| Full name: neuroglobin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 58157 | HGNC ID: HGNC:14077 | Ensembl Gene: ENSG00000165553 | OMIM ID: 605304 |
| Drug and gene relationship at DGIdb | |||
Expression of NGB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NGB | 58157 | 236677_at | 0.1439 | 0.7642 | |
| GSE20347 | NGB | 58157 | 220337_at | -0.1345 | 0.1263 | |
| GSE23400 | NGB | 58157 | 220337_at | -0.1625 | 0.0001 | |
| GSE26886 | NGB | 58157 | 236677_at | 0.3283 | 0.2532 | |
| GSE29001 | NGB | 58157 | 220337_at | -0.0709 | 0.6737 | |
| GSE38129 | NGB | 58157 | 220337_at | -0.1696 | 0.0642 | |
| GSE45670 | NGB | 58157 | 236677_at | 0.2387 | 0.0529 | |
| GSE53622 | NGB | 58157 | 26865 | 0.3054 | 0.1814 | |
| GSE53624 | NGB | 58157 | 26865 | 0.4951 | 0.0008 | |
| GSE63941 | NGB | 58157 | 236677_at | -0.0008 | 0.9976 | |
| GSE77861 | NGB | 58157 | 220337_at | -0.1721 | 0.3888 | |
| GSE97050 | NGB | 58157 | A_23_P140375 | 0.7381 | 0.2168 | |
| TCGA | NGB | 58157 | RNAseq | 0.2586 | 0.7103 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NGB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NGB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NGB | 58157 | 8 | 3 | 19 | |
| GSE20123 | NGB | 58157 | 8 | 3 | 19 | |
| GSE43470 | NGB | 58157 | 8 | 3 | 32 | |
| GSE46452 | NGB | 58157 | 16 | 3 | 40 | |
| GSE47630 | NGB | 58157 | 11 | 8 | 21 | |
| GSE54993 | NGB | 58157 | 3 | 8 | 59 | |
| GSE54994 | NGB | 58157 | 19 | 4 | 30 | |
| GSE60625 | NGB | 58157 | 0 | 2 | 9 | |
| GSE74703 | NGB | 58157 | 7 | 3 | 26 | |
| GSE74704 | NGB | 58157 | 3 | 3 | 14 | |
| TCGA | NGB | 58157 | 32 | 16 | 48 |
Total number of gains: 115; Total number of losses: 56; Total Number of normals: 317.
Somatic mutations of NGB:
Generating mutation plots.
Highly correlated genes for NGB:
Showing top 20/675 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NGB | PHF7 | 0.730795 | 5 | 0 | 5 |
| NGB | CLDN9 | 0.725006 | 6 | 0 | 6 |
| NGB | FUT5 | 0.715109 | 5 | 0 | 5 |
| NGB | ADAMTS7 | 0.709334 | 5 | 0 | 5 |
| NGB | FOXS1 | 0.707877 | 3 | 0 | 3 |
| NGB | OPRL1 | 0.701865 | 5 | 0 | 5 |
| NGB | IL18BP | 0.697854 | 6 | 0 | 6 |
| NGB | SCNN1G | 0.695589 | 4 | 0 | 3 |
| NGB | RGSL1 | 0.695564 | 4 | 0 | 4 |
| NGB | ENTPD2 | 0.692599 | 6 | 0 | 6 |
| NGB | GABRR2 | 0.692468 | 5 | 0 | 5 |
| NGB | EPN1 | 0.6912 | 3 | 0 | 3 |
| NGB | CALCR | 0.68961 | 3 | 0 | 3 |
| NGB | COL8A2 | 0.689259 | 3 | 0 | 3 |
| NGB | HHLA1 | 0.687617 | 4 | 0 | 4 |
| NGB | ORM1 | 0.687558 | 3 | 0 | 3 |
| NGB | OR2H2 | 0.680166 | 4 | 0 | 4 |
| NGB | MASP2 | 0.678915 | 4 | 0 | 4 |
| NGB | CHRND | 0.677967 | 3 | 0 | 3 |
| NGB | SNX8 | 0.677236 | 3 | 0 | 3 |
For details and further investigation, click here
