| Full name: olfactory receptor family 6 subfamily B member 1 | Alias Symbol: OR7-3 | ||
| Type: protein-coding gene | Cytoband: 7q35 | ||
| Entrez ID: 135946 | HGNC ID: HGNC:8354 | Ensembl Gene: ENSG00000221813 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
OR6B1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04740 | Olfactory transduction |
Expression of OR6B1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OR6B1 | 135946 | 234363_at | -0.2637 | 0.2442 | |
| GSE26886 | OR6B1 | 135946 | 234363_at | -0.0879 | 0.4159 | |
| GSE45670 | OR6B1 | 135946 | 234363_at | 0.1012 | 0.3782 | |
| GSE53622 | OR6B1 | 135946 | 60315 | 0.1471 | 0.1765 | |
| GSE53624 | OR6B1 | 135946 | 60315 | 0.3809 | 0.0002 | |
| GSE63941 | OR6B1 | 135946 | 234363_at | -0.1281 | 0.1881 | |
| GSE77861 | OR6B1 | 135946 | 234363_at | -0.2751 | 0.0316 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OR6B1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OR6B1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OR6B1 | 135946 | 3 | 2 | 25 | |
| GSE20123 | OR6B1 | 135946 | 3 | 2 | 25 | |
| GSE43470 | OR6B1 | 135946 | 3 | 4 | 36 | |
| GSE46452 | OR6B1 | 135946 | 7 | 2 | 50 | |
| GSE47630 | OR6B1 | 135946 | 6 | 8 | 26 | |
| GSE54993 | OR6B1 | 135946 | 3 | 4 | 63 | |
| GSE54994 | OR6B1 | 135946 | 5 | 8 | 40 | |
| GSE60625 | OR6B1 | 135946 | 0 | 0 | 11 | |
| GSE74703 | OR6B1 | 135946 | 2 | 4 | 30 | |
| GSE74704 | OR6B1 | 135946 | 1 | 2 | 17 | |
| TCGA | OR6B1 | 135946 | 27 | 26 | 43 |
Total number of gains: 60; Total number of losses: 62; Total Number of normals: 366.
Somatic mutations of OR6B1:
Generating mutation plots.
Highly correlated genes for OR6B1:
Showing top 20/49 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OR6B1 | HRC | 0.711184 | 3 | 0 | 3 |
| OR6B1 | L1CAM | 0.702492 | 3 | 0 | 3 |
| OR6B1 | SORBS2 | 0.684822 | 3 | 0 | 3 |
| OR6B1 | CASC17 | 0.676179 | 3 | 0 | 3 |
| OR6B1 | PLCD4 | 0.66432 | 3 | 0 | 3 |
| OR6B1 | CNGA3 | 0.653069 | 3 | 0 | 3 |
| OR6B1 | ASB17 | 0.647997 | 4 | 0 | 4 |
| OR6B1 | SMPX | 0.636543 | 3 | 0 | 3 |
| OR6B1 | AKAP14 | 0.636389 | 3 | 0 | 3 |
| OR6B1 | ARHGEF10L | 0.634689 | 3 | 0 | 3 |
| OR6B1 | THPO | 0.630035 | 3 | 0 | 3 |
| OR6B1 | CA1 | 0.62946 | 3 | 0 | 3 |
| OR6B1 | CH25H | 0.628122 | 3 | 0 | 3 |
| OR6B1 | LMNTD1 | 0.626512 | 3 | 0 | 3 |
| OR6B1 | SMTNL2 | 0.62517 | 3 | 0 | 3 |
| OR6B1 | AMOTL1 | 0.615206 | 3 | 0 | 3 |
| OR6B1 | DLGAP2 | 0.605996 | 3 | 0 | 3 |
| OR6B1 | HPYR1 | 0.603094 | 3 | 0 | 3 |
| OR6B1 | VGLL2 | 0.596197 | 4 | 0 | 3 |
| OR6B1 | SAMD15 | 0.595605 | 3 | 0 | 3 |
For details and further investigation, click here
