| Full name: charged multivesicular body protein 1A | Alias Symbol: KIAA0047|CHMP1|Vps46A | ||
| Type: protein-coding gene | Cytoband: 16q24.3 | ||
| Entrez ID: 5119 | HGNC ID: HGNC:8740 | Ensembl Gene: ENSG00000131165 | OMIM ID: 164010 |
| Drug and gene relationship at DGIdb | |||
Expression of CHMP1A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHMP1A | 5119 | 201933_at | 0.3038 | 0.2865 | |
| GSE20347 | CHMP1A | 5119 | 201933_at | 0.0772 | 0.4552 | |
| GSE23400 | CHMP1A | 5119 | 201933_at | 0.0243 | 0.7434 | |
| GSE26886 | CHMP1A | 5119 | 201933_at | -0.4851 | 0.0036 | |
| GSE29001 | CHMP1A | 5119 | 201933_at | -0.1474 | 0.6317 | |
| GSE38129 | CHMP1A | 5119 | 201933_at | 0.2520 | 0.0117 | |
| GSE45670 | CHMP1A | 5119 | 201933_at | 0.2400 | 0.0106 | |
| GSE53622 | CHMP1A | 5119 | 22829 | 0.0677 | 0.2836 | |
| GSE53624 | CHMP1A | 5119 | 22829 | -0.0729 | 0.3062 | |
| GSE63941 | CHMP1A | 5119 | 201933_at | 0.4089 | 0.3042 | |
| GSE77861 | CHMP1A | 5119 | 201933_at | 0.0521 | 0.7880 | |
| GSE97050 | CHMP1A | 5119 | A_24_P287780 | 0.0988 | 0.6672 | |
| SRP007169 | CHMP1A | 5119 | RNAseq | -1.3853 | 0.0000 | |
| SRP008496 | CHMP1A | 5119 | RNAseq | -1.2681 | 0.0000 | |
| SRP064894 | CHMP1A | 5119 | RNAseq | -0.1062 | 0.6319 | |
| SRP133303 | CHMP1A | 5119 | RNAseq | 0.3022 | 0.3274 | |
| SRP159526 | CHMP1A | 5119 | RNAseq | 0.0329 | 0.9329 | |
| SRP193095 | CHMP1A | 5119 | RNAseq | -0.2889 | 0.0114 | |
| SRP219564 | CHMP1A | 5119 | RNAseq | -0.3564 | 0.2416 | |
| TCGA | CHMP1A | 5119 | RNAseq | 0.0503 | 0.2953 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CHMP1A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHMP1A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHMP1A | 5119 | 4 | 3 | 23 | |
| GSE20123 | CHMP1A | 5119 | 4 | 3 | 23 | |
| GSE43470 | CHMP1A | 5119 | 1 | 13 | 29 | |
| GSE46452 | CHMP1A | 5119 | 38 | 1 | 20 | |
| GSE47630 | CHMP1A | 5119 | 11 | 9 | 20 | |
| GSE54993 | CHMP1A | 5119 | 3 | 4 | 63 | |
| GSE54994 | CHMP1A | 5119 | 9 | 11 | 33 | |
| GSE60625 | CHMP1A | 5119 | 4 | 0 | 7 | |
| GSE74703 | CHMP1A | 5119 | 1 | 9 | 26 | |
| GSE74704 | CHMP1A | 5119 | 3 | 1 | 16 | |
| TCGA | CHMP1A | 5119 | 26 | 15 | 55 |
Total number of gains: 104; Total number of losses: 69; Total Number of normals: 315.
Somatic mutations of CHMP1A:
Generating mutation plots.
Highly correlated genes for CHMP1A:
Showing top 20/346 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHMP1A | CORT | 0.764498 | 3 | 0 | 3 |
| CHMP1A | YY2 | 0.757871 | 3 | 0 | 3 |
| CHMP1A | PRSS38 | 0.749705 | 3 | 0 | 3 |
| CHMP1A | PROCA1 | 0.719681 | 3 | 0 | 3 |
| CHMP1A | OTOG | 0.718573 | 3 | 0 | 3 |
| CHMP1A | LBX2 | 0.71006 | 3 | 0 | 3 |
| CHMP1A | TTLL9 | 0.709792 | 4 | 0 | 4 |
| CHMP1A | KRTAP10-12 | 0.705387 | 3 | 0 | 3 |
| CHMP1A | SPRED3 | 0.704839 | 3 | 0 | 3 |
| CHMP1A | OR2T27 | 0.704765 | 3 | 0 | 3 |
| CHMP1A | SLC26A1 | 0.700945 | 3 | 0 | 3 |
| CHMP1A | OTOP2 | 0.698563 | 3 | 0 | 3 |
| CHMP1A | KCNH3 | 0.692315 | 3 | 0 | 3 |
| CHMP1A | COPS7B | 0.689527 | 4 | 0 | 4 |
| CHMP1A | MRGPRG | 0.686903 | 3 | 0 | 3 |
| CHMP1A | KLF17 | 0.686649 | 3 | 0 | 3 |
| CHMP1A | DUOXA2 | 0.686641 | 3 | 0 | 3 |
| CHMP1A | TTC7A | 0.682218 | 3 | 0 | 3 |
| CHMP1A | PLA2G2C | 0.681211 | 3 | 0 | 3 |
| CHMP1A | LHB | 0.676813 | 3 | 0 | 3 |
For details and further investigation, click here
