| Full name: HEAT repeat containing 3 | Alias Symbol: FLJ20718 | ||
| Type: protein-coding gene | Cytoband: 16q12.1 | ||
| Entrez ID: 55027 | HGNC ID: HGNC:26087 | Ensembl Gene: ENSG00000155393 | OMIM ID: 614951 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of HEATR3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HEATR3 | 55027 | 219289_at | 0.5448 | 0.2021 | |
| GSE20347 | HEATR3 | 55027 | 219289_at | 0.1710 | 0.3453 | |
| GSE23400 | HEATR3 | 55027 | 219289_at | 0.2128 | 0.0002 | |
| GSE26886 | HEATR3 | 55027 | 219289_at | -0.2842 | 0.2868 | |
| GSE29001 | HEATR3 | 55027 | 219289_at | 0.0535 | 0.8919 | |
| GSE38129 | HEATR3 | 55027 | 219289_at | 0.3096 | 0.0230 | |
| GSE45670 | HEATR3 | 55027 | 219289_at | 0.3301 | 0.0027 | |
| GSE53622 | HEATR3 | 55027 | 100701 | -0.0798 | 0.3230 | |
| GSE53624 | HEATR3 | 55027 | 100701 | 0.2127 | 0.0003 | |
| GSE63941 | HEATR3 | 55027 | 219289_at | 0.2341 | 0.4991 | |
| GSE77861 | HEATR3 | 55027 | 219289_at | 0.1447 | 0.5360 | |
| GSE97050 | HEATR3 | 55027 | A_24_P138713 | 0.0935 | 0.7206 | |
| SRP007169 | HEATR3 | 55027 | RNAseq | 0.2044 | 0.5684 | |
| SRP008496 | HEATR3 | 55027 | RNAseq | 0.1004 | 0.7156 | |
| SRP064894 | HEATR3 | 55027 | RNAseq | 0.2401 | 0.1046 | |
| SRP133303 | HEATR3 | 55027 | RNAseq | 0.4536 | 0.0001 | |
| SRP159526 | HEATR3 | 55027 | RNAseq | 0.1262 | 0.5391 | |
| SRP193095 | HEATR3 | 55027 | RNAseq | -0.0481 | 0.5162 | |
| SRP219564 | HEATR3 | 55027 | RNAseq | 0.1005 | 0.7249 | |
| TCGA | HEATR3 | 55027 | RNAseq | 0.0456 | 0.4387 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HEATR3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HEATR3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HEATR3 | 55027 | 4 | 1 | 25 | |
| GSE20123 | HEATR3 | 55027 | 3 | 1 | 26 | |
| GSE43470 | HEATR3 | 55027 | 2 | 7 | 34 | |
| GSE46452 | HEATR3 | 55027 | 38 | 1 | 20 | |
| GSE47630 | HEATR3 | 55027 | 11 | 7 | 22 | |
| GSE54993 | HEATR3 | 55027 | 2 | 5 | 63 | |
| GSE54994 | HEATR3 | 55027 | 6 | 10 | 37 | |
| GSE60625 | HEATR3 | 55027 | 4 | 0 | 7 | |
| GSE74703 | HEATR3 | 55027 | 2 | 4 | 30 | |
| GSE74704 | HEATR3 | 55027 | 3 | 1 | 16 | |
| TCGA | HEATR3 | 55027 | 25 | 12 | 59 |
Total number of gains: 100; Total number of losses: 49; Total Number of normals: 339.
Somatic mutations of HEATR3:
Generating mutation plots.
Highly correlated genes for HEATR3:
Showing top 20/511 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HEATR3 | GK5 | 0.730741 | 3 | 0 | 3 |
| HEATR3 | SLC35A3 | 0.710873 | 3 | 0 | 3 |
| HEATR3 | RBM27 | 0.6882 | 3 | 0 | 3 |
| HEATR3 | FNBP1L | 0.686268 | 3 | 0 | 3 |
| HEATR3 | SLC39A11 | 0.684244 | 3 | 0 | 3 |
| HEATR3 | IFNGR2 | 0.680312 | 3 | 0 | 3 |
| HEATR3 | SLC25A39 | 0.678118 | 3 | 0 | 3 |
| HEATR3 | ZNF276 | 0.673351 | 3 | 0 | 3 |
| HEATR3 | JKAMP | 0.672998 | 3 | 0 | 3 |
| HEATR3 | RASA2 | 0.672779 | 4 | 0 | 3 |
| HEATR3 | PTPN4 | 0.666351 | 3 | 0 | 3 |
| HEATR3 | ZNF274 | 0.661993 | 3 | 0 | 3 |
| HEATR3 | STAG1 | 0.661383 | 3 | 0 | 3 |
| HEATR3 | FBXW2 | 0.65611 | 3 | 0 | 3 |
| HEATR3 | TAF2 | 0.653764 | 4 | 0 | 3 |
| HEATR3 | CPNE8 | 0.653304 | 3 | 0 | 3 |
| HEATR3 | ELF4 | 0.643457 | 4 | 0 | 4 |
| HEATR3 | SLC30A5 | 0.642856 | 5 | 0 | 4 |
| HEATR3 | FARSA | 0.642286 | 5 | 0 | 5 |
| HEATR3 | SRBD1 | 0.635929 | 4 | 0 | 4 |
For details and further investigation, click here
