| Full name: serine protease 54 | Alias Symbol: FLJ25339|KLKBL4|CT67 | ||
| Type: protein-coding gene | Cytoband: 16q21 | ||
| Entrez ID: 221191 | HGNC ID: HGNC:26336 | Ensembl Gene: ENSG00000103023 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PRSS54:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRSS54 | 221191 | 231287_s_at | -0.1633 | 0.4865 | |
| GSE26886 | PRSS54 | 221191 | 231287_s_at | 0.0879 | 0.4778 | |
| GSE45670 | PRSS54 | 221191 | 231287_s_at | 0.1485 | 0.0386 | |
| GSE63941 | PRSS54 | 221191 | 231287_s_at | 0.3161 | 0.0843 | |
| GSE77861 | PRSS54 | 221191 | 231287_s_at | -0.1484 | 0.2215 | |
| GSE97050 | PRSS54 | 221191 | A_23_P88776 | 0.1429 | 0.5102 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PRSS54 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of PRSS54:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRSS54 | 221191 | 7 | 0 | 23 | |
| GSE20123 | PRSS54 | 221191 | 7 | 0 | 23 | |
| GSE43470 | PRSS54 | 221191 | 2 | 7 | 34 | |
| GSE46452 | PRSS54 | 221191 | 38 | 1 | 20 | |
| GSE47630 | PRSS54 | 221191 | 10 | 8 | 22 | |
| GSE54993 | PRSS54 | 221191 | 2 | 4 | 64 | |
| GSE54994 | PRSS54 | 221191 | 6 | 10 | 37 | |
| GSE60625 | PRSS54 | 221191 | 4 | 0 | 7 | |
| GSE74703 | PRSS54 | 221191 | 2 | 5 | 29 | |
| GSE74704 | PRSS54 | 221191 | 5 | 0 | 15 | |
| TCGA | PRSS54 | 221191 | 26 | 11 | 59 |
Total number of gains: 109; Total number of losses: 46; Total Number of normals: 333.
Somatic mutations of PRSS54:
Generating mutation plots.
Highly correlated genes for PRSS54:
Showing top 20/95 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRSS54 | CTSE | 0.742657 | 3 | 0 | 3 |
| PRSS54 | IL26 | 0.731379 | 3 | 0 | 3 |
| PRSS54 | EPB42 | 0.72276 | 3 | 0 | 3 |
| PRSS54 | MEGF11 | 0.722056 | 3 | 0 | 3 |
| PRSS54 | SRCIN1 | 0.712424 | 3 | 0 | 3 |
| PRSS54 | CNPY1 | 0.697595 | 3 | 0 | 3 |
| PRSS54 | SEMA5B | 0.695566 | 3 | 0 | 3 |
| PRSS54 | TERT | 0.694735 | 3 | 0 | 3 |
| PRSS54 | MUC2 | 0.692047 | 4 | 0 | 3 |
| PRSS54 | PRG2 | 0.688327 | 4 | 0 | 3 |
| PRSS54 | ZGLP1 | 0.683746 | 4 | 0 | 3 |
| PRSS54 | SLC6A13 | 0.672757 | 3 | 0 | 3 |
| PRSS54 | CLEC4G | 0.671035 | 3 | 0 | 3 |
| PRSS54 | SLC22A8 | 0.664258 | 4 | 0 | 3 |
| PRSS54 | HPX | 0.660257 | 3 | 0 | 3 |
| PRSS54 | RGR | 0.656761 | 4 | 0 | 3 |
| PRSS54 | FRMD1 | 0.651083 | 3 | 0 | 3 |
| PRSS54 | SHANK1 | 0.64922 | 3 | 0 | 3 |
| PRSS54 | FFAR2 | 0.648465 | 3 | 0 | 3 |
| PRSS54 | OSM | 0.648071 | 4 | 0 | 3 |
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