| Full name: guanylate cyclase activator 1B | Alias Symbol: GCAP2|RP48 | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 2979 | HGNC ID: HGNC:4679 | Ensembl Gene: ENSG00000112599 | OMIM ID: 602275 |
| Drug and gene relationship at DGIdb | |||
Expression of GUCA1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GUCA1B | 2979 | 235528_at | -0.0857 | 0.8100 | |
| GSE20347 | GUCA1B | 2979 | 215841_at | -0.1931 | 0.0012 | |
| GSE23400 | GUCA1B | 2979 | 215841_at | -0.1887 | 0.0000 | |
| GSE26886 | GUCA1B | 2979 | 235528_at | -0.0437 | 0.8263 | |
| GSE29001 | GUCA1B | 2979 | 215841_at | -0.1993 | 0.1521 | |
| GSE38129 | GUCA1B | 2979 | 215841_at | -0.2283 | 0.0000 | |
| GSE45670 | GUCA1B | 2979 | 215841_at | 0.0071 | 0.9490 | |
| GSE53622 | GUCA1B | 2979 | 49504 | -0.0810 | 0.6880 | |
| GSE53624 | GUCA1B | 2979 | 49504 | -0.1819 | 0.2796 | |
| GSE63941 | GUCA1B | 2979 | 235528_at | 0.1622 | 0.4885 | |
| GSE77861 | GUCA1B | 2979 | 215841_at | -0.0920 | 0.5569 | |
| GSE97050 | GUCA1B | 2979 | A_23_P81825 | 0.0929 | 0.9181 | |
| SRP064894 | GUCA1B | 2979 | RNAseq | -0.4845 | 0.0320 | |
| SRP133303 | GUCA1B | 2979 | RNAseq | -0.3653 | 0.1572 | |
| SRP219564 | GUCA1B | 2979 | RNAseq | 0.4358 | 0.2909 | |
| TCGA | GUCA1B | 2979 | RNAseq | -0.2776 | 0.2138 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GUCA1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GUCA1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GUCA1B | 2979 | 7 | 0 | 23 | |
| GSE20123 | GUCA1B | 2979 | 7 | 0 | 23 | |
| GSE43470 | GUCA1B | 2979 | 6 | 0 | 37 | |
| GSE46452 | GUCA1B | 2979 | 2 | 9 | 48 | |
| GSE47630 | GUCA1B | 2979 | 8 | 4 | 28 | |
| GSE54993 | GUCA1B | 2979 | 3 | 2 | 65 | |
| GSE54994 | GUCA1B | 2979 | 11 | 4 | 38 | |
| GSE60625 | GUCA1B | 2979 | 0 | 1 | 10 | |
| GSE74703 | GUCA1B | 2979 | 6 | 0 | 30 | |
| GSE74704 | GUCA1B | 2979 | 3 | 0 | 17 | |
| TCGA | GUCA1B | 2979 | 20 | 13 | 63 |
Total number of gains: 73; Total number of losses: 33; Total Number of normals: 382.
Somatic mutations of GUCA1B:
Generating mutation plots.
Highly correlated genes for GUCA1B:
Showing top 20/592 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GUCA1B | VGF | 0.697126 | 4 | 0 | 3 |
| GUCA1B | OR1D2 | 0.690696 | 4 | 0 | 4 |
| GUCA1B | CRP | 0.688163 | 4 | 0 | 4 |
| GUCA1B | DSC3 | 0.679836 | 3 | 0 | 3 |
| GUCA1B | GRK1 | 0.674407 | 4 | 0 | 3 |
| GUCA1B | BFSP2 | 0.673262 | 4 | 0 | 4 |
| GUCA1B | HIVEP3 | 0.668846 | 4 | 0 | 3 |
| GUCA1B | IL18BP | 0.666593 | 5 | 0 | 4 |
| GUCA1B | CER1 | 0.665547 | 5 | 0 | 5 |
| GUCA1B | PRDM12 | 0.661787 | 6 | 0 | 5 |
| GUCA1B | MYBPC3 | 0.661602 | 5 | 0 | 4 |
| GUCA1B | TULP2 | 0.661296 | 4 | 0 | 3 |
| GUCA1B | CAMK1G | 0.659743 | 3 | 0 | 3 |
| GUCA1B | OR10J1 | 0.659345 | 5 | 0 | 4 |
| GUCA1B | HKDC1 | 0.658646 | 5 | 0 | 5 |
| GUCA1B | FOXH1 | 0.657602 | 3 | 0 | 3 |
| GUCA1B | OS9 | 0.656459 | 3 | 0 | 3 |
| GUCA1B | INO80B | 0.653918 | 3 | 0 | 3 |
| GUCA1B | RBFADN | 0.649601 | 4 | 0 | 3 |
| GUCA1B | NOS1 | 0.646851 | 4 | 0 | 3 |
For details and further investigation, click here
