TAF2

 

Full name: TATA-box binding protein associated factor 2 Alias Symbol: TAFII150|CIF150
Type: protein-coding gene Cytoband: 8q24.12
Entrez ID: 6873 HGNC ID: HGNC:11536 Ensembl Gene: ENSG00000064313 OMIM ID: 604912
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of TAF2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TAF2 6873 209523_at 0.7669 0.0950
GSE20347 TAF2 6873 209523_at 0.7899 0.0000
GSE23400 TAF2 6873 209523_at 0.8373 0.0000
GSE26886 TAF2 6873 209523_at 0.9868 0.0000
GSE29001 TAF2 6873 209523_at 0.5552 0.0138
GSE38129 TAF2 6873 209523_at 0.7635 0.0000
GSE45670 TAF2 6873 209523_at 0.5777 0.0005
GSE53622 TAF2 6873 54277 0.9270 0.0000
GSE53624 TAF2 6873 54277 0.8166 0.0000
GSE63941 TAF2 6873 209523_at 0.3783 0.4444
GSE77861 TAF2 6873 209523_at 0.4382 0.0257
GSE97050 TAF2 6873 A_23_P43248 0.5725 0.1146
SRP007169 TAF2 6873 RNAseq 0.3006 0.3906
SRP008496 TAF2 6873 RNAseq 0.4375 0.0788
SRP064894 TAF2 6873 RNAseq 0.6448 0.0570
SRP133303 TAF2 6873 RNAseq 0.7264 0.0000
SRP159526 TAF2 6873 RNAseq 0.3911 0.1088
SRP193095 TAF2 6873 RNAseq 0.4880 0.0000
SRP219564 TAF2 6873 RNAseq 0.3368 0.3508
TCGA TAF2 6873 RNAseq 0.2014 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by TAF2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TAF2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TAF2 6873 19 1 10
GSE20123 TAF2 6873 20 1 9
GSE43470 TAF2 6873 23 0 20
GSE46452 TAF2 6873 27 0 32
GSE47630 TAF2 6873 24 0 16
GSE54993 TAF2 6873 0 20 50
GSE54994 TAF2 6873 38 0 15
GSE60625 TAF2 6873 0 4 7
GSE74703 TAF2 6873 19 0 17
GSE74704 TAF2 6873 13 1 6
TCGA TAF2 6873 67 2 27

Total number of gains: 250; Total number of losses: 29; Total Number of normals: 209.  

 

Somatic mutations of TAF2:

 

Generating mutation plots.

 

Highly correlated genes for TAF2:

 

Showing top 20/2160 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TAF2CMTM40.86735303
TAF2ZBED10.852524303
TAF2EXOC60.80836303
TAF2MTBP0.787846606
TAF2LAPTM4B0.77974412011
TAF2STK30.77658711010
TAF2NUF20.77246707
TAF2DHRSX0.771089303
TAF2MTERF30.769715909
TAF2RAD210.76805811010
TAF2WDR540.76642606
TAF2NEK30.7639303
TAF2TBC1D310.76098611011
TAF2FZD60.76096110010
TAF2DPY19L40.75960912011
TAF2RILPL10.758096303
TAF2SLC25A320.75739412011
TAF2FBXL40.756655606
TAF2PPP1R9B0.754055303
TAF2GNG100.752172303

For details and further investigation, click here