| Full name: fukutin | Alias Symbol: LGMD2M | ||
| Type: protein-coding gene | Cytoband: 9q31.2 | ||
| Entrez ID: 2218 | HGNC ID: HGNC:3622 | Ensembl Gene: ENSG00000106692 | OMIM ID: 607440 |
| Drug and gene relationship at DGIdb | |||
Expression of FKTN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FKTN | 2218 | 205283_at | 0.3375 | 0.3685 | |
| GSE20347 | FKTN | 2218 | 205283_at | -0.1679 | 0.2255 | |
| GSE23400 | FKTN | 2218 | 205283_at | 0.0636 | 0.2979 | |
| GSE26886 | FKTN | 2218 | 205283_at | 0.4082 | 0.1134 | |
| GSE29001 | FKTN | 2218 | 205283_at | 0.3248 | 0.2704 | |
| GSE38129 | FKTN | 2218 | 205283_at | -0.0440 | 0.7834 | |
| GSE45670 | FKTN | 2218 | 205283_at | -0.1614 | 0.4781 | |
| GSE53622 | FKTN | 2218 | 52492 | 0.4826 | 0.0000 | |
| GSE53624 | FKTN | 2218 | 52492 | 0.5321 | 0.0000 | |
| GSE63941 | FKTN | 2218 | 205283_at | -0.3702 | 0.6353 | |
| GSE77861 | FKTN | 2218 | 205283_at | -0.0032 | 0.9951 | |
| GSE97050 | FKTN | 2218 | A_33_P3259092 | 0.4685 | 0.1659 | |
| SRP007169 | FKTN | 2218 | RNAseq | 0.6398 | 0.2104 | |
| SRP008496 | FKTN | 2218 | RNAseq | 0.7604 | 0.0074 | |
| SRP064894 | FKTN | 2218 | RNAseq | 0.1089 | 0.5374 | |
| SRP133303 | FKTN | 2218 | RNAseq | 0.2124 | 0.3488 | |
| SRP159526 | FKTN | 2218 | RNAseq | 0.0004 | 0.9985 | |
| SRP193095 | FKTN | 2218 | RNAseq | 0.0738 | 0.4111 | |
| SRP219564 | FKTN | 2218 | RNAseq | 0.1409 | 0.5059 | |
| TCGA | FKTN | 2218 | RNAseq | -0.0769 | 0.1680 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FKTN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FKTN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FKTN | 2218 | 4 | 10 | 16 | |
| GSE20123 | FKTN | 2218 | 5 | 9 | 16 | |
| GSE43470 | FKTN | 2218 | 7 | 3 | 33 | |
| GSE46452 | FKTN | 2218 | 6 | 13 | 40 | |
| GSE47630 | FKTN | 2218 | 1 | 17 | 22 | |
| GSE54993 | FKTN | 2218 | 3 | 3 | 64 | |
| GSE54994 | FKTN | 2218 | 9 | 10 | 34 | |
| GSE60625 | FKTN | 2218 | 0 | 0 | 11 | |
| GSE74703 | FKTN | 2218 | 6 | 3 | 27 | |
| GSE74704 | FKTN | 2218 | 2 | 6 | 12 | |
| TCGA | FKTN | 2218 | 26 | 21 | 49 |
Total number of gains: 69; Total number of losses: 95; Total Number of normals: 324.
Somatic mutations of FKTN:
Generating mutation plots.
Highly correlated genes for FKTN:
Showing top 20/450 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FKTN | ITGB8 | 0.831056 | 3 | 0 | 3 |
| FKTN | ERP27 | 0.809451 | 3 | 0 | 3 |
| FKTN | SLC44A4 | 0.806331 | 3 | 0 | 3 |
| FKTN | C2orf69 | 0.794543 | 3 | 0 | 3 |
| FKTN | RNPS1 | 0.780484 | 3 | 0 | 3 |
| FKTN | ASCC3 | 0.778301 | 3 | 0 | 3 |
| FKTN | FAM171B | 0.761032 | 3 | 0 | 3 |
| FKTN | NPNT | 0.735723 | 3 | 0 | 3 |
| FKTN | BAD | 0.73113 | 3 | 0 | 3 |
| FKTN | PARP16 | 0.729454 | 3 | 0 | 3 |
| FKTN | ANAPC4 | 0.727212 | 3 | 0 | 3 |
| FKTN | MOGS | 0.726424 | 3 | 0 | 3 |
| FKTN | SMYD5 | 0.724776 | 3 | 0 | 3 |
| FKTN | NFAT5 | 0.722108 | 3 | 0 | 3 |
| FKTN | XPO6 | 0.716163 | 3 | 0 | 3 |
| FKTN | FAM120B | 0.705234 | 3 | 0 | 3 |
| FKTN | SASS6 | 0.704459 | 4 | 0 | 4 |
| FKTN | DCTD | 0.704177 | 3 | 0 | 3 |
| FKTN | ARPC5 | 0.703816 | 3 | 0 | 3 |
| FKTN | TRMT112 | 0.703417 | 3 | 0 | 3 |
For details and further investigation, click here
