| Full name: chloride voltage-gated channel Ka | Alias Symbol: hClC-Ka | ||
| Type: protein-coding gene | Cytoband: 1p36.13 | ||
| Entrez ID: 1187 | HGNC ID: HGNC:2026 | Ensembl Gene: ENSG00000186510 | OMIM ID: 602024 |
| Drug and gene relationship at DGIdb | |||
Expression of CLCNKA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | CLCNKA | 1187 | 52973 | -0.1199 | 0.2743 | |
| GSE53624 | CLCNKA | 1187 | 52973 | 0.0152 | 0.8687 | |
| GSE97050 | CLCNKA | 1187 | A_24_P2361 | -0.1151 | 0.7877 | |
| TCGA | CLCNKA | 1187 | RNAseq | -4.5028 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CLCNKA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLCNKA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLCNKA | 1187 | 1 | 5 | 24 | |
| GSE20123 | CLCNKA | 1187 | 1 | 4 | 25 | |
| GSE43470 | CLCNKA | 1187 | 1 | 8 | 34 | |
| GSE46452 | CLCNKA | 1187 | 7 | 1 | 51 | |
| GSE47630 | CLCNKA | 1187 | 8 | 3 | 29 | |
| GSE54993 | CLCNKA | 1187 | 3 | 1 | 66 | |
| GSE54994 | CLCNKA | 1187 | 10 | 4 | 39 | |
| GSE60625 | CLCNKA | 1187 | 0 | 0 | 11 | |
| GSE74703 | CLCNKA | 1187 | 1 | 5 | 30 | |
| GSE74704 | CLCNKA | 1187 | 1 | 0 | 19 | |
| TCGA | CLCNKA | 1187 | 12 | 23 | 61 |
Total number of gains: 45; Total number of losses: 54; Total Number of normals: 389.
Somatic mutations of CLCNKA:
Generating mutation plots.
Highly correlated genes for CLCNKA:
Showing top 20/67 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLCNKA | NPPA | 0.847382 | 3 | 0 | 3 |
| CLCNKA | TMEM229A | 0.836533 | 3 | 0 | 3 |
| CLCNKA | AQP4 | 0.812535 | 3 | 0 | 3 |
| CLCNKA | SPACA1 | 0.80566 | 3 | 0 | 3 |
| CLCNKA | HGD | 0.801956 | 3 | 0 | 3 |
| CLCNKA | USH1C | 0.796004 | 3 | 0 | 3 |
| CLCNKA | SCGN | 0.783403 | 3 | 0 | 3 |
| CLCNKA | FOXA3 | 0.768043 | 3 | 0 | 3 |
| CLCNKA | KCNQ4 | 0.759808 | 3 | 0 | 3 |
| CLCNKA | CRYGN | 0.75592 | 3 | 0 | 3 |
| CLCNKA | PGP | 0.751218 | 3 | 0 | 3 |
| CLCNKA | SHISA8 | 0.749052 | 3 | 0 | 3 |
| CLCNKA | MUC2 | 0.743285 | 3 | 0 | 3 |
| CLCNKA | SLC5A5 | 0.742921 | 3 | 0 | 3 |
| CLCNKA | SHISA7 | 0.741778 | 3 | 0 | 3 |
| CLCNKA | PALM3 | 0.739866 | 3 | 0 | 3 |
| CLCNKA | ZNF329 | 0.737067 | 3 | 0 | 3 |
| CLCNKA | SORCS3 | 0.734289 | 3 | 0 | 3 |
| CLCNKA | PRR18 | 0.732764 | 3 | 0 | 3 |
| CLCNKA | HCRTR1 | 0.732716 | 3 | 0 | 3 |
For details and further investigation, click here
