| Full name: major histocompatibility complex, class II, DR beta 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p21.3 alternate reference locus | ||
| Entrez ID: 3126 | HGNC ID: HGNC:4952 | Ensembl Gene: ENSG00000227357 | OMIM ID: |
| Related drugs: 1D09C3... [more] | |||
HLA-DRB4 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04612 | Antigen processing and presentation | |
| hsa05152 | Tuberculosis |
Expression of HLA-DRB4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HLA-DRB4 | 3126 | 209728_at | -0.4001 | 0.8567 | |
| GSE20347 | HLA-DRB4 | 3126 | 209728_at | -0.4123 | 0.3296 | |
| GSE23400 | HLA-DRB4 | 3126 | 209728_at | -0.2131 | 0.3112 | |
| GSE26886 | HLA-DRB4 | 3126 | 209728_at | -0.6013 | 0.4020 | |
| GSE29001 | HLA-DRB4 | 3126 | 209728_at | -0.1616 | 0.8837 | |
| GSE38129 | HLA-DRB4 | 3126 | 209728_at | -0.6158 | 0.2123 | |
| GSE45670 | HLA-DRB4 | 3126 | 209728_at | -0.4921 | 0.4783 | |
| GSE63941 | HLA-DRB4 | 3126 | 209728_at | 0.2827 | 0.6086 | |
| GSE97050 | HLA-DRB4 | 3126 | A_24_P370472 | 0.5365 | 0.4031 | |
| SRP007169 | HLA-DRB4 | 3126 | RNAseq | 1.2429 | 0.1378 | |
| SRP008496 | HLA-DRB4 | 3126 | RNAseq | 0.8615 | 0.3493 |
Upregulated datasets: 0; Downregulated datasets: 0.
Copy number change of HLA-DRB4:
No record found for this gene.
Somatic mutations of HLA-DRB4:
Generating mutation plots.
Highly correlated genes for HLA-DRB4:
Showing all 14 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HLA-DRB4 | FAM162B | 0.743294 | 3 | 0 | 3 |
| HLA-DRB4 | IRF8 | 0.682513 | 4 | 0 | 3 |
| HLA-DRB4 | HLA-DQB1 | 0.65634 | 6 | 0 | 4 |
| HLA-DRB4 | HLA-DMB | 0.643005 | 4 | 0 | 3 |
| HLA-DRB4 | KCNE3 | 0.629011 | 3 | 0 | 3 |
| HLA-DRB4 | SOX17 | 0.600066 | 4 | 0 | 3 |
| HLA-DRB4 | PROM1 | 0.599028 | 3 | 0 | 3 |
| HLA-DRB4 | ERG | 0.579783 | 4 | 0 | 3 |
| HLA-DRB4 | C9orf40 | 0.577659 | 4 | 0 | 3 |
| HLA-DRB4 | HLA-DMA | 0.57729 | 6 | 0 | 3 |
| HLA-DRB4 | FAS | 0.559604 | 5 | 0 | 3 |
| HLA-DRB4 | HLA-DRA | 0.551762 | 7 | 0 | 4 |
| HLA-DRB4 | IRF4 | 0.534079 | 5 | 0 | 3 |
| HLA-DRB4 | HLA-DPB1 | 0.531134 | 7 | 0 | 3 |
For details and further investigation, click here
