| Full name: interferon gamma receptor 2 | Alias Symbol: AF-1 | ||
| Type: protein-coding gene | Cytoband: 21q22.11 | ||
| Entrez ID: 3460 | HGNC ID: HGNC:5440 | Ensembl Gene: ENSG00000159128 | OMIM ID: 147569 |
| Drug and gene relationship at DGIdb | |||
IFNGR2 involved pathways:
Expression of IFNGR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFNGR2 | 3460 | 201642_at | 0.3810 | 0.2736 | |
| GSE20347 | IFNGR2 | 3460 | 201642_at | -0.4625 | 0.0010 | |
| GSE23400 | IFNGR2 | 3460 | 201642_at | -0.0088 | 0.9009 | |
| GSE26886 | IFNGR2 | 3460 | 201642_at | -0.4401 | 0.0114 | |
| GSE29001 | IFNGR2 | 3460 | 201642_at | -0.0725 | 0.7714 | |
| GSE38129 | IFNGR2 | 3460 | 201642_at | -0.1088 | 0.4654 | |
| GSE45670 | IFNGR2 | 3460 | 201642_at | -0.0687 | 0.6897 | |
| GSE53622 | IFNGR2 | 3460 | 87885 | -0.2198 | 0.0131 | |
| GSE53624 | IFNGR2 | 3460 | 87885 | -0.2650 | 0.0001 | |
| GSE63941 | IFNGR2 | 3460 | 201642_at | -0.0781 | 0.8838 | |
| GSE77861 | IFNGR2 | 3460 | 201642_at | -0.2060 | 0.3047 | |
| GSE97050 | IFNGR2 | 3460 | A_23_P29036 | -0.0239 | 0.9410 | |
| SRP007169 | IFNGR2 | 3460 | RNAseq | -0.9012 | 0.0195 | |
| SRP008496 | IFNGR2 | 3460 | RNAseq | -0.8240 | 0.0030 | |
| SRP064894 | IFNGR2 | 3460 | RNAseq | 0.0578 | 0.7310 | |
| SRP133303 | IFNGR2 | 3460 | RNAseq | -0.2609 | 0.0928 | |
| SRP159526 | IFNGR2 | 3460 | RNAseq | -0.3797 | 0.1976 | |
| SRP193095 | IFNGR2 | 3460 | RNAseq | -0.4100 | 0.0013 | |
| SRP219564 | IFNGR2 | 3460 | RNAseq | -0.5303 | 0.1120 | |
| TCGA | IFNGR2 | 3460 | RNAseq | 0.1928 | 0.0007 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IFNGR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFNGR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFNGR2 | 3460 | 2 | 8 | 20 | |
| GSE20123 | IFNGR2 | 3460 | 2 | 9 | 19 | |
| GSE43470 | IFNGR2 | 3460 | 3 | 9 | 31 | |
| GSE46452 | IFNGR2 | 3460 | 1 | 21 | 37 | |
| GSE47630 | IFNGR2 | 3460 | 6 | 17 | 17 | |
| GSE54993 | IFNGR2 | 3460 | 9 | 1 | 60 | |
| GSE54994 | IFNGR2 | 3460 | 1 | 9 | 43 | |
| GSE60625 | IFNGR2 | 3460 | 0 | 0 | 11 | |
| GSE74703 | IFNGR2 | 3460 | 3 | 6 | 27 | |
| GSE74704 | IFNGR2 | 3460 | 1 | 4 | 15 | |
| TCGA | IFNGR2 | 3460 | 9 | 35 | 52 |
Total number of gains: 37; Total number of losses: 119; Total Number of normals: 332.
Somatic mutations of IFNGR2:
Generating mutation plots.
Highly correlated genes for IFNGR2:
Showing top 20/204 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFNGR2 | TMEM86B | 0.756765 | 3 | 0 | 3 |
| IFNGR2 | PLXNB2 | 0.753587 | 3 | 0 | 3 |
| IFNGR2 | PCNT | 0.739636 | 3 | 0 | 3 |
| IFNGR2 | TRIM21 | 0.734897 | 3 | 0 | 3 |
| IFNGR2 | CCNK | 0.734657 | 3 | 0 | 3 |
| IFNGR2 | TCF19 | 0.731373 | 3 | 0 | 3 |
| IFNGR2 | ZBED4 | 0.725152 | 3 | 0 | 3 |
| IFNGR2 | SFMBT1 | 0.707571 | 3 | 0 | 3 |
| IFNGR2 | PWWP2A | 0.706743 | 3 | 0 | 3 |
| IFNGR2 | SMPD1 | 0.706476 | 3 | 0 | 3 |
| IFNGR2 | OLFM2 | 0.702246 | 3 | 0 | 3 |
| IFNGR2 | COMMD10 | 0.696012 | 3 | 0 | 3 |
| IFNGR2 | PUSL1 | 0.692224 | 3 | 0 | 3 |
| IFNGR2 | HEATR3 | 0.680312 | 3 | 0 | 3 |
| IFNGR2 | SLC25A40 | 0.675873 | 3 | 0 | 3 |
| IFNGR2 | COX19 | 0.661832 | 3 | 0 | 3 |
| IFNGR2 | MTA3 | 0.659821 | 4 | 0 | 3 |
| IFNGR2 | PNPO | 0.658625 | 3 | 0 | 3 |
| IFNGR2 | QSER1 | 0.652621 | 4 | 0 | 3 |
| IFNGR2 | SYNJ1 | 0.648721 | 4 | 0 | 3 |
For details and further investigation, click here
