| Full name: MAF bZIP transcription factor K | Alias Symbol: P18|NFE2U | ||
| Type: protein-coding gene | Cytoband: 7p22.3 | ||
| Entrez ID: 7975 | HGNC ID: HGNC:6782 | Ensembl Gene: ENSG00000198517 | OMIM ID: 600197 |
| Drug and gene relationship at DGIdb | |||
Expression of MAFK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAFK | 7975 | 226206_at | 0.3572 | 0.4748 | |
| GSE20347 | MAFK | 7975 | 206750_at | -0.0624 | 0.3227 | |
| GSE23400 | MAFK | 7975 | 206750_at | -0.0306 | 0.2738 | |
| GSE26886 | MAFK | 7975 | 226206_at | 0.5604 | 0.0570 | |
| GSE29001 | MAFK | 7975 | 206750_at | -0.1100 | 0.4836 | |
| GSE38129 | MAFK | 7975 | 206750_at | -0.0668 | 0.3090 | |
| GSE45670 | MAFK | 7975 | 226206_at | 0.1701 | 0.3677 | |
| GSE63941 | MAFK | 7975 | 226206_at | 0.3666 | 0.6460 | |
| GSE77861 | MAFK | 7975 | 226206_at | 1.3257 | 0.0012 | |
| GSE97050 | MAFK | 7975 | A_23_P373598 | -0.0869 | 0.7513 | |
| SRP007169 | MAFK | 7975 | RNAseq | 0.0319 | 0.9550 | |
| SRP008496 | MAFK | 7975 | RNAseq | 0.2869 | 0.4224 | |
| SRP064894 | MAFK | 7975 | RNAseq | 0.2392 | 0.3682 | |
| SRP133303 | MAFK | 7975 | RNAseq | 0.5340 | 0.0049 | |
| SRP159526 | MAFK | 7975 | RNAseq | -0.0547 | 0.8958 | |
| SRP193095 | MAFK | 7975 | RNAseq | 0.9061 | 0.0000 | |
| SRP219564 | MAFK | 7975 | RNAseq | 0.0206 | 0.9559 | |
| TCGA | MAFK | 7975 | RNAseq | -0.0229 | 0.6964 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MAFK expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MAFK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAFK | 7975 | 14 | 0 | 16 | |
| GSE20123 | MAFK | 7975 | 14 | 0 | 16 | |
| GSE43470 | MAFK | 7975 | 6 | 2 | 35 | |
| GSE46452 | MAFK | 7975 | 13 | 1 | 45 | |
| GSE47630 | MAFK | 7975 | 10 | 1 | 29 | |
| GSE54993 | MAFK | 7975 | 0 | 7 | 63 | |
| GSE54994 | MAFK | 7975 | 19 | 2 | 32 | |
| GSE60625 | MAFK | 7975 | 0 | 0 | 11 | |
| GSE74703 | MAFK | 7975 | 6 | 1 | 29 | |
| GSE74704 | MAFK | 7975 | 9 | 0 | 11 | |
| TCGA | MAFK | 7975 | 57 | 5 | 34 |
Total number of gains: 148; Total number of losses: 19; Total Number of normals: 321.
Somatic mutations of MAFK:
Generating mutation plots.
Highly correlated genes for MAFK:
Showing top 20/159 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAFK | SMYD4 | 0.755126 | 3 | 0 | 3 |
| MAFK | KCND3 | 0.714254 | 3 | 0 | 3 |
| MAFK | CACNA1H | 0.694282 | 3 | 0 | 3 |
| MAFK | CCDC106 | 0.691439 | 3 | 0 | 3 |
| MAFK | CGA | 0.678381 | 3 | 0 | 3 |
| MAFK | EDA | 0.675345 | 4 | 0 | 3 |
| MAFK | ELAVL3 | 0.675062 | 3 | 0 | 3 |
| MAFK | DRD2 | 0.674407 | 3 | 0 | 3 |
| MAFK | PRKCG | 0.672505 | 4 | 0 | 4 |
| MAFK | RHAG | 0.66493 | 3 | 0 | 3 |
| MAFK | ANKRD53 | 0.664679 | 3 | 0 | 3 |
| MAFK | LMF1 | 0.656928 | 3 | 0 | 3 |
| MAFK | RHOB | 0.647618 | 4 | 0 | 3 |
| MAFK | SDHA | 0.646561 | 3 | 0 | 3 |
| MAFK | GUCA1A | 0.642384 | 3 | 0 | 3 |
| MAFK | CCL16 | 0.639623 | 3 | 0 | 3 |
| MAFK | RASL10B | 0.635971 | 3 | 0 | 3 |
| MAFK | PPP2R5B | 0.635088 | 7 | 0 | 7 |
| MAFK | HSP90AA1 | 0.632946 | 4 | 0 | 3 |
| MAFK | SCUBE1 | 0.631346 | 3 | 0 | 3 |
For details and further investigation, click here
