| Full name: acid phosphatase 5, tartrate resistant | Alias Symbol: TRAP|HPAP | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 54 | HGNC ID: HGNC:124 | Ensembl Gene: ENSG00000102575 | OMIM ID: 171640 |
| Drug and gene relationship at DGIdb | |||
Expression of ACP5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACP5 | 54 | 204638_at | 0.5595 | 0.5102 | |
| GSE20347 | ACP5 | 54 | 204638_at | -0.2229 | 0.2739 | |
| GSE23400 | ACP5 | 54 | 204638_at | 0.3380 | 0.0060 | |
| GSE26886 | ACP5 | 54 | 204638_at | 0.3819 | 0.2678 | |
| GSE29001 | ACP5 | 54 | 204638_at | -0.1142 | 0.7213 | |
| GSE38129 | ACP5 | 54 | 204638_at | 0.3122 | 0.2323 | |
| GSE45670 | ACP5 | 54 | 204638_at | 0.5485 | 0.0089 | |
| GSE53622 | ACP5 | 54 | 10759 | 0.0931 | 0.1078 | |
| GSE53624 | ACP5 | 54 | 10759 | 0.1938 | 0.0007 | |
| GSE63941 | ACP5 | 54 | 204638_at | 0.5421 | 0.5846 | |
| GSE77861 | ACP5 | 54 | 204638_at | -0.2125 | 0.5692 | |
| GSE97050 | ACP5 | 54 | A_23_P142075 | 0.2179 | 0.4689 | |
| SRP007169 | ACP5 | 54 | RNAseq | 0.3076 | 0.6228 | |
| SRP008496 | ACP5 | 54 | RNAseq | -0.0379 | 0.9179 | |
| SRP064894 | ACP5 | 54 | RNAseq | 1.4541 | 0.0000 | |
| SRP133303 | ACP5 | 54 | RNAseq | 0.9686 | 0.0001 | |
| SRP159526 | ACP5 | 54 | RNAseq | 0.3408 | 0.6400 | |
| SRP193095 | ACP5 | 54 | RNAseq | 0.5699 | 0.0001 | |
| SRP219564 | ACP5 | 54 | RNAseq | 1.0338 | 0.0708 | |
| TCGA | ACP5 | 54 | RNAseq | 0.2335 | 0.0218 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ACP5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACP5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACP5 | 54 | 4 | 2 | 24 | |
| GSE20123 | ACP5 | 54 | 3 | 1 | 26 | |
| GSE43470 | ACP5 | 54 | 2 | 6 | 35 | |
| GSE46452 | ACP5 | 54 | 47 | 1 | 11 | |
| GSE47630 | ACP5 | 54 | 4 | 7 | 29 | |
| GSE54993 | ACP5 | 54 | 16 | 3 | 51 | |
| GSE54994 | ACP5 | 54 | 6 | 13 | 34 | |
| GSE60625 | ACP5 | 54 | 9 | 0 | 2 | |
| GSE74703 | ACP5 | 54 | 2 | 4 | 30 | |
| GSE74704 | ACP5 | 54 | 0 | 1 | 19 | |
| TCGA | ACP5 | 54 | 16 | 12 | 68 |
Total number of gains: 109; Total number of losses: 50; Total Number of normals: 329.
Somatic mutations of ACP5:
Generating mutation plots.
Highly correlated genes for ACP5:
Showing top 20/52 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACP5 | GZMM | 0.745737 | 3 | 0 | 3 |
| ACP5 | SPACA3 | 0.74358 | 3 | 0 | 3 |
| ACP5 | BCL6B | 0.737215 | 3 | 0 | 3 |
| ACP5 | C14orf180 | 0.724102 | 3 | 0 | 3 |
| ACP5 | MYO10 | 0.702888 | 4 | 0 | 3 |
| ACP5 | SLC22A31 | 0.69058 | 3 | 0 | 3 |
| ACP5 | HAPLN3 | 0.688165 | 3 | 0 | 3 |
| ACP5 | HCK | 0.681376 | 4 | 0 | 3 |
| ACP5 | ATP8B3 | 0.668766 | 3 | 0 | 3 |
| ACP5 | HOTAIR | 0.66539 | 3 | 0 | 3 |
| ACP5 | KIF4A | 0.643178 | 4 | 0 | 3 |
| ACP5 | PTK2B | 0.631812 | 4 | 0 | 3 |
| ACP5 | PCYOX1L | 0.612904 | 4 | 0 | 3 |
| ACP5 | SLC22A4 | 0.612104 | 3 | 0 | 3 |
| ACP5 | UBE2S | 0.607715 | 4 | 0 | 3 |
| ACP5 | FFAR2 | 0.605107 | 4 | 0 | 3 |
| ACP5 | CPNE7 | 0.595778 | 4 | 0 | 3 |
| ACP5 | OR7A17 | 0.587503 | 4 | 0 | 3 |
| ACP5 | HK3 | 0.58744 | 7 | 0 | 4 |
| ACP5 | LST1 | 0.585159 | 4 | 0 | 3 |
For details and further investigation, click here
