| Full name: THAP domain containing 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p36.31 | ||
| Entrez ID: 90326 | HGNC ID: HGNC:20855 | Ensembl Gene: ENSG00000041988 | OMIM ID: 612532 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of THAP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | THAP3 | 90326 | 213192_at | 0.1224 | 0.7160 | |
| GSE20347 | THAP3 | 90326 | 213192_at | 0.2540 | 0.0043 | |
| GSE23400 | THAP3 | 90326 | 213192_at | -0.0367 | 0.3481 | |
| GSE26886 | THAP3 | 90326 | 213192_at | 0.6920 | 0.0000 | |
| GSE29001 | THAP3 | 90326 | 213192_at | 0.0074 | 0.9665 | |
| GSE38129 | THAP3 | 90326 | 213192_at | 0.0767 | 0.3537 | |
| GSE45670 | THAP3 | 90326 | 213192_at | 0.0214 | 0.8611 | |
| GSE53622 | THAP3 | 90326 | 41140 | 0.3006 | 0.0000 | |
| GSE53624 | THAP3 | 90326 | 41140 | 0.2073 | 0.0018 | |
| GSE63941 | THAP3 | 90326 | 213192_at | -0.3176 | 0.2772 | |
| GSE77861 | THAP3 | 90326 | 213192_at | 0.1061 | 0.3385 | |
| GSE97050 | THAP3 | 90326 | A_23_P340890 | 0.0593 | 0.8375 | |
| SRP007169 | THAP3 | 90326 | RNAseq | -0.4992 | 0.3015 | |
| SRP008496 | THAP3 | 90326 | RNAseq | -0.1822 | 0.5859 | |
| SRP064894 | THAP3 | 90326 | RNAseq | 0.7918 | 0.0425 | |
| SRP133303 | THAP3 | 90326 | RNAseq | 0.1751 | 0.3466 | |
| SRP159526 | THAP3 | 90326 | RNAseq | 0.3843 | 0.2903 | |
| SRP193095 | THAP3 | 90326 | RNAseq | 0.2104 | 0.0954 | |
| SRP219564 | THAP3 | 90326 | RNAseq | 0.3723 | 0.3677 | |
| TCGA | THAP3 | 90326 | RNAseq | -0.0162 | 0.8463 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by THAP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of THAP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | THAP3 | 90326 | 3 | 6 | 21 | |
| GSE20123 | THAP3 | 90326 | 3 | 5 | 22 | |
| GSE43470 | THAP3 | 90326 | 6 | 5 | 32 | |
| GSE46452 | THAP3 | 90326 | 7 | 1 | 51 | |
| GSE47630 | THAP3 | 90326 | 8 | 4 | 28 | |
| GSE54993 | THAP3 | 90326 | 3 | 2 | 65 | |
| GSE54994 | THAP3 | 90326 | 14 | 3 | 36 | |
| GSE60625 | THAP3 | 90326 | 0 | 0 | 11 | |
| GSE74703 | THAP3 | 90326 | 5 | 3 | 28 | |
| GSE74704 | THAP3 | 90326 | 3 | 0 | 17 | |
| TCGA | THAP3 | 90326 | 12 | 22 | 62 |
Total number of gains: 64; Total number of losses: 51; Total Number of normals: 373.
Somatic mutations of THAP3:
Generating mutation plots.
Highly correlated genes for THAP3:
Showing top 20/369 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| THAP3 | RAB44 | 0.802098 | 3 | 0 | 3 |
| THAP3 | LRFN3 | 0.792463 | 3 | 0 | 3 |
| THAP3 | ASMTL | 0.786363 | 3 | 0 | 3 |
| THAP3 | C7orf26 | 0.772179 | 3 | 0 | 3 |
| THAP3 | C19orf25 | 0.747913 | 3 | 0 | 3 |
| THAP3 | B3GALT1 | 0.734276 | 3 | 0 | 3 |
| THAP3 | OR2T1 | 0.730039 | 3 | 0 | 3 |
| THAP3 | SHANK1 | 0.723318 | 3 | 0 | 3 |
| THAP3 | PRR7 | 0.722992 | 3 | 0 | 3 |
| THAP3 | AMPD2 | 0.71914 | 5 | 0 | 5 |
| THAP3 | ESPNL | 0.711897 | 3 | 0 | 3 |
| THAP3 | LMAN1L | 0.711157 | 3 | 0 | 3 |
| THAP3 | SLC5A5 | 0.710538 | 3 | 0 | 3 |
| THAP3 | TXNDC2 | 0.707437 | 3 | 0 | 3 |
| THAP3 | OR2D3 | 0.705298 | 3 | 0 | 3 |
| THAP3 | OR56A5 | 0.703418 | 3 | 0 | 3 |
| THAP3 | PNMA3 | 0.699937 | 5 | 0 | 5 |
| THAP3 | PTK2B | 0.693759 | 3 | 0 | 3 |
| THAP3 | WNT9A | 0.69143 | 4 | 0 | 3 |
| THAP3 | C19orf53 | 0.688733 | 4 | 0 | 4 |
For details and further investigation, click here
