| Full name: SEL1L family member 3 | Alias Symbol: KIAA0746 | ||
| Type: protein-coding gene | Cytoband: 4p15.2 | ||
| Entrez ID: 23231 | HGNC ID: HGNC:29108 | Ensembl Gene: ENSG00000091490 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SEL1L3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEL1L3 | 23231 | 212314_at | 0.9226 | 0.4345 | |
| GSE20347 | SEL1L3 | 23231 | 212314_at | 1.5027 | 0.0000 | |
| GSE23400 | SEL1L3 | 23231 | 212314_at | 0.7046 | 0.0000 | |
| GSE26886 | SEL1L3 | 23231 | 212314_at | 1.9929 | 0.0000 | |
| GSE29001 | SEL1L3 | 23231 | 212314_at | 1.2126 | 0.0002 | |
| GSE38129 | SEL1L3 | 23231 | 212314_at | 1.4107 | 0.0000 | |
| GSE45670 | SEL1L3 | 23231 | 212314_at | 0.5067 | 0.2235 | |
| GSE53622 | SEL1L3 | 23231 | 122679 | 0.4651 | 0.0033 | |
| GSE53624 | SEL1L3 | 23231 | 122679 | 0.4990 | 0.0001 | |
| GSE63941 | SEL1L3 | 23231 | 212314_at | -1.7802 | 0.0198 | |
| GSE77861 | SEL1L3 | 23231 | 212311_at | 1.6921 | 0.0016 | |
| GSE97050 | SEL1L3 | 23231 | A_23_P426021 | 0.6435 | 0.2389 | |
| SRP007169 | SEL1L3 | 23231 | RNAseq | 3.3434 | 0.0000 | |
| SRP008496 | SEL1L3 | 23231 | RNAseq | 3.2248 | 0.0000 | |
| SRP064894 | SEL1L3 | 23231 | RNAseq | 0.3609 | 0.2783 | |
| SRP133303 | SEL1L3 | 23231 | RNAseq | 0.2612 | 0.3625 | |
| SRP159526 | SEL1L3 | 23231 | RNAseq | 0.7885 | 0.2159 | |
| SRP193095 | SEL1L3 | 23231 | RNAseq | -0.1911 | 0.6672 | |
| SRP219564 | SEL1L3 | 23231 | RNAseq | 1.5854 | 0.0000 | |
| TCGA | SEL1L3 | 23231 | RNAseq | -0.3232 | 0.0017 |
Upregulated datasets: 8; Downregulated datasets: 1.
Survival by SEL1L3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEL1L3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEL1L3 | 23231 | 0 | 18 | 12 | |
| GSE20123 | SEL1L3 | 23231 | 0 | 16 | 14 | |
| GSE43470 | SEL1L3 | 23231 | 0 | 15 | 28 | |
| GSE46452 | SEL1L3 | 23231 | 1 | 36 | 22 | |
| GSE47630 | SEL1L3 | 23231 | 1 | 19 | 20 | |
| GSE54993 | SEL1L3 | 23231 | 10 | 0 | 60 | |
| GSE54994 | SEL1L3 | 23231 | 6 | 12 | 35 | |
| GSE60625 | SEL1L3 | 23231 | 0 | 0 | 11 | |
| GSE74703 | SEL1L3 | 23231 | 0 | 13 | 23 | |
| GSE74704 | SEL1L3 | 23231 | 0 | 10 | 10 | |
| TCGA | SEL1L3 | 23231 | 11 | 48 | 37 |
Total number of gains: 29; Total number of losses: 187; Total Number of normals: 272.
Somatic mutations of SEL1L3:
Generating mutation plots.
Highly correlated genes for SEL1L3:
Showing top 20/1248 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEL1L3 | PPP1R35 | 0.853472 | 3 | 0 | 3 |
| SEL1L3 | NEK3 | 0.837087 | 3 | 0 | 3 |
| SEL1L3 | IDS | 0.794347 | 3 | 0 | 3 |
| SEL1L3 | THEM4 | 0.793094 | 3 | 0 | 3 |
| SEL1L3 | SMCR8 | 0.774624 | 3 | 0 | 3 |
| SEL1L3 | CENPV | 0.773644 | 4 | 0 | 4 |
| SEL1L3 | TNFAIP1 | 0.773416 | 3 | 0 | 3 |
| SEL1L3 | KREMEN1 | 0.771475 | 3 | 0 | 3 |
| SEL1L3 | LTBR | 0.769372 | 3 | 0 | 3 |
| SEL1L3 | LOXL1-AS1 | 0.766579 | 3 | 0 | 3 |
| SEL1L3 | PET117 | 0.759995 | 3 | 0 | 3 |
| SEL1L3 | NUDT15 | 0.756689 | 3 | 0 | 3 |
| SEL1L3 | PLEKHA3 | 0.754032 | 3 | 0 | 3 |
| SEL1L3 | POLRMT | 0.753317 | 3 | 0 | 3 |
| SEL1L3 | TRMT6 | 0.75321 | 3 | 0 | 3 |
| SEL1L3 | MSTO1 | 0.752897 | 3 | 0 | 3 |
| SEL1L3 | POU2AF1 | 0.750377 | 3 | 0 | 3 |
| SEL1L3 | BIRC6 | 0.74745 | 3 | 0 | 3 |
| SEL1L3 | MCM8 | 0.744892 | 3 | 0 | 3 |
| SEL1L3 | VMA21 | 0.742986 | 4 | 0 | 4 |
For details and further investigation, click here
