| Full name: PR/SET domain 12 | Alias Symbol: PFM9 | ||
| Type: protein-coding gene | Cytoband: 9q34.12 | ||
| Entrez ID: 59335 | HGNC ID: HGNC:13997 | Ensembl Gene: ENSG00000130711 | OMIM ID: 616458 |
| Drug and gene relationship at DGIdb | |||
Expression of PRDM12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRDM12 | 59335 | 220894_x_at | -0.3715 | 0.2311 | |
| GSE20347 | PRDM12 | 59335 | 220894_x_at | -0.3456 | 0.0008 | |
| GSE23400 | PRDM12 | 59335 | 220894_x_at | -0.3386 | 0.0000 | |
| GSE26886 | PRDM12 | 59335 | 220894_x_at | 0.1130 | 0.4161 | |
| GSE29001 | PRDM12 | 59335 | 220894_x_at | -0.4060 | 0.0079 | |
| GSE38129 | PRDM12 | 59335 | 220894_x_at | -0.5124 | 0.0000 | |
| GSE45670 | PRDM12 | 59335 | 220894_x_at | 0.0898 | 0.6149 | |
| GSE53622 | PRDM12 | 59335 | 4152 | 0.2660 | 0.0168 | |
| GSE53624 | PRDM12 | 59335 | 4152 | 1.2150 | 0.0000 | |
| GSE63941 | PRDM12 | 59335 | 220894_x_at | 0.1434 | 0.4312 | |
| GSE77861 | PRDM12 | 59335 | 220894_x_at | -0.2819 | 0.1360 | |
| TCGA | PRDM12 | 59335 | RNAseq | 1.8878 | 0.0035 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by PRDM12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRDM12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRDM12 | 59335 | 6 | 9 | 15 | |
| GSE20123 | PRDM12 | 59335 | 6 | 9 | 15 | |
| GSE43470 | PRDM12 | 59335 | 5 | 7 | 31 | |
| GSE46452 | PRDM12 | 59335 | 6 | 13 | 40 | |
| GSE47630 | PRDM12 | 59335 | 3 | 16 | 21 | |
| GSE54993 | PRDM12 | 59335 | 3 | 3 | 64 | |
| GSE54994 | PRDM12 | 59335 | 12 | 9 | 32 | |
| GSE60625 | PRDM12 | 59335 | 0 | 0 | 11 | |
| GSE74703 | PRDM12 | 59335 | 5 | 5 | 26 | |
| GSE74704 | PRDM12 | 59335 | 3 | 7 | 10 | |
| TCGA | PRDM12 | 59335 | 27 | 26 | 43 |
Total number of gains: 76; Total number of losses: 104; Total Number of normals: 308.
Somatic mutations of PRDM12:
Generating mutation plots.
Highly correlated genes for PRDM12:
Showing top 20/534 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRDM12 | SNX11 | 0.703438 | 3 | 0 | 3 |
| PRDM12 | KRTAP5-9 | 0.699783 | 3 | 0 | 3 |
| PRDM12 | MYL4 | 0.68915 | 7 | 0 | 7 |
| PRDM12 | PRAM1 | 0.68061 | 3 | 0 | 3 |
| PRDM12 | HUS1B | 0.677369 | 4 | 0 | 4 |
| PRDM12 | GTF3C1 | 0.6765 | 3 | 0 | 3 |
| PRDM12 | TM6SF2 | 0.672551 | 4 | 0 | 3 |
| PRDM12 | ZNF835 | 0.670366 | 5 | 0 | 4 |
| PRDM12 | RASSF7 | 0.668243 | 6 | 0 | 6 |
| PRDM12 | CPNE7 | 0.666368 | 4 | 0 | 3 |
| PRDM12 | ITGB7 | 0.663292 | 5 | 0 | 4 |
| PRDM12 | APOA4 | 0.6618 | 5 | 0 | 3 |
| PRDM12 | GUCA1B | 0.661787 | 6 | 0 | 5 |
| PRDM12 | GJC2 | 0.657136 | 5 | 0 | 4 |
| PRDM12 | NPEPL1 | 0.656263 | 5 | 0 | 5 |
| PRDM12 | FGF21 | 0.653853 | 5 | 0 | 4 |
| PRDM12 | SELP | 0.652752 | 4 | 0 | 4 |
| PRDM12 | KLHL17 | 0.648555 | 3 | 0 | 3 |
| PRDM12 | RBP4 | 0.643937 | 3 | 0 | 3 |
| PRDM12 | ZNF552 | 0.643008 | 5 | 0 | 5 |
For details and further investigation, click here
