| Full name: ring finger protein 123 | Alias Symbol: FLJ12565|KPC1 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 63891 | HGNC ID: HGNC:21148 | Ensembl Gene: ENSG00000164068 | OMIM ID: 614472 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RNF123:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF123 | 63891 | 221063_x_at | 0.0481 | 0.8669 | |
| GSE20347 | RNF123 | 63891 | 221063_x_at | -0.4017 | 0.0000 | |
| GSE23400 | RNF123 | 63891 | 221063_x_at | -0.2316 | 0.0000 | |
| GSE26886 | RNF123 | 63891 | 221063_x_at | -0.8397 | 0.0000 | |
| GSE29001 | RNF123 | 63891 | 221063_x_at | -0.2887 | 0.2474 | |
| GSE38129 | RNF123 | 63891 | 221063_x_at | -0.4043 | 0.0000 | |
| GSE45670 | RNF123 | 63891 | 221063_x_at | 0.1816 | 0.0317 | |
| GSE53622 | RNF123 | 63891 | 19088 | -0.5540 | 0.0000 | |
| GSE53624 | RNF123 | 63891 | 19088 | -0.3410 | 0.0000 | |
| GSE63941 | RNF123 | 63891 | 221063_x_at | 0.9774 | 0.0018 | |
| GSE77861 | RNF123 | 63891 | 224186_s_at | -0.1466 | 0.5161 | |
| GSE97050 | RNF123 | 63891 | A_23_P250054 | 0.2017 | 0.5109 | |
| SRP007169 | RNF123 | 63891 | RNAseq | 0.0974 | 0.8549 | |
| SRP008496 | RNF123 | 63891 | RNAseq | -0.2002 | 0.5766 | |
| SRP064894 | RNF123 | 63891 | RNAseq | -0.0637 | 0.5872 | |
| SRP133303 | RNF123 | 63891 | RNAseq | -0.2128 | 0.1662 | |
| SRP159526 | RNF123 | 63891 | RNAseq | -0.2099 | 0.1863 | |
| SRP193095 | RNF123 | 63891 | RNAseq | -0.0654 | 0.6269 | |
| SRP219564 | RNF123 | 63891 | RNAseq | -0.3872 | 0.2778 | |
| TCGA | RNF123 | 63891 | RNAseq | -0.2299 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RNF123 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF123:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF123 | 63891 | 0 | 18 | 12 | |
| GSE20123 | RNF123 | 63891 | 0 | 19 | 11 | |
| GSE43470 | RNF123 | 63891 | 0 | 18 | 25 | |
| GSE46452 | RNF123 | 63891 | 2 | 16 | 41 | |
| GSE47630 | RNF123 | 63891 | 1 | 24 | 15 | |
| GSE54993 | RNF123 | 63891 | 6 | 2 | 62 | |
| GSE54994 | RNF123 | 63891 | 0 | 36 | 17 | |
| GSE60625 | RNF123 | 63891 | 5 | 0 | 6 | |
| GSE74703 | RNF123 | 63891 | 0 | 14 | 22 | |
| GSE74704 | RNF123 | 63891 | 0 | 12 | 8 | |
| TCGA | RNF123 | 63891 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 237; Total Number of normals: 237.
Somatic mutations of RNF123:
Generating mutation plots.
Highly correlated genes for RNF123:
Showing top 20/547 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF123 | PGC | 0.808942 | 4 | 0 | 4 |
| RNF123 | LY6H | 0.751874 | 3 | 0 | 3 |
| RNF123 | SP7 | 0.746745 | 3 | 0 | 3 |
| RNF123 | SLC22A31 | 0.746563 | 3 | 0 | 3 |
| RNF123 | MAT1A | 0.745099 | 4 | 0 | 3 |
| RNF123 | GABRB1 | 0.744611 | 3 | 0 | 3 |
| RNF123 | KLHL35 | 0.738754 | 4 | 0 | 3 |
| RNF123 | SLC18A3 | 0.731594 | 3 | 0 | 3 |
| RNF123 | PHOSPHO1 | 0.723733 | 3 | 0 | 3 |
| RNF123 | IZUMO2 | 0.718492 | 3 | 0 | 3 |
| RNF123 | BLK | 0.717613 | 3 | 0 | 3 |
| RNF123 | KCNA7 | 0.713754 | 3 | 0 | 3 |
| RNF123 | LRRC3 | 0.712972 | 3 | 0 | 3 |
| RNF123 | DNAL4 | 0.70987 | 3 | 0 | 3 |
| RNF123 | DOK7 | 0.709668 | 3 | 0 | 3 |
| RNF123 | B3GNT8 | 0.709397 | 3 | 0 | 3 |
| RNF123 | DPYSL4 | 0.707484 | 4 | 0 | 4 |
| RNF123 | DRG2 | 0.706585 | 3 | 0 | 3 |
| RNF123 | OR10H1 | 0.706037 | 3 | 0 | 3 |
| RNF123 | CEND1 | 0.706002 | 4 | 0 | 3 |
For details and further investigation, click here
