| Full name: hypoxia inducible factor 1 subunit alpha inhibitor | Alias Symbol: FLJ20615|DKFZp762F1811|FLJ22027|FIH1 | ||
| Type: protein-coding gene | Cytoband: 10q24.31 | ||
| Entrez ID: 55662 | HGNC ID: HGNC:17113 | Ensembl Gene: ENSG00000166135 | OMIM ID: 606615 |
| Drug and gene relationship at DGIdb | |||
Expression of HIF1AN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HIF1AN | 55662 | 226648_at | 0.5120 | 0.4558 | |
| GSE20347 | HIF1AN | 55662 | 59999_at | -0.0703 | 0.5725 | |
| GSE23400 | HIF1AN | 55662 | 218525_s_at | -0.0390 | 0.1861 | |
| GSE26886 | HIF1AN | 55662 | 59999_at | -0.2386 | 0.1856 | |
| GSE29001 | HIF1AN | 55662 | 59999_at | 0.1131 | 0.7792 | |
| GSE38129 | HIF1AN | 55662 | 59999_at | 0.0745 | 0.5243 | |
| GSE45670 | HIF1AN | 55662 | 226648_at | 0.0646 | 0.6154 | |
| GSE53622 | HIF1AN | 55662 | 75653 | -0.0977 | 0.1419 | |
| GSE53624 | HIF1AN | 55662 | 75653 | 0.1103 | 0.0416 | |
| GSE63941 | HIF1AN | 55662 | 226648_at | -0.0092 | 0.9768 | |
| GSE77861 | HIF1AN | 55662 | 218525_s_at | -0.0983 | 0.4723 | |
| GSE97050 | HIF1AN | 55662 | A_23_P46964 | 0.1117 | 0.7192 | |
| SRP007169 | HIF1AN | 55662 | RNAseq | -0.3394 | 0.3252 | |
| SRP008496 | HIF1AN | 55662 | RNAseq | -0.4339 | 0.0309 | |
| SRP064894 | HIF1AN | 55662 | RNAseq | -0.1308 | 0.2476 | |
| SRP133303 | HIF1AN | 55662 | RNAseq | -0.1247 | 0.3393 | |
| SRP159526 | HIF1AN | 55662 | RNAseq | -0.1878 | 0.4998 | |
| SRP193095 | HIF1AN | 55662 | RNAseq | 0.0035 | 0.9714 | |
| SRP219564 | HIF1AN | 55662 | RNAseq | -0.1304 | 0.5443 | |
| TCGA | HIF1AN | 55662 | RNAseq | -0.1683 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HIF1AN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HIF1AN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HIF1AN | 55662 | 1 | 8 | 21 | |
| GSE20123 | HIF1AN | 55662 | 1 | 7 | 22 | |
| GSE43470 | HIF1AN | 55662 | 0 | 8 | 35 | |
| GSE46452 | HIF1AN | 55662 | 0 | 11 | 48 | |
| GSE47630 | HIF1AN | 55662 | 2 | 14 | 24 | |
| GSE54993 | HIF1AN | 55662 | 8 | 0 | 62 | |
| GSE54994 | HIF1AN | 55662 | 1 | 12 | 40 | |
| GSE60625 | HIF1AN | 55662 | 0 | 0 | 11 | |
| GSE74703 | HIF1AN | 55662 | 0 | 5 | 31 | |
| GSE74704 | HIF1AN | 55662 | 0 | 4 | 16 | |
| TCGA | HIF1AN | 55662 | 5 | 28 | 63 |
Total number of gains: 18; Total number of losses: 97; Total Number of normals: 373.
Somatic mutations of HIF1AN:
Generating mutation plots.
Highly correlated genes for HIF1AN:
Showing top 20/74 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HIF1AN | DNAH9 | 0.678467 | 3 | 0 | 3 |
| HIF1AN | ENPP7 | 0.673625 | 3 | 0 | 3 |
| HIF1AN | NGB | 0.671272 | 3 | 0 | 3 |
| HIF1AN | SAMD14 | 0.665183 | 4 | 0 | 4 |
| HIF1AN | WDR83 | 0.661766 | 4 | 0 | 4 |
| HIF1AN | MPP2 | 0.650597 | 3 | 0 | 3 |
| HIF1AN | INPPL1 | 0.641065 | 3 | 0 | 3 |
| HIF1AN | EXOG | 0.638652 | 3 | 0 | 3 |
| HIF1AN | SFRP5 | 0.636867 | 3 | 0 | 3 |
| HIF1AN | SPTB | 0.624087 | 3 | 0 | 3 |
| HIF1AN | TRIM31 | 0.624023 | 4 | 0 | 4 |
| HIF1AN | CITED1 | 0.620393 | 3 | 0 | 3 |
| HIF1AN | CHMP1A | 0.618453 | 5 | 0 | 5 |
| HIF1AN | ZNF157 | 0.611189 | 4 | 0 | 4 |
| HIF1AN | MUC8 | 0.606402 | 3 | 0 | 3 |
| HIF1AN | RNF123 | 0.605686 | 4 | 0 | 3 |
| HIF1AN | NCAN | 0.604575 | 4 | 0 | 3 |
| HIF1AN | MAG | 0.604312 | 4 | 0 | 4 |
| HIF1AN | CYP3A4 | 0.601717 | 3 | 0 | 3 |
| HIF1AN | POLL | 0.600043 | 7 | 0 | 6 |
For details and further investigation, click here
