| Full name: INO80 complex subunit B | Alias Symbol: HMGIYL4|PAPA-1|hIes2|PAP-1BP|IES2 | ||
| Type: protein-coding gene | Cytoband: 2p13.1 | ||
| Entrez ID: 83444 | HGNC ID: HGNC:13324 | Ensembl Gene: ENSG00000115274 | OMIM ID: 616456 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of INO80B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | INO80B | 83444 | 222093_s_at | 0.3006 | 0.1152 | |
| GSE20347 | INO80B | 83444 | 222093_s_at | 0.0441 | 0.6115 | |
| GSE23400 | INO80B | 83444 | 222093_s_at | -0.0922 | 0.0177 | |
| GSE26886 | INO80B | 83444 | 222093_s_at | 0.1411 | 0.2983 | |
| GSE29001 | INO80B | 83444 | 222093_s_at | -0.1955 | 0.2860 | |
| GSE38129 | INO80B | 83444 | 222093_s_at | 0.0760 | 0.4130 | |
| GSE45670 | INO80B | 83444 | 222093_s_at | 0.0075 | 0.9478 | |
| GSE63941 | INO80B | 83444 | 222093_s_at | 0.7692 | 0.0012 | |
| GSE77861 | INO80B | 83444 | 222093_s_at | 0.1396 | 0.4834 | |
| GSE97050 | INO80B | 83444 | A_23_P56673 | 0.3370 | 0.2544 | |
| SRP007169 | INO80B | 83444 | RNAseq | -0.7297 | 0.2093 | |
| SRP008496 | INO80B | 83444 | RNAseq | -0.8119 | 0.0028 | |
| SRP064894 | INO80B | 83444 | RNAseq | 0.0768 | 0.6973 | |
| SRP133303 | INO80B | 83444 | RNAseq | 0.0147 | 0.9404 | |
| SRP159526 | INO80B | 83444 | RNAseq | 0.2431 | 0.3924 | |
| SRP193095 | INO80B | 83444 | RNAseq | 0.2701 | 0.0657 | |
| SRP219564 | INO80B | 83444 | RNAseq | 0.1733 | 0.6643 | |
| TCGA | INO80B | 83444 | RNAseq | 0.1848 | 0.0090 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by INO80B expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of INO80B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | INO80B | 83444 | 9 | 2 | 19 | |
| GSE20123 | INO80B | 83444 | 11 | 1 | 18 | |
| GSE43470 | INO80B | 83444 | 4 | 0 | 39 | |
| GSE46452 | INO80B | 83444 | 2 | 3 | 54 | |
| GSE47630 | INO80B | 83444 | 7 | 0 | 33 | |
| GSE54993 | INO80B | 83444 | 0 | 6 | 64 | |
| GSE54994 | INO80B | 83444 | 10 | 0 | 43 | |
| GSE60625 | INO80B | 83444 | 0 | 3 | 8 | |
| GSE74703 | INO80B | 83444 | 4 | 0 | 32 | |
| GSE74704 | INO80B | 83444 | 8 | 0 | 12 | |
| TCGA | INO80B | 83444 | 37 | 2 | 57 |
Total number of gains: 92; Total number of losses: 17; Total Number of normals: 379.
Somatic mutations of INO80B:
Generating mutation plots.
Highly correlated genes for INO80B:
Showing top 20/919 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| INO80B | EXOSC5 | 0.824203 | 3 | 0 | 3 |
| INO80B | NUP35 | 0.822905 | 3 | 0 | 3 |
| INO80B | TOP1MT | 0.778974 | 3 | 0 | 3 |
| INO80B | TLCD1 | 0.770851 | 3 | 0 | 3 |
| INO80B | UBE2T | 0.768519 | 3 | 0 | 3 |
| INO80B | MAPK11 | 0.765696 | 3 | 0 | 3 |
| INO80B | MTBP | 0.756164 | 3 | 0 | 3 |
| INO80B | MED30 | 0.74806 | 3 | 0 | 3 |
| INO80B | C1orf131 | 0.746229 | 3 | 0 | 3 |
| INO80B | FANCM | 0.743579 | 3 | 0 | 3 |
| INO80B | MRPL21 | 0.738802 | 3 | 0 | 3 |
| INO80B | SZT2 | 0.735816 | 3 | 0 | 3 |
| INO80B | PHF5A | 0.734873 | 3 | 0 | 3 |
| INO80B | RUNX1-IT1 | 0.733124 | 3 | 0 | 3 |
| INO80B | NOP2 | 0.730908 | 4 | 0 | 4 |
| INO80B | MRPL38 | 0.730842 | 3 | 0 | 3 |
| INO80B | TREM2 | 0.729166 | 4 | 0 | 4 |
| INO80B | PMF1 | 0.727906 | 3 | 0 | 3 |
| INO80B | ITGA6 | 0.726892 | 3 | 0 | 3 |
| INO80B | GSS | 0.72108 | 4 | 0 | 3 |
For details and further investigation, click here
