NOL4

 

Full name: nucleolar protein 4 Alias Symbol: NOLP|HRIHFB2255|CT125
Type: protein-coding gene Cytoband: 18q12.1
Entrez ID: 8715 HGNC ID: HGNC:7870 Ensembl Gene: ENSG00000101746 OMIM ID: 603577
Drug and gene relationship at DGIdb

 

Expression of NOL4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NOL4 8715 206045_s_at 0.5556 0.6103
GSE20347 NOL4 8715 206045_s_at -0.0118 0.8700
GSE23400 NOL4 8715 206045_s_at -0.0298 0.4575
GSE26886 NOL4 8715 206045_s_at 0.3251 0.3072
GSE29001 NOL4 8715 206045_s_at 0.0257 0.8815
GSE38129 NOL4 8715 206045_s_at 0.0214 0.9306
GSE45670 NOL4 8715 206045_s_at 0.1255 0.2185
GSE53622 NOL4 8715 7221 -0.3562 0.0050
GSE53624 NOL4 8715 7221 -0.2307 0.1023
GSE63941 NOL4 8715 206045_s_at -0.0049 0.9862
GSE77861 NOL4 8715 206045_s_at -0.0788 0.4508
TCGA NOL4 8715 RNAseq -1.4606 0.1799

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by NOL4 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of NOL4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NOL4 8715 2 5 23
GSE20123 NOL4 8715 2 6 22
GSE43470 NOL4 8715 0 3 40
GSE46452 NOL4 8715 1 25 33
GSE47630 NOL4 8715 5 20 15
GSE54993 NOL4 8715 7 1 62
GSE54994 NOL4 8715 1 16 36
GSE60625 NOL4 8715 0 4 7
GSE74703 NOL4 8715 0 3 33
GSE74704 NOL4 8715 1 5 14
TCGA NOL4 8715 15 35 46

Total number of gains: 34; Total number of losses: 123; Total Number of normals: 331.  


 

Somatic mutations of NOL4:

 

Generating mutation plots.

 

Highly correlated genes for NOL4:

 

Showing top 20/152 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NOL4GYPA0.774049303
NOL4MUC160.76637303
NOL4GLIS30.759278303
NOL4GRM60.753807303
NOL4TFF30.739278303
NOL4MBL20.717548303
NOL4SLC13A10.704502303
NOL4SCN2A0.703887303
NOL4CGA0.700758403
NOL4ST8SIA40.68592303
NOL4LRRC310.682581303
NOL4SLC17A30.679903404
NOL4RNF157-AS10.67964403
NOL4MMP260.670111403
NOL4CDX20.661613303
NOL4CCDC960.659562303
NOL4MAGEB20.657373403
NOL4GUCY1A20.657114303
NOL4IYD0.656942303
NOL4OSBPL70.653745303

For details and further investigation, click here