| Full name: histone H4 transcription factor | Alias Symbol: DKFZP434F162|HiNF-P|ZNF743 | ||
| Type: protein-coding gene | Cytoband: 11q23.3 | ||
| Entrez ID: 25988 | HGNC ID: HGNC:17850 | Ensembl Gene: ENSG00000172273 | OMIM ID: 607099 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of HINFP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HINFP | 25988 | 206495_s_at | -0.0932 | 0.7831 | |
| GSE20347 | HINFP | 25988 | 206495_s_at | 0.0445 | 0.6681 | |
| GSE23400 | HINFP | 25988 | 206495_s_at | 0.0786 | 0.0342 | |
| GSE26886 | HINFP | 25988 | 206495_s_at | -0.0674 | 0.7568 | |
| GSE29001 | HINFP | 25988 | 206495_s_at | 0.0326 | 0.8717 | |
| GSE38129 | HINFP | 25988 | 206495_s_at | -0.0733 | 0.4139 | |
| GSE45670 | HINFP | 25988 | 206495_s_at | -0.0571 | 0.7058 | |
| GSE53622 | HINFP | 25988 | 1810 | 0.0185 | 0.7764 | |
| GSE53624 | HINFP | 25988 | 1810 | -0.0094 | 0.9059 | |
| GSE63941 | HINFP | 25988 | 206495_s_at | 0.1252 | 0.7318 | |
| GSE77861 | HINFP | 25988 | 206495_s_at | 0.0459 | 0.8219 | |
| GSE97050 | HINFP | 25988 | A_24_P121171 | -0.0853 | 0.7206 | |
| SRP007169 | HINFP | 25988 | RNAseq | -0.5933 | 0.1692 | |
| SRP008496 | HINFP | 25988 | RNAseq | -0.4854 | 0.1194 | |
| SRP064894 | HINFP | 25988 | RNAseq | 0.0148 | 0.9027 | |
| SRP133303 | HINFP | 25988 | RNAseq | -0.3132 | 0.0261 | |
| SRP159526 | HINFP | 25988 | RNAseq | -0.4083 | 0.1533 | |
| SRP193095 | HINFP | 25988 | RNAseq | -0.3685 | 0.0000 | |
| SRP219564 | HINFP | 25988 | RNAseq | -0.1613 | 0.7002 | |
| TCGA | HINFP | 25988 | RNAseq | -0.1003 | 0.1123 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HINFP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HINFP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HINFP | 25988 | 1 | 11 | 18 | |
| GSE20123 | HINFP | 25988 | 1 | 11 | 18 | |
| GSE43470 | HINFP | 25988 | 2 | 8 | 33 | |
| GSE46452 | HINFP | 25988 | 3 | 26 | 30 | |
| GSE47630 | HINFP | 25988 | 2 | 19 | 19 | |
| GSE54993 | HINFP | 25988 | 10 | 0 | 60 | |
| GSE54994 | HINFP | 25988 | 5 | 19 | 29 | |
| GSE60625 | HINFP | 25988 | 0 | 3 | 8 | |
| GSE74703 | HINFP | 25988 | 1 | 5 | 30 | |
| GSE74704 | HINFP | 25988 | 0 | 7 | 13 | |
| TCGA | HINFP | 25988 | 4 | 51 | 41 |
Total number of gains: 29; Total number of losses: 160; Total Number of normals: 299.
Somatic mutations of HINFP:
Generating mutation plots.
Highly correlated genes for HINFP:
Showing top 20/31 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HINFP | MECR | 0.742947 | 3 | 0 | 3 |
| HINFP | OPRD1 | 0.71349 | 3 | 0 | 3 |
| HINFP | IKBKB | 0.677515 | 3 | 0 | 3 |
| HINFP | HPS1 | 0.657902 | 4 | 0 | 3 |
| HINFP | ZFAT | 0.657267 | 3 | 0 | 3 |
| HINFP | NTHL1 | 0.647808 | 3 | 0 | 3 |
| HINFP | GNMT | 0.645059 | 4 | 0 | 3 |
| HINFP | UBXN2B | 0.640422 | 4 | 0 | 4 |
| HINFP | KLHL34 | 0.631682 | 4 | 0 | 3 |
| HINFP | ZNF682 | 0.61851 | 4 | 0 | 3 |
| HINFP | CCKBR | 0.617522 | 3 | 0 | 3 |
| HINFP | ARFGEF1 | 0.599196 | 4 | 0 | 3 |
| HINFP | NINJ2 | 0.594628 | 5 | 0 | 3 |
| HINFP | THAP3 | 0.593781 | 4 | 0 | 3 |
| HINFP | PGBD2 | 0.589521 | 4 | 0 | 3 |
| HINFP | TECPR1 | 0.584772 | 3 | 0 | 3 |
| HINFP | CUTC | 0.58238 | 4 | 0 | 3 |
| HINFP | PPOX | 0.568617 | 5 | 0 | 3 |
| HINFP | LARP4B | 0.568328 | 5 | 0 | 3 |
| HINFP | DISP1 | 0.566925 | 3 | 0 | 3 |
For details and further investigation, click here
