LARP4B

 

Full name: La ribonucleoprotein domain family member 4B Alias Symbol: 
Type: protein-coding gene Cytoband: 10p15.3
Entrez ID: 23185 HGNC ID: HGNC:28987 Ensembl Gene: ENSG00000107929 OMIM ID: 616513
Drug and gene relationship at DGIdb

 

Expression of LARP4B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 LARP4B 23185 208953_at -0.0421 0.9511
GSE20347 LARP4B 23185 208953_at -0.4885 0.0060
GSE23400 LARP4B 23185 208952_s_at 0.0505 0.5174
GSE26886 LARP4B 23185 208954_s_at -0.9967 0.0001
GSE29001 LARP4B 23185 208954_s_at -0.2982 0.4904
GSE38129 LARP4B 23185 208953_at -0.1593 0.4655
GSE45670 LARP4B 23185 208953_at -0.2643 0.0951
GSE53622 LARP4B 23185 62320 -0.3919 0.0000
GSE53624 LARP4B 23185 55958 -0.2926 0.0000
GSE63941 LARP4B 23185 208953_at 0.4707 0.2017
GSE77861 LARP4B 23185 208953_at -0.2616 0.3444
GSE97050 LARP4B 23185 A_33_P3382730 0.1710 0.5830
SRP007169 LARP4B 23185 RNAseq -0.3649 0.3538
SRP008496 LARP4B 23185 RNAseq -0.2973 0.2359
SRP064894 LARP4B 23185 RNAseq -0.5315 0.0000
SRP133303 LARP4B 23185 RNAseq -0.2911 0.0379
SRP159526 LARP4B 23185 RNAseq -0.7520 0.0131
SRP193095 LARP4B 23185 RNAseq -0.4409 0.0000
SRP219564 LARP4B 23185 RNAseq -0.5169 0.1458
TCGA LARP4B 23185 RNAseq -0.0845 0.0883

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by LARP4B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of LARP4B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LARP4B 23185 5 10 15
GSE20123 LARP4B 23185 5 10 15
GSE43470 LARP4B 23185 3 8 32
GSE46452 LARP4B 23185 2 14 43
GSE47630 LARP4B 23185 5 15 20
GSE54993 LARP4B 23185 11 0 59
GSE54994 LARP4B 23185 4 10 39
GSE60625 LARP4B 23185 0 0 11
GSE74703 LARP4B 23185 2 5 29
GSE74704 LARP4B 23185 1 9 10
TCGA LARP4B 23185 17 27 52

Total number of gains: 55; Total number of losses: 108; Total Number of normals: 325.  

 

Somatic mutations of LARP4B:

 

Generating mutation plots.

 

Highly correlated genes for LARP4B:

 

Showing top 20/322 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LARP4BBUD130.786807303
LARP4BZDHHC200.75388303
LARP4BCCDC960.746456303
LARP4BSUDS30.728433303
LARP4BRASSF70.715792404
LARP4BHECTD10.712042505
LARP4BNT5C1A0.68012303
LARP4BOTUB20.677816404
LARP4BRHBDL20.676297404
LARP4BC6orf1320.660214505
LARP4BLIPH0.656465403
LARP4BTMPRSS20.65496403
LARP4BADAMTS170.654868404
LARP4BHMGCLL10.646501303
LARP4BMRPS160.646077504
LARP4BFBXO340.644705705
LARP4BUBXN60.644501303
LARP4BABLIM30.641747504
LARP4BB3GNT80.640243403
LARP4BBBOX10.637582605

For details and further investigation, click here