| Full name: hyaluronan and proteoglycan link protein 4 | Alias Symbol: BRAL2|KIAA1926 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 404037 | HGNC ID: HGNC:31357 | Ensembl Gene: ENSG00000187664 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HAPLN4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HAPLN4 | 404037 | 235420_at | -0.2448 | 0.3377 | |
| GSE26886 | HAPLN4 | 404037 | 235420_at | 0.1071 | 0.4783 | |
| GSE45670 | HAPLN4 | 404037 | 235420_at | -0.0037 | 0.9672 | |
| GSE63941 | HAPLN4 | 404037 | 235420_at | -0.0686 | 0.6815 | |
| GSE77861 | HAPLN4 | 404037 | 235420_at | -0.1020 | 0.5592 | |
| GSE97050 | HAPLN4 | 404037 | A_23_P430842 | 0.1287 | 0.5842 | |
| SRP064894 | HAPLN4 | 404037 | RNAseq | 0.5106 | 0.0400 | |
| SRP133303 | HAPLN4 | 404037 | RNAseq | 0.1026 | 0.4009 | |
| SRP193095 | HAPLN4 | 404037 | RNAseq | -0.2902 | 0.0740 | |
| SRP219564 | HAPLN4 | 404037 | RNAseq | 0.2892 | 0.4906 | |
| TCGA | HAPLN4 | 404037 | RNAseq | 0.3652 | 0.3851 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HAPLN4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of HAPLN4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HAPLN4 | 404037 | 4 | 5 | 21 | |
| GSE20123 | HAPLN4 | 404037 | 3 | 3 | 24 | |
| GSE43470 | HAPLN4 | 404037 | 2 | 5 | 36 | |
| GSE46452 | HAPLN4 | 404037 | 47 | 1 | 11 | |
| GSE47630 | HAPLN4 | 404037 | 5 | 8 | 27 | |
| GSE54993 | HAPLN4 | 404037 | 16 | 4 | 50 | |
| GSE54994 | HAPLN4 | 404037 | 6 | 13 | 34 | |
| GSE60625 | HAPLN4 | 404037 | 9 | 0 | 2 | |
| GSE74703 | HAPLN4 | 404037 | 2 | 3 | 31 | |
| GSE74704 | HAPLN4 | 404037 | 0 | 3 | 17 | |
| TCGA | HAPLN4 | 404037 | 16 | 10 | 70 |
Total number of gains: 110; Total number of losses: 55; Total Number of normals: 323.
Somatic mutations of HAPLN4:
Generating mutation plots.
Highly correlated genes for HAPLN4:
Showing top 20/26 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HAPLN4 | CASS4 | 0.664242 | 4 | 0 | 3 |
| HAPLN4 | ADAP1 | 0.618088 | 3 | 0 | 3 |
| HAPLN4 | LENG1 | 0.6097 | 3 | 0 | 3 |
| HAPLN4 | WDR87 | 0.597858 | 3 | 0 | 3 |
| HAPLN4 | PRSS37 | 0.584692 | 3 | 0 | 3 |
| HAPLN4 | SLA2 | 0.571112 | 3 | 0 | 3 |
| HAPLN4 | F2RL3 | 0.566248 | 3 | 0 | 3 |
| HAPLN4 | HNF1B | 0.564894 | 3 | 0 | 3 |
| HAPLN4 | PARP10 | 0.56416 | 4 | 0 | 4 |
| HAPLN4 | KRTAP3-1 | 0.563146 | 3 | 0 | 3 |
| HAPLN4 | PRSS54 | 0.562165 | 4 | 0 | 3 |
| HAPLN4 | C22orf23 | 0.549957 | 4 | 0 | 3 |
| HAPLN4 | FNDC9 | 0.542482 | 3 | 0 | 3 |
| HAPLN4 | OR6B1 | 0.542116 | 3 | 0 | 3 |
| HAPLN4 | FSIP1 | 0.540876 | 4 | 0 | 3 |
| HAPLN4 | SPINT3 | 0.526323 | 3 | 0 | 3 |
| HAPLN4 | FFAR1 | 0.522797 | 4 | 0 | 3 |
| HAPLN4 | CABP4 | 0.522678 | 4 | 0 | 3 |
| HAPLN4 | OTOF | 0.52093 | 4 | 0 | 3 |
| HAPLN4 | TNFSF11 | 0.520409 | 4 | 0 | 3 |
For details and further investigation, click here
