| Full name: HESX homeobox 1 | Alias Symbol: RPX|ANF | ||
| Type: protein-coding gene | Cytoband: 3p14.3 | ||
| Entrez ID: 8820 | HGNC ID: HGNC:4877 | Ensembl Gene: ENSG00000163666 | OMIM ID: 601802 |
| Drug and gene relationship at DGIdb | |||
Expression of HESX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HESX1 | 8820 | 211267_at | -0.0303 | 0.9070 | |
| GSE20347 | HESX1 | 8820 | 211267_at | 0.0908 | 0.2652 | |
| GSE23400 | HESX1 | 8820 | 211267_at | -0.0402 | 0.1762 | |
| GSE26886 | HESX1 | 8820 | 211267_at | 0.0404 | 0.7337 | |
| GSE29001 | HESX1 | 8820 | 211267_at | -0.1103 | 0.4406 | |
| GSE38129 | HESX1 | 8820 | 211267_at | -0.0624 | 0.4105 | |
| GSE45670 | HESX1 | 8820 | 211267_at | -0.0389 | 0.7372 | |
| GSE53622 | HESX1 | 8820 | 75885 | -0.1326 | 0.3836 | |
| GSE53624 | HESX1 | 8820 | 75885 | -0.0953 | 0.4386 | |
| GSE63941 | HESX1 | 8820 | 211267_at | 0.1396 | 0.5887 | |
| GSE77861 | HESX1 | 8820 | 211267_at | -0.0758 | 0.4078 | |
| TCGA | HESX1 | 8820 | RNAseq | -0.5758 | 0.0577 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HESX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HESX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HESX1 | 8820 | 0 | 17 | 13 | |
| GSE20123 | HESX1 | 8820 | 0 | 18 | 12 | |
| GSE43470 | HESX1 | 8820 | 0 | 17 | 26 | |
| GSE46452 | HESX1 | 8820 | 2 | 17 | 40 | |
| GSE47630 | HESX1 | 8820 | 1 | 24 | 15 | |
| GSE54993 | HESX1 | 8820 | 6 | 2 | 62 | |
| GSE54994 | HESX1 | 8820 | 0 | 32 | 21 | |
| GSE60625 | HESX1 | 8820 | 5 | 0 | 6 | |
| GSE74703 | HESX1 | 8820 | 0 | 14 | 22 | |
| GSE74704 | HESX1 | 8820 | 0 | 11 | 9 | |
| TCGA | HESX1 | 8820 | 0 | 79 | 17 |
Total number of gains: 14; Total number of losses: 231; Total Number of normals: 243.
Somatic mutations of HESX1:
Generating mutation plots.
Highly correlated genes for HESX1:
Showing top 20/92 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HESX1 | OR3A2 | 0.691813 | 3 | 0 | 3 |
| HESX1 | ZNF460 | 0.654256 | 5 | 0 | 5 |
| HESX1 | OR1G1 | 0.630351 | 3 | 0 | 3 |
| HESX1 | MTAP | 0.614052 | 4 | 0 | 3 |
| HESX1 | KCNK13 | 0.607313 | 4 | 0 | 3 |
| HESX1 | CGA | 0.597946 | 4 | 0 | 3 |
| HESX1 | IL12B | 0.5974 | 4 | 0 | 3 |
| HESX1 | NTNG1 | 0.590197 | 4 | 0 | 4 |
| HESX1 | KCNAB3 | 0.585422 | 5 | 0 | 3 |
| HESX1 | HECW1 | 0.584877 | 5 | 0 | 4 |
| HESX1 | FOLH1 | 0.58374 | 5 | 0 | 4 |
| HESX1 | IRS4 | 0.582868 | 4 | 0 | 3 |
| HESX1 | NOL4 | 0.577069 | 3 | 0 | 3 |
| HESX1 | LUZP4 | 0.576805 | 4 | 0 | 3 |
| HESX1 | CCR9 | 0.576259 | 4 | 0 | 3 |
| HESX1 | KCNIP2 | 0.575107 | 6 | 0 | 5 |
| HESX1 | OR10C1 | 0.569484 | 5 | 0 | 4 |
| HESX1 | DCHS2 | 0.568625 | 4 | 0 | 3 |
| HESX1 | COLEC10 | 0.565269 | 5 | 0 | 4 |
| HESX1 | TLR8 | 0.56486 | 3 | 0 | 3 |
For details and further investigation, click here
