| Full name: solute carrier family 11 member 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 6556 | HGNC ID: HGNC:10907 | Ensembl Gene: ENSG00000018280 | OMIM ID: 600266 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC11A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC11A1 | 6556 | 230382_at | -0.0419 | 0.9140 | |
| GSE20347 | SLC11A1 | 6556 | 217473_x_at | -0.0306 | 0.7714 | |
| GSE23400 | SLC11A1 | 6556 | 210422_x_at | -0.0957 | 0.0052 | |
| GSE26886 | SLC11A1 | 6556 | 230382_at | 0.2824 | 0.0138 | |
| GSE29001 | SLC11A1 | 6556 | 210423_s_at | 0.3945 | 0.0897 | |
| GSE38129 | SLC11A1 | 6556 | 210422_x_at | -0.1750 | 0.0439 | |
| GSE45670 | SLC11A1 | 6556 | 210422_x_at | 0.0299 | 0.7706 | |
| GSE53622 | SLC11A1 | 6556 | 31664 | 0.1387 | 0.1203 | |
| GSE53624 | SLC11A1 | 6556 | 31664 | -0.0017 | 0.9870 | |
| GSE63941 | SLC11A1 | 6556 | 217473_x_at | 0.5007 | 0.0130 | |
| GSE77861 | SLC11A1 | 6556 | 217473_x_at | -0.0866 | 0.3671 | |
| GSE97050 | SLC11A1 | 6556 | A_33_P3702055 | 0.1083 | 0.6011 | |
| SRP007169 | SLC11A1 | 6556 | RNAseq | 3.1412 | 0.0000 | |
| SRP008496 | SLC11A1 | 6556 | RNAseq | 2.8309 | 0.0000 | |
| SRP064894 | SLC11A1 | 6556 | RNAseq | 2.2805 | 0.0000 | |
| SRP133303 | SLC11A1 | 6556 | RNAseq | 2.6762 | 0.0000 | |
| SRP159526 | SLC11A1 | 6556 | RNAseq | 1.8952 | 0.0001 | |
| SRP193095 | SLC11A1 | 6556 | RNAseq | 2.7855 | 0.0000 | |
| SRP219564 | SLC11A1 | 6556 | RNAseq | 2.0135 | 0.0091 | |
| TCGA | SLC11A1 | 6556 | RNAseq | 0.4169 | 0.0045 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by SLC11A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC11A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC11A1 | 6556 | 1 | 14 | 15 | |
| GSE20123 | SLC11A1 | 6556 | 1 | 13 | 16 | |
| GSE43470 | SLC11A1 | 6556 | 1 | 7 | 35 | |
| GSE46452 | SLC11A1 | 6556 | 0 | 5 | 54 | |
| GSE47630 | SLC11A1 | 6556 | 4 | 5 | 31 | |
| GSE54993 | SLC11A1 | 6556 | 1 | 2 | 67 | |
| GSE54994 | SLC11A1 | 6556 | 8 | 10 | 35 | |
| GSE60625 | SLC11A1 | 6556 | 0 | 3 | 8 | |
| GSE74703 | SLC11A1 | 6556 | 1 | 5 | 30 | |
| GSE74704 | SLC11A1 | 6556 | 1 | 7 | 12 | |
| TCGA | SLC11A1 | 6556 | 11 | 29 | 56 |
Total number of gains: 29; Total number of losses: 100; Total Number of normals: 359.
Somatic mutations of SLC11A1:
Generating mutation plots.
Highly correlated genes for SLC11A1:
Showing top 20/479 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC11A1 | PI16 | 0.766679 | 3 | 0 | 3 |
| SLC11A1 | SAMD1 | 0.76047 | 3 | 0 | 3 |
| SLC11A1 | SFTPA2 | 0.756963 | 3 | 0 | 3 |
| SLC11A1 | RAB4B | 0.746677 | 3 | 0 | 3 |
| SLC11A1 | NR4A1 | 0.733995 | 3 | 0 | 3 |
| SLC11A1 | ZNF358 | 0.733352 | 3 | 0 | 3 |
| SLC11A1 | HES4 | 0.729096 | 4 | 0 | 4 |
| SLC11A1 | WFIKKN1 | 0.72902 | 3 | 0 | 3 |
| SLC11A1 | NFAM1 | 0.727858 | 3 | 0 | 3 |
| SLC11A1 | HELB | 0.725066 | 3 | 0 | 3 |
| SLC11A1 | ITGB3 | 0.720201 | 4 | 0 | 4 |
| SLC11A1 | C10orf82 | 0.715538 | 3 | 0 | 3 |
| SLC11A1 | CYP26C1 | 0.715514 | 3 | 0 | 3 |
| SLC11A1 | SORBS3 | 0.713878 | 3 | 0 | 3 |
| SLC11A1 | OR2T12 | 0.71271 | 3 | 0 | 3 |
| SLC11A1 | ELFN1 | 0.710575 | 4 | 0 | 4 |
| SLC11A1 | FGFRL1 | 0.710365 | 3 | 0 | 3 |
| SLC11A1 | KIR3DL2 | 0.710078 | 3 | 0 | 3 |
| SLC11A1 | SPSB4 | 0.700796 | 5 | 0 | 4 |
| SLC11A1 | KRTAP21-2 | 0.700349 | 3 | 0 | 3 |
For details and further investigation, click here
