | 48 | |
| GSE47630 | GUCA1A | 2978 | 8 | 4 | 28 | |
| GSE54993 | GUCA1A | 2978 | 3 | 2 | 65 | |
| GSE54994 | GUCA1A | 2978 | 11 | 4 | 38 | |
| GSE60625 | GUCA1A | 2978 | 0 | 1 | 10 | |
| GSE74703 | GUCA1A | 2978 | 6 | 0 | 30 | |
| GSE74704 | GUCA1A | 2978 | 3 | 0 | 17 | |
| TCGA | GUCA1A | 2978 | 20 | 13 | 63 |
Total number of gains: 73; Total number of losses: 33; Total Number of normals: 382.
Somatic mutations of GUCA1A:
Generating mutation plots.
Highly correlated genes for GUCA1A:
Showing top 20/303 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GUCA1A | SSC5D | 0.737444 | 3 | 0 | 3 |
| GUCA1A | GATA6 | 0.70818 | 3 | 0 | 3 |
| GUCA1A | NR4A1 | 0.690214 | 4 | 0 | 4 |
| GUCA1A | ZMAT4 | 0.677667 | 4 | 0 | 4 |
| GUCA1A | AVPR2 | 0.668999 | 4 | 0 | 4 |
| GUCA1A | TAB1 | 0.662891 | 3 | 0 | 3 |
| GUCA1A | TTC9B | 0.65133 | 4 | 0 | 3 |
| GUCA1A | MAFK | 0.642384 | 3 | 0 | 3 |
| GUCA1A | SIX3-AS1 | 0.641063 | 3 | 0 | 3 |
| GUCA1A | SLC11A1 | 0.636435 | 5 | 0 | 5 |
| GUCA1A | P2RY4 | 0.633585 | 6 | 0 | 5 |
| GUCA1A | RHPN1-AS1 | 0.633452 | 3 | 0 | 3 |
| GUCA1A | ARC | 0.632025 | 4 | 0 | 3 |
| GUCA1A | THEG | 0.631657 | 4 | 0 | 4 |
| GUCA1A | FCGR2C | 0.626096 | 3 | 0 | 3 |
| GUCA1A | SLC26A10 | 0.624659 | 5 | 0 | 3 |
| GUCA1A | HAS1 | 0.623752 | 5 | 0 | 4 |
| GUCA1A | CLRN3 | 0.622968 | 3 | 0 | 3 |
| GUCA1A | KIR2DL5A | 0.621694 | 5 | 0 | 4 |
| GUCA1A | TRIM10 | 0.620619 | 7 | 0 | 6 |
For details and further investigation, click here
