FARSA

 

Full name: phenylalanyl-tRNA synthetase subunit alpha Alias Symbol: CML33
Type: protein-coding gene Cytoband: 19p13.13
Entrez ID: 2193 HGNC ID: HGNC:3592 Ensembl Gene: ENSG00000179115 OMIM ID: 602918
Drug and gene relationship at DGIdb

 

Expression of FARSA:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FARSA 2193 216602_s_at 0.4410 0.4319
GSE20347 FARSA 2193 202159_at 0.3173 0.0131
GSE23400 FARSA 2193 202159_at 0.4568 0.0000
GSE26886 FARSA 2193 202159_at 0.3819 0.0101
GSE29001 FARSA 2193 202159_at 0.7660 0.0275
GSE38129 FARSA 2193 202159_at 0.5237 0.0000
GSE45670 FARSA 2193 202159_at 0.5581 0.0000
GSE53622 FARSA 2193 147735 0.3392 0.0001
GSE53624 FARSA 2193 147735 0.5055 0.0000
GSE63941 FARSA 2193 202159_at 0.4694 0.1577
GSE77861 FARSA 2193 216602_s_at 0.5502 0.0253
GSE97050 FARSA 2193 A_23_P78685 0.3358 0.4159
SRP007169 FARSA 2193 RNAseq 0.3584 0.3703
SRP008496 FARSA 2193 RNAseq 0.5467 0.0655
SRP064894 FARSA 2193 RNAseq 0.8881 0.0004
SRP133303 FARSA 2193 RNAseq 0.4423 0.0194
SRP159526 FARSA 2193 RNAseq 0.3396 0.0728
SRP193095 FARSA 2193 RNAseq 0.3510 0.0002
SRP219564 FARSA 2193 RNAseq 1.0285 0.0088
TCGA FARSA 2193 RNAseq 0.1743 0.0008

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by FARSA expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of FARSA:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FARSA 2193 4 2 24
GSE20123 FARSA 2193 3 1 26
GSE43470 FARSA 2193 2 6 35
GSE46452 FARSA 2193 47 1 11
GSE47630 FARSA 2193 4 7 29
GSE54993 FARSA 2193 16 3 51
GSE54994 FARSA 2193 8 13 32
GSE60625 FARSA 2193 9 0 2
GSE74703 FARSA 2193 2 4 30
GSE74704 FARSA 2193 0 1 19
TCGA FARSA 2193 17 12 67

Total number of gains: 112; Total number of losses: 50; Total Number of normals: 326.  

 

Somatic mutations of FARSA:

 

Generating mutation plots.

 

Highly correlated genes for FARSA:

 

Showing top 20/1681 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FARSAKTI120.800167303
FARSAEXOC60.784581303
FARSATMEM2050.749551404
FARSATMEM2160.734533404
FARSAVPS33A0.732894404
FARSAATRIP0.731854303
FARSATADA30.727865303
FARSACEP410.725982404
FARSAZNF7400.72545404
FARSAALG100.722989403
FARSAELOF10.715019807
FARSARAD180.712348403
FARSADDX39A0.710963909
FARSAAJUBA0.708636404
FARSANR2C2AP0.707848707
FARSANACC10.705536504
FARSADHX570.705355505
FARSAZNF3170.705037706
FARSACREB10.70499303
FARSAFGFR1OP0.701395404

For details and further investigation, click here