| Full name: Lck interacting transmembrane adaptor 1 | Alias Symbol: FLJ20406|dJ583P15.4|LIME | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 54923 | HGNC ID: HGNC:26016 | Ensembl Gene: ENSG00000203896 | OMIM ID: 609809 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of LIME1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LIME1 | 54923 | 219541_at | 0.2085 | 0.5550 | |
| GSE20347 | LIME1 | 54923 | 219541_at | -0.0018 | 0.9911 | |
| GSE23400 | LIME1 | 54923 | 219541_at | 0.0402 | 0.3422 | |
| GSE26886 | LIME1 | 54923 | 219541_at | 0.2578 | 0.0682 | |
| GSE29001 | LIME1 | 54923 | 219541_at | -0.1228 | 0.4043 | |
| GSE38129 | LIME1 | 54923 | 219541_at | 0.0951 | 0.4188 | |
| GSE45670 | LIME1 | 54923 | 219541_at | -0.0017 | 0.9853 | |
| GSE63941 | LIME1 | 54923 | 219541_at | 0.5753 | 0.0027 | |
| GSE77861 | LIME1 | 54923 | 219541_at | -0.0592 | 0.7739 | |
| GSE97050 | LIME1 | 54923 | A_23_P376088 | 0.2058 | 0.3706 | |
| SRP064894 | LIME1 | 54923 | RNAseq | 0.4202 | 0.2227 | |
| SRP133303 | LIME1 | 54923 | RNAseq | -0.3028 | 0.2394 | |
| SRP159526 | LIME1 | 54923 | RNAseq | -0.2263 | 0.5914 | |
| SRP193095 | LIME1 | 54923 | RNAseq | -0.2703 | 0.2479 | |
| SRP219564 | LIME1 | 54923 | RNAseq | 0.8781 | 0.0408 | |
| TCGA | LIME1 | 54923 | RNAseq | -0.1072 | 0.4934 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LIME1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of LIME1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LIME1 | 54923 | 14 | 2 | 14 | |
| GSE20123 | LIME1 | 54923 | 14 | 2 | 14 | |
| GSE43470 | LIME1 | 54923 | 11 | 1 | 31 | |
| GSE46452 | LIME1 | 54923 | 35 | 0 | 24 | |
| GSE47630 | LIME1 | 54923 | 25 | 1 | 14 | |
| GSE54993 | LIME1 | 54923 | 0 | 17 | 53 | |
| GSE54994 | LIME1 | 54923 | 29 | 0 | 24 | |
| GSE60625 | LIME1 | 54923 | 0 | 0 | 11 | |
| GSE74703 | LIME1 | 54923 | 10 | 0 | 26 | |
| GSE74704 | LIME1 | 54923 | 11 | 0 | 9 | |
| TCGA | LIME1 | 54923 | 44 | 4 | 48 |
Total number of gains: 193; Total number of losses: 27; Total Number of normals: 268.
Somatic mutations of LIME1:
Generating mutation plots.
Highly correlated genes for LIME1:
Showing top 20/359 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LIME1 | ORM1 | 0.785601 | 3 | 0 | 3 |
| LIME1 | PRKCG | 0.784784 | 3 | 0 | 3 |
| LIME1 | SLC22A8 | 0.762401 | 3 | 0 | 3 |
| LIME1 | SALL3 | 0.750372 | 3 | 0 | 3 |
| LIME1 | SEMA3F | 0.745466 | 3 | 0 | 3 |
| LIME1 | SCN5A | 0.733166 | 4 | 0 | 4 |
| LIME1 | KIRREL2 | 0.730264 | 3 | 0 | 3 |
| LIME1 | NXPH3 | 0.721538 | 3 | 0 | 3 |
| LIME1 | CELF3 | 0.71748 | 4 | 0 | 4 |
| LIME1 | PGC | 0.714972 | 4 | 0 | 4 |
| LIME1 | PCSK1N | 0.71249 | 4 | 0 | 3 |
| LIME1 | PNLIPRP1 | 0.709514 | 3 | 0 | 3 |
| LIME1 | IL21 | 0.705756 | 3 | 0 | 3 |
| LIME1 | SIGLEC7 | 0.70498 | 5 | 0 | 4 |
| LIME1 | ABCC8 | 0.704928 | 3 | 0 | 3 |
| LIME1 | NECAB3 | 0.701416 | 4 | 0 | 3 |
| LIME1 | FOXB1 | 0.700962 | 3 | 0 | 3 |
| LIME1 | THPO | 0.696749 | 3 | 0 | 3 |
| LIME1 | SHISA8 | 0.695934 | 4 | 0 | 3 |
| LIME1 | KIR3DL3 | 0.694531 | 4 | 0 | 3 |
For details and further investigation, click here
