| Full name: CDC42 effector protein 1 | Alias Symbol: MSE55|CEP1|Borg5 | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 11135 | HGNC ID: HGNC:17014 | Ensembl Gene: ENSG00000128283 | OMIM ID: 606084 |
| Drug and gene relationship at DGIdb | |||
Expression of CDC42EP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDC42EP1 | 11135 | 204693_at | 0.3737 | 0.3802 | |
| GSE20347 | CDC42EP1 | 11135 | 204693_at | -0.2416 | 0.3255 | |
| GSE23400 | CDC42EP1 | 11135 | 204693_at | -0.2088 | 0.0024 | |
| GSE26886 | CDC42EP1 | 11135 | 204693_at | 0.2118 | 0.1525 | |
| GSE29001 | CDC42EP1 | 11135 | 204693_at | -0.2488 | 0.0605 | |
| GSE38129 | CDC42EP1 | 11135 | 204693_at | -0.2405 | 0.2358 | |
| GSE45670 | CDC42EP1 | 11135 | 204693_at | 0.1798 | 0.1251 | |
| GSE53622 | CDC42EP1 | 11135 | 16241 | -0.2977 | 0.0383 | |
| GSE53624 | CDC42EP1 | 11135 | 16241 | -0.2320 | 0.0121 | |
| GSE63941 | CDC42EP1 | 11135 | 204693_at | 0.8301 | 0.0966 | |
| GSE77861 | CDC42EP1 | 11135 | 204693_at | -0.1374 | 0.5896 | |
| GSE97050 | CDC42EP1 | 11135 | A_33_P3407424 | 0.1384 | 0.5839 | |
| SRP007169 | CDC42EP1 | 11135 | RNAseq | -1.2868 | 0.0027 | |
| SRP008496 | CDC42EP1 | 11135 | RNAseq | -1.5706 | 0.0000 | |
| SRP064894 | CDC42EP1 | 11135 | RNAseq | -0.4616 | 0.1613 | |
| SRP133303 | CDC42EP1 | 11135 | RNAseq | -0.3073 | 0.1432 | |
| SRP159526 | CDC42EP1 | 11135 | RNAseq | -0.8881 | 0.0030 | |
| SRP193095 | CDC42EP1 | 11135 | RNAseq | -0.0905 | 0.6700 | |
| SRP219564 | CDC42EP1 | 11135 | RNAseq | -0.7825 | 0.0711 | |
| TCGA | CDC42EP1 | 11135 | RNAseq | -0.2237 | 0.0009 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CDC42EP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDC42EP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDC42EP1 | 11135 | 6 | 5 | 19 | |
| GSE20123 | CDC42EP1 | 11135 | 6 | 4 | 20 | |
| GSE43470 | CDC42EP1 | 11135 | 4 | 6 | 33 | |
| GSE46452 | CDC42EP1 | 11135 | 32 | 2 | 25 | |
| GSE47630 | CDC42EP1 | 11135 | 9 | 4 | 27 | |
| GSE54993 | CDC42EP1 | 11135 | 3 | 6 | 61 | |
| GSE54994 | CDC42EP1 | 11135 | 9 | 8 | 36 | |
| GSE60625 | CDC42EP1 | 11135 | 5 | 0 | 6 | |
| GSE74703 | CDC42EP1 | 11135 | 4 | 4 | 28 | |
| GSE74704 | CDC42EP1 | 11135 | 3 | 2 | 15 | |
| TCGA | CDC42EP1 | 11135 | 27 | 15 | 54 |
Total number of gains: 108; Total number of losses: 56; Total Number of normals: 324.
Somatic mutations of CDC42EP1:
Generating mutation plots.
Highly correlated genes for CDC42EP1:
Showing top 20/400 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDC42EP1 | FKBP4 | 0.783524 | 3 | 0 | 3 |
| CDC42EP1 | TCF19 | 0.782888 | 3 | 0 | 3 |
| CDC42EP1 | CCDC7 | 0.782783 | 3 | 0 | 3 |
| CDC42EP1 | SUMO3 | 0.755928 | 3 | 0 | 3 |
| CDC42EP1 | PUSL1 | 0.753019 | 3 | 0 | 3 |
| CDC42EP1 | NUP188 | 0.752561 | 3 | 0 | 3 |
| CDC42EP1 | NPLOC4 | 0.751934 | 3 | 0 | 3 |
| CDC42EP1 | P2RY13 | 0.738469 | 3 | 0 | 3 |
| CDC42EP1 | STAC | 0.738102 | 3 | 0 | 3 |
| CDC42EP1 | MRPL51 | 0.737499 | 3 | 0 | 3 |
| CDC42EP1 | NCLN | 0.731861 | 3 | 0 | 3 |
| CDC42EP1 | UBA1 | 0.72089 | 4 | 0 | 4 |
| CDC42EP1 | ESR2 | 0.718481 | 3 | 0 | 3 |
| CDC42EP1 | PWWP2A | 0.71836 | 3 | 0 | 3 |
| CDC42EP1 | HSD3B7 | 0.715369 | 3 | 0 | 3 |
| CDC42EP1 | OS9 | 0.711859 | 4 | 0 | 3 |
| CDC42EP1 | KRI1 | 0.708153 | 3 | 0 | 3 |
| CDC42EP1 | CMIP | 0.704905 | 4 | 0 | 3 |
| CDC42EP1 | TBC1D25 | 0.704892 | 3 | 0 | 3 |
| CDC42EP1 | ANKRD54 | 0.698096 | 4 | 0 | 3 |
For details and further investigation, click here
