| Full name: potassium voltage-gated channel interacting protein 2 | Alias Symbol: KCHIP2 | ||
| Type: protein-coding gene | Cytoband: 10q24.32 | ||
| Entrez ID: 30819 | HGNC ID: HGNC:15522 | Ensembl Gene: ENSG00000120049 | OMIM ID: 604661 |
| Drug and gene relationship at DGIdb | |||
Expression of KCNIP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCNIP2 | 30819 | 223727_at | -0.0168 | 0.9646 | |
| GSE20347 | KCNIP2 | 30819 | 221321_s_at | 0.0291 | 0.7178 | |
| GSE23400 | KCNIP2 | 30819 | 221321_s_at | -0.0352 | 0.2050 | |
| GSE26886 | KCNIP2 | 30819 | 223727_at | -0.1180 | 0.3760 | |
| GSE29001 | KCNIP2 | 30819 | 221321_s_at | 0.0062 | 0.9761 | |
| GSE38129 | KCNIP2 | 30819 | 221321_s_at | -0.0354 | 0.6514 | |
| GSE45670 | KCNIP2 | 30819 | 223727_at | 0.1347 | 0.0739 | |
| GSE53622 | KCNIP2 | 30819 | 58754 | 0.1969 | 0.0748 | |
| GSE53624 | KCNIP2 | 30819 | 54161 | -0.1632 | 0.1127 | |
| GSE63941 | KCNIP2 | 30819 | 223727_at | 0.2813 | 0.0796 | |
| GSE77861 | KCNIP2 | 30819 | 223727_at | -0.0457 | 0.7152 | |
| GSE97050 | KCNIP2 | 30819 | A_24_P12998 | 0.2316 | 0.3640 | |
| SRP133303 | KCNIP2 | 30819 | RNAseq | -0.3819 | 0.0775 | |
| SRP159526 | KCNIP2 | 30819 | RNAseq | -0.1067 | 0.8182 | |
| SRP219564 | KCNIP2 | 30819 | RNAseq | -0.4547 | 0.3150 | |
| TCGA | KCNIP2 | 30819 | RNAseq | -0.3441 | 0.1010 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KCNIP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KCNIP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCNIP2 | 30819 | 2 | 9 | 19 | |
| GSE20123 | KCNIP2 | 30819 | 2 | 8 | 20 | |
| GSE43470 | KCNIP2 | 30819 | 0 | 8 | 35 | |
| GSE46452 | KCNIP2 | 30819 | 0 | 11 | 48 | |
| GSE47630 | KCNIP2 | 30819 | 2 | 14 | 24 | |
| GSE54993 | KCNIP2 | 30819 | 8 | 0 | 62 | |
| GSE54994 | KCNIP2 | 30819 | 1 | 12 | 40 | |
| GSE60625 | KCNIP2 | 30819 | 0 | 0 | 11 | |
| GSE74703 | KCNIP2 | 30819 | 0 | 5 | 31 | |
| GSE74704 | KCNIP2 | 30819 | 1 | 4 | 15 | |
| TCGA | KCNIP2 | 30819 | 5 | 29 | 62 |
Total number of gains: 21; Total number of losses: 100; Total Number of normals: 367.
Somatic mutations of KCNIP2:
Generating mutation plots.
Highly correlated genes for KCNIP2:
Showing top 20/452 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCNIP2 | SERPIND1 | 0.775074 | 3 | 0 | 3 |
| KCNIP2 | KRTAP5-AS1 | 0.682812 | 3 | 0 | 3 |
| KCNIP2 | TSSK6 | 0.677996 | 3 | 0 | 3 |
| KCNIP2 | CD79B | 0.671021 | 3 | 0 | 3 |
| KCNIP2 | INE1 | 0.670855 | 4 | 0 | 4 |
| KCNIP2 | CRYBA1 | 0.668382 | 4 | 0 | 3 |
| KCNIP2 | MTAP | 0.66771 | 4 | 0 | 4 |
| KCNIP2 | HCG9 | 0.660867 | 3 | 0 | 3 |
| KCNIP2 | SNCG | 0.655155 | 4 | 0 | 3 |
| KCNIP2 | DEFA6 | 0.653224 | 5 | 0 | 4 |
| KCNIP2 | NAT2 | 0.642977 | 4 | 0 | 4 |
| KCNIP2 | AKAP5 | 0.641628 | 3 | 0 | 3 |
| KCNIP2 | AMELY | 0.638849 | 4 | 0 | 3 |
| KCNIP2 | TMEM72-AS1 | 0.637688 | 4 | 0 | 4 |
| KCNIP2 | LIPF | 0.636822 | 5 | 0 | 5 |
| KCNIP2 | SLAMF6 | 0.631501 | 3 | 0 | 3 |
| KCNIP2 | OR10J1 | 0.630248 | 5 | 0 | 5 |
| KCNIP2 | GEMIN7 | 0.629385 | 5 | 0 | 4 |
| KCNIP2 | SLC2A4 | 0.626131 | 3 | 0 | 3 |
| KCNIP2 | MIR4755 | 0.623413 | 3 | 0 | 3 |
For details and further investigation, click here
