| Full name: solute carrier family 35 member A3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p21.2 | ||
| Entrez ID: 23443 | HGNC ID: HGNC:11023 | Ensembl Gene: ENSG00000117620 | OMIM ID: 605632 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC35A3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC35A3 | 23443 | 226894_at | -0.0256 | 0.9676 | |
| GSE20347 | SLC35A3 | 23443 | 206770_s_at | -0.6799 | 0.0001 | |
| GSE23400 | SLC35A3 | 23443 | 206770_s_at | -0.1260 | 0.0506 | |
| GSE26886 | SLC35A3 | 23443 | 206770_s_at | -1.2518 | 0.0015 | |
| GSE29001 | SLC35A3 | 23443 | 206770_s_at | -0.8628 | 0.1012 | |
| GSE38129 | SLC35A3 | 23443 | 206770_s_at | -0.3097 | 0.1852 | |
| GSE45670 | SLC35A3 | 23443 | 226894_at | -0.3444 | 0.0532 | |
| GSE53622 | SLC35A3 | 23443 | 76202 | -0.5540 | 0.0000 | |
| GSE53624 | SLC35A3 | 23443 | 76202 | -0.8004 | 0.0000 | |
| GSE63941 | SLC35A3 | 23443 | 206770_s_at | 0.3660 | 0.4296 | |
| GSE77861 | SLC35A3 | 23443 | 206770_s_at | -0.8345 | 0.0279 | |
| GSE97050 | SLC35A3 | 23443 | A_23_P34460 | -0.1852 | 0.5332 | |
| SRP007169 | SLC35A3 | 23443 | RNAseq | -0.9106 | 0.0658 | |
| SRP008496 | SLC35A3 | 23443 | RNAseq | -0.8340 | 0.0039 | |
| SRP064894 | SLC35A3 | 23443 | RNAseq | -0.8030 | 0.0036 | |
| SRP133303 | SLC35A3 | 23443 | RNAseq | -0.1780 | 0.2177 | |
| SRP159526 | SLC35A3 | 23443 | RNAseq | -0.5148 | 0.1622 | |
| SRP193095 | SLC35A3 | 23443 | RNAseq | -0.7261 | 0.0000 | |
| SRP219564 | SLC35A3 | 23443 | RNAseq | -0.5712 | 0.1163 | |
| TCGA | SLC35A3 | 23443 | RNAseq | -0.3096 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SLC35A3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC35A3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC35A3 | 23443 | 0 | 10 | 20 | |
| GSE20123 | SLC35A3 | 23443 | 0 | 10 | 20 | |
| GSE43470 | SLC35A3 | 23443 | 1 | 6 | 36 | |
| GSE46452 | SLC35A3 | 23443 | 1 | 1 | 57 | |
| GSE47630 | SLC35A3 | 23443 | 9 | 5 | 26 | |
| GSE54993 | SLC35A3 | 23443 | 0 | 1 | 69 | |
| GSE54994 | SLC35A3 | 23443 | 6 | 3 | 44 | |
| GSE60625 | SLC35A3 | 23443 | 0 | 0 | 11 | |
| GSE74703 | SLC35A3 | 23443 | 0 | 5 | 31 | |
| GSE74704 | SLC35A3 | 23443 | 0 | 6 | 14 | |
| TCGA | SLC35A3 | 23443 | 8 | 24 | 64 |
Total number of gains: 25; Total number of losses: 71; Total Number of normals: 392.
Somatic mutations of SLC35A3:
Generating mutation plots.
Highly correlated genes for SLC35A3:
Showing top 20/1125 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC35A3 | KDM3A | 0.759815 | 3 | 0 | 3 |
| SLC35A3 | NIPSNAP3A | 0.754306 | 6 | 0 | 6 |
| SLC35A3 | SNX17 | 0.752994 | 3 | 0 | 3 |
| SLC35A3 | C3orf38 | 0.752774 | 4 | 0 | 4 |
| SLC35A3 | ECD | 0.743551 | 4 | 0 | 4 |
| SLC35A3 | FBXL3 | 0.742425 | 4 | 0 | 3 |
| SLC35A3 | PPWD1 | 0.741375 | 4 | 0 | 4 |
| SLC35A3 | TRAPPC6B | 0.741155 | 3 | 0 | 3 |
| SLC35A3 | HEATR5B | 0.738957 | 3 | 0 | 3 |
| SLC35A3 | GTF2A1 | 0.716204 | 3 | 0 | 3 |
| SLC35A3 | BLOC1S2 | 0.714775 | 4 | 0 | 3 |
| SLC35A3 | RABIF | 0.713849 | 4 | 0 | 3 |
| SLC35A3 | ATP6V1B2 | 0.712465 | 3 | 0 | 3 |
| SLC35A3 | HEATR3 | 0.710873 | 3 | 0 | 3 |
| SLC35A3 | PPID | 0.709011 | 3 | 0 | 3 |
| SLC35A3 | OSBPL8 | 0.70526 | 4 | 0 | 3 |
| SLC35A3 | FAM98C | 0.702777 | 3 | 0 | 3 |
| SLC35A3 | SNX4 | 0.700901 | 3 | 0 | 3 |
| SLC35A3 | ZCCHC9 | 0.698861 | 4 | 0 | 3 |
| SLC35A3 | CTTNBP2NL | 0.698486 | 7 | 0 | 6 |
For details and further investigation, click here
