| Full name: F-box protein 28 | Alias Symbol: FLJ10766|KIAA0483|Fbx28|CENP-30 | ||
| Type: protein-coding gene | Cytoband: 1q42.11 | ||
| Entrez ID: 23219 | HGNC ID: HGNC:29046 | Ensembl Gene: ENSG00000143756 | OMIM ID: 609100 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXO28:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXO28 | 23219 | 202271_at | -0.0719 | 0.7871 | |
| GSE20347 | FBXO28 | 23219 | 202271_at | -0.2664 | 0.0546 | |
| GSE23400 | FBXO28 | 23219 | 202271_at | 0.0988 | 0.1990 | |
| GSE26886 | FBXO28 | 23219 | 202271_at | -0.3207 | 0.2633 | |
| GSE29001 | FBXO28 | 23219 | 202271_at | -0.0563 | 0.8808 | |
| GSE38129 | FBXO28 | 23219 | 202271_at | -0.2425 | 0.0242 | |
| GSE45670 | FBXO28 | 23219 | 202271_at | -0.0863 | 0.5826 | |
| GSE53622 | FBXO28 | 23219 | 64397 | 0.0035 | 0.9599 | |
| GSE53624 | FBXO28 | 23219 | 23509 | -0.2806 | 0.0001 | |
| GSE63941 | FBXO28 | 23219 | 1555971_s_at | 1.0147 | 0.0091 | |
| GSE77861 | FBXO28 | 23219 | 202271_at | 0.0843 | 0.8118 | |
| GSE97050 | FBXO28 | 23219 | A_23_P137578 | -0.0168 | 0.9429 | |
| SRP007169 | FBXO28 | 23219 | RNAseq | -0.9344 | 0.0294 | |
| SRP008496 | FBXO28 | 23219 | RNAseq | -0.8109 | 0.0015 | |
| SRP064894 | FBXO28 | 23219 | RNAseq | -0.4639 | 0.0152 | |
| SRP133303 | FBXO28 | 23219 | RNAseq | 0.1278 | 0.3938 | |
| SRP159526 | FBXO28 | 23219 | RNAseq | -0.2376 | 0.5492 | |
| SRP193095 | FBXO28 | 23219 | RNAseq | -0.2023 | 0.0535 | |
| SRP219564 | FBXO28 | 23219 | RNAseq | -0.4676 | 0.1786 | |
| TCGA | FBXO28 | 23219 | RNAseq | 0.0445 | 0.3368 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FBXO28 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXO28:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXO28 | 23219 | 10 | 0 | 20 | |
| GSE20123 | FBXO28 | 23219 | 10 | 0 | 20 | |
| GSE43470 | FBXO28 | 23219 | 7 | 0 | 36 | |
| GSE46452 | FBXO28 | 23219 | 3 | 1 | 55 | |
| GSE47630 | FBXO28 | 23219 | 15 | 0 | 25 | |
| GSE54993 | FBXO28 | 23219 | 0 | 6 | 64 | |
| GSE54994 | FBXO28 | 23219 | 16 | 0 | 37 | |
| GSE60625 | FBXO28 | 23219 | 0 | 0 | 11 | |
| GSE74703 | FBXO28 | 23219 | 7 | 0 | 29 | |
| GSE74704 | FBXO28 | 23219 | 4 | 0 | 16 | |
| TCGA | FBXO28 | 23219 | 45 | 4 | 47 |
Total number of gains: 117; Total number of losses: 11; Total Number of normals: 360.
Somatic mutations of FBXO28:
Generating mutation plots.
Highly correlated genes for FBXO28:
Showing top 20/404 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXO28 | RBM26 | 0.7851 | 3 | 0 | 3 |
| FBXO28 | HEATR5A | 0.766253 | 3 | 0 | 3 |
| FBXO28 | ACSL1 | 0.762803 | 3 | 0 | 3 |
| FBXO28 | ANKRD13C | 0.759935 | 3 | 0 | 3 |
| FBXO28 | PCNP | 0.751306 | 3 | 0 | 3 |
| FBXO28 | ZFX | 0.739675 | 3 | 0 | 3 |
| FBXO28 | LCOR | 0.728484 | 3 | 0 | 3 |
| FBXO28 | PRCC | 0.725712 | 3 | 0 | 3 |
| FBXO28 | RNASEL | 0.725665 | 3 | 0 | 3 |
| FBXO28 | PNO1 | 0.723863 | 3 | 0 | 3 |
| FBXO28 | SNX4 | 0.721406 | 3 | 0 | 3 |
| FBXO28 | THYN1 | 0.720794 | 3 | 0 | 3 |
| FBXO28 | RASA2 | 0.719654 | 3 | 0 | 3 |
| FBXO28 | DRAM2 | 0.715179 | 3 | 0 | 3 |
| FBXO28 | FH | 0.710769 | 3 | 0 | 3 |
| FBXO28 | ST13 | 0.70728 | 3 | 0 | 3 |
| FBXO28 | COX15 | 0.706606 | 4 | 0 | 4 |
| FBXO28 | TTI2 | 0.703385 | 3 | 0 | 3 |
| FBXO28 | USP38 | 0.700746 | 3 | 0 | 3 |
| FBXO28 | CYCS | 0.697679 | 3 | 0 | 3 |
For details and further investigation, click here
