RLN3

 

Full name: relaxin 3 Alias Symbol: ZINS4|RXN3|H3
Type: protein-coding gene Cytoband: 19p13.2
Entrez ID: 117579 HGNC ID: HGNC:17135 Ensembl Gene:  OMIM ID: 606855
Drug and gene relationship at DGIdb

 

Expression of RLN3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RLN3 117579 1553403_at 0.1392 0.6103
GSE26886 RLN3 117579 1553403_at 0.0179 0.8747
GSE45670 RLN3 117579 1553403_at 0.1410 0.0632
GSE63941 RLN3 117579 1553403_at 0.1526 0.3597
GSE77861 RLN3 117579 1553403_at -0.0054 0.9781
GSE97050 RLN3 117579 A_33_P3226825 0.2722 0.2885

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by RLN3 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of RLN3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RLN3 117579 4 2 24
GSE20123 RLN3 117579 3 1 26
GSE43470 RLN3 117579 2 6 35
GSE46452 RLN3 117579 47 1 11
GSE47630 RLN3 117579 4 7 29
GSE54993 RLN3 117579 15 4 51
GSE54994 RLN3 117579 6 13 34
GSE60625 RLN3 117579 9 0 2
GSE74703 RLN3 117579 2 4 30
GSE74704 RLN3 117579 0 1 19
TCGA RLN3 117579 21 11 64

Total number of gains: 113; Total number of losses: 50; Total Number of normals: 325.  


 

Somatic mutations of RLN3:

 

Generating mutation plots.

 

Highly correlated genes for RLN3:

 

Showing top 20/128 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RLN3UPK3A0.817264303
RLN3FMR1NB0.804467303
RLN3LRFN40.797161303
RLN3VMO10.780558303
RLN3CALCA0.779334303
RLN3NPAS10.777084303
RLN3SUN50.772061303
RLN3OSBPL50.768016303
RLN3POLL0.75792303
RLN3KLK20.757005303
RLN3LHX10.7529303
RLN3GZMM0.747332303
RLN3GPR1500.74161303
RLN3SLC39A50.738879403
RLN3MAPK8IP20.736623303
RLN3NPPB0.725521403
RLN3TEX13B0.724124404
RLN3IGFN10.719628303
RLN3ABCA20.717982303
RLN3DNAH90.712246303

For details and further investigation, click here