| Full name: transcription elongation factor A1 | Alias Symbol: SII|TF2S|TFIIS | ||
| Type: protein-coding gene | Cytoband: 8q11.23 | ||
| Entrez ID: 6917 | HGNC ID: HGNC:11612 | Ensembl Gene: ENSG00000187735 | OMIM ID: 601425 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TCEA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TCEA1 | 6917 | 216241_s_at | 0.3208 | 0.4419 | |
| GSE20347 | TCEA1 | 6917 | 216241_s_at | 0.6561 | 0.0000 | |
| GSE23400 | TCEA1 | 6917 | 216241_s_at | 0.5517 | 0.0000 | |
| GSE26886 | TCEA1 | 6917 | 216241_s_at | 0.3817 | 0.0331 | |
| GSE29001 | TCEA1 | 6917 | 216241_s_at | 0.3139 | 0.4602 | |
| GSE38129 | TCEA1 | 6917 | 216241_s_at | 0.4806 | 0.0000 | |
| GSE45670 | TCEA1 | 6917 | 216241_s_at | 0.1844 | 0.2707 | |
| GSE53622 | TCEA1 | 6917 | 35348 | 0.6209 | 0.0000 | |
| GSE53624 | TCEA1 | 6917 | 35348 | 0.4978 | 0.0000 | |
| GSE63941 | TCEA1 | 6917 | 216241_s_at | 0.1277 | 0.8296 | |
| GSE77861 | TCEA1 | 6917 | 216241_s_at | 0.6236 | 0.0242 | |
| GSE97050 | TCEA1 | 6917 | A_23_P132444 | 0.1297 | 0.5580 | |
| SRP007169 | TCEA1 | 6917 | RNAseq | 0.0636 | 0.8788 | |
| SRP008496 | TCEA1 | 6917 | RNAseq | 0.1008 | 0.6538 | |
| SRP064894 | TCEA1 | 6917 | RNAseq | 0.2944 | 0.1160 | |
| SRP133303 | TCEA1 | 6917 | RNAseq | 0.3876 | 0.0003 | |
| SRP159526 | TCEA1 | 6917 | RNAseq | 0.2553 | 0.2358 | |
| SRP193095 | TCEA1 | 6917 | RNAseq | 0.1772 | 0.1255 | |
| SRP219564 | TCEA1 | 6917 | RNAseq | -0.0287 | 0.8696 | |
| TCGA | TCEA1 | 6917 | RNAseq | 0.1266 | 0.0126 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TCEA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TCEA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TCEA1 | 6917 | 14 | 2 | 14 | |
| GSE20123 | TCEA1 | 6917 | 14 | 2 | 14 | |
| GSE43470 | TCEA1 | 6917 | 13 | 3 | 27 | |
| GSE46452 | TCEA1 | 6917 | 20 | 3 | 36 | |
| GSE47630 | TCEA1 | 6917 | 23 | 1 | 16 | |
| GSE54993 | TCEA1 | 6917 | 1 | 16 | 53 | |
| GSE54994 | TCEA1 | 6917 | 28 | 0 | 25 | |
| GSE60625 | TCEA1 | 6917 | 0 | 4 | 7 | |
| GSE74703 | TCEA1 | 6917 | 12 | 2 | 22 | |
| GSE74704 | TCEA1 | 6917 | 10 | 0 | 10 | |
| TCGA | TCEA1 | 6917 | 43 | 10 | 43 |
Total number of gains: 178; Total number of losses: 43; Total Number of normals: 267.
Somatic mutations of TCEA1:
Generating mutation plots.
Highly correlated genes for TCEA1:
Showing top 20/1539 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TCEA1 | CCDC127 | 0.824503 | 3 | 0 | 3 |
| TCEA1 | KLHDC2 | 0.786715 | 3 | 0 | 3 |
| TCEA1 | ZNRF3 | 0.767873 | 3 | 0 | 3 |
| TCEA1 | MRPL48 | 0.767706 | 3 | 0 | 3 |
| TCEA1 | RAB34 | 0.752618 | 3 | 0 | 3 |
| TCEA1 | ZNF251 | 0.742811 | 4 | 0 | 4 |
| TCEA1 | CEP70 | 0.740377 | 3 | 0 | 3 |
| TCEA1 | CDC40 | 0.738035 | 3 | 0 | 3 |
| TCEA1 | FADS1 | 0.736183 | 3 | 0 | 3 |
| TCEA1 | ENY2 | 0.729406 | 11 | 0 | 9 |
| TCEA1 | CD164 | 0.727513 | 4 | 0 | 3 |
| TCEA1 | CMTM4 | 0.727359 | 3 | 0 | 3 |
| TCEA1 | NR3C1 | 0.724848 | 3 | 0 | 3 |
| TCEA1 | RAD21 | 0.724825 | 10 | 0 | 9 |
| TCEA1 | ANAPC4 | 0.722955 | 3 | 0 | 3 |
| TCEA1 | TMEM64 | 0.720128 | 4 | 0 | 4 |
| TCEA1 | RPS21 | 0.718212 | 3 | 0 | 3 |
| TCEA1 | HDDC2 | 0.713493 | 3 | 0 | 3 |
| TCEA1 | PYCR2 | 0.70996 | 3 | 0 | 3 |
| TCEA1 | NF1 | 0.708074 | 3 | 0 | 3 |
For details and further investigation, click here
