| Full name: solute carrier organic anion transporter family member 5A1 | Alias Symbol: OATPRP4|OATP-J|OATP5A1 | ||
| Type: protein-coding gene | Cytoband: 8q13.3 | ||
| Entrez ID: 81796 | HGNC ID: HGNC:19046 | Ensembl Gene: ENSG00000137571 | OMIM ID: 613543 |
| Drug and gene relationship at DGIdb | |||
Expression of SLCO5A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLCO5A1 | 81796 | 230650_at | 0.2683 | 0.5675 | |
| GSE20347 | SLCO5A1 | 81796 | 220984_s_at | -0.0730 | 0.1501 | |
| GSE23400 | SLCO5A1 | 81796 | 220984_s_at | -0.2597 | 0.0000 | |
| GSE26886 | SLCO5A1 | 81796 | 220984_s_at | 0.0370 | 0.8198 | |
| GSE29001 | SLCO5A1 | 81796 | 220984_s_at | -0.2119 | 0.1505 | |
| GSE38129 | SLCO5A1 | 81796 | 220984_s_at | -0.2117 | 0.0011 | |
| GSE45670 | SLCO5A1 | 81796 | 220984_s_at | 0.0715 | 0.4600 | |
| GSE53622 | SLCO5A1 | 81796 | 106706 | 0.5055 | 0.0061 | |
| GSE53624 | SLCO5A1 | 81796 | 106706 | 0.5628 | 0.0001 | |
| GSE63941 | SLCO5A1 | 81796 | 220984_s_at | 0.0129 | 0.9377 | |
| GSE77861 | SLCO5A1 | 81796 | 220984_s_at | -0.0599 | 0.5573 | |
| GSE97050 | SLCO5A1 | 81796 | A_23_P135669 | -0.5557 | 0.3796 | |
| SRP133303 | SLCO5A1 | 81796 | RNAseq | 1.1329 | 0.0020 | |
| SRP159526 | SLCO5A1 | 81796 | RNAseq | 0.9685 | 0.1713 | |
| SRP193095 | SLCO5A1 | 81796 | RNAseq | 0.0792 | 0.7662 | |
| TCGA | SLCO5A1 | 81796 | RNAseq | 0.0310 | 0.9426 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SLCO5A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLCO5A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLCO5A1 | 81796 | 15 | 1 | 14 | |
| GSE20123 | SLCO5A1 | 81796 | 16 | 1 | 13 | |
| GSE43470 | SLCO5A1 | 81796 | 18 | 1 | 24 | |
| GSE46452 | SLCO5A1 | 81796 | 20 | 2 | 37 | |
| GSE47630 | SLCO5A1 | 81796 | 23 | 1 | 16 | |
| GSE54993 | SLCO5A1 | 81796 | 0 | 19 | 51 | |
| GSE54994 | SLCO5A1 | 81796 | 30 | 0 | 23 | |
| GSE60625 | SLCO5A1 | 81796 | 0 | 4 | 7 | |
| GSE74703 | SLCO5A1 | 81796 | 15 | 1 | 20 | |
| GSE74704 | SLCO5A1 | 81796 | 11 | 0 | 9 | |
| TCGA | SLCO5A1 | 81796 | 51 | 2 | 43 |
Total number of gains: 199; Total number of losses: 32; Total Number of normals: 257.
Somatic mutations of SLCO5A1:
Generating mutation plots.
Highly correlated genes for SLCO5A1:
Showing top 20/322 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLCO5A1 | RNF122 | 0.74333 | 3 | 0 | 3 |
| SLCO5A1 | USP2 | 0.731328 | 3 | 0 | 3 |
| SLCO5A1 | RIT2 | 0.708026 | 3 | 0 | 3 |
| SLCO5A1 | JAK3 | 0.704921 | 3 | 0 | 3 |
| SLCO5A1 | DUSP21 | 0.694115 | 3 | 0 | 3 |
| SLCO5A1 | PTP4A3 | 0.682626 | 3 | 0 | 3 |
| SLCO5A1 | ARHGAP44 | 0.682286 | 3 | 0 | 3 |
| SLCO5A1 | PLA2G5 | 0.667672 | 5 | 0 | 5 |
| SLCO5A1 | ZNF717 | 0.665398 | 3 | 0 | 3 |
| SLCO5A1 | CT55 | 0.662651 | 3 | 0 | 3 |
| SLCO5A1 | CDK20 | 0.66005 | 5 | 0 | 3 |
| SLCO5A1 | SLC17A7 | 0.65982 | 5 | 0 | 4 |
| SLCO5A1 | HOXB1 | 0.656559 | 3 | 0 | 3 |
| SLCO5A1 | EPM2A | 0.652213 | 3 | 0 | 3 |
| SLCO5A1 | COX6A2 | 0.651945 | 3 | 0 | 3 |
| SLCO5A1 | CCDC30 | 0.649206 | 4 | 0 | 3 |
| SLCO5A1 | GRPR | 0.648225 | 6 | 0 | 5 |
| SLCO5A1 | ZC4H2 | 0.647978 | 3 | 0 | 3 |
| SLCO5A1 | TRAF5 | 0.644179 | 4 | 0 | 3 |
| SLCO5A1 | CSH1 | 0.644125 | 5 | 0 | 4 |
For details and further investigation, click here
