| Full name: homeobox C5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 3222 | HGNC ID: HGNC:5127 | Ensembl Gene: ENSG00000172789 | OMIM ID: 142973 |
| Drug and gene relationship at DGIdb | |||
Expression of HOXC5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HOXC5 | 3222 | 206739_at | -0.1047 | 0.5495 | |
| GSE20347 | HOXC5 | 3222 | 206739_at | -0.0781 | 0.4773 | |
| GSE23400 | HOXC5 | 3222 | 206739_at | -0.1119 | 0.0016 | |
| GSE26886 | HOXC5 | 3222 | 206739_at | -0.1531 | 0.1116 | |
| GSE29001 | HOXC5 | 3222 | 206739_at | -0.1412 | 0.2722 | |
| GSE38129 | HOXC5 | 3222 | 206739_at | -0.2130 | 0.0083 | |
| GSE45670 | HOXC5 | 3222 | 206739_at | 0.0176 | 0.8698 | |
| GSE53622 | HOXC5 | 3222 | 50612 | 0.3347 | 0.0018 | |
| GSE53624 | HOXC5 | 3222 | 50612 | 0.7091 | 0.0000 | |
| GSE63941 | HOXC5 | 3222 | 206739_at | 0.1342 | 0.6203 | |
| GSE77861 | HOXC5 | 3222 | 206739_at | -0.2175 | 0.2726 | |
| GSE97050 | HOXC5 | 3222 | A_23_P162355 | -0.2068 | 0.7333 | |
| SRP133303 | HOXC5 | 3222 | RNAseq | 0.6331 | 0.1175 | |
| SRP159526 | HOXC5 | 3222 | RNAseq | 1.2014 | 0.0496 | |
| SRP219564 | HOXC5 | 3222 | RNAseq | -0.3798 | 0.5864 | |
| TCGA | HOXC5 | 3222 | RNAseq | -0.5495 | 0.0014 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by HOXC5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HOXC5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HOXC5 | 3222 | 4 | 1 | 25 | |
| GSE20123 | HOXC5 | 3222 | 4 | 1 | 25 | |
| GSE43470 | HOXC5 | 3222 | 3 | 0 | 40 | |
| GSE46452 | HOXC5 | 3222 | 7 | 1 | 51 | |
| GSE47630 | HOXC5 | 3222 | 10 | 2 | 28 | |
| GSE54993 | HOXC5 | 3222 | 0 | 5 | 65 | |
| GSE54994 | HOXC5 | 3222 | 4 | 1 | 48 | |
| GSE60625 | HOXC5 | 3222 | 0 | 0 | 11 | |
| GSE74703 | HOXC5 | 3222 | 3 | 0 | 33 | |
| GSE74704 | HOXC5 | 3222 | 3 | 1 | 16 | |
| TCGA | HOXC5 | 3222 | 15 | 11 | 70 |
Total number of gains: 53; Total number of losses: 23; Total Number of normals: 412.
Somatic mutations of HOXC5:
Generating mutation plots.
Highly correlated genes for HOXC5:
Showing top 20/393 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HOXC5 | CNTF | 0.759811 | 3 | 0 | 3 |
| HOXC5 | UBE2D2 | 0.731499 | 3 | 0 | 3 |
| HOXC5 | GSTT2 | 0.728739 | 3 | 0 | 3 |
| HOXC5 | PGM1 | 0.724979 | 3 | 0 | 3 |
| HOXC5 | PPP3CC | 0.722901 | 3 | 0 | 3 |
| HOXC5 | THRB | 0.719971 | 4 | 0 | 4 |
| HOXC5 | PCBP3 | 0.714965 | 4 | 0 | 3 |
| HOXC5 | AP4E1 | 0.706381 | 3 | 0 | 3 |
| HOXC5 | LIMS2 | 0.704567 | 3 | 0 | 3 |
| HOXC5 | GRPR | 0.683081 | 3 | 0 | 3 |
| HOXC5 | KIAA1191 | 0.681941 | 3 | 0 | 3 |
| HOXC5 | ZFC3H1 | 0.6701 | 3 | 0 | 3 |
| HOXC5 | APOL5 | 0.667064 | 3 | 0 | 3 |
| HOXC5 | INCENP | 0.664679 | 4 | 0 | 4 |
| HOXC5 | NRSN2 | 0.663243 | 4 | 0 | 4 |
| HOXC5 | GABRA1 | 0.662845 | 3 | 0 | 3 |
| HOXC5 | PWWP2A | 0.661608 | 5 | 0 | 4 |
| HOXC5 | APC | 0.660624 | 4 | 0 | 3 |
| HOXC5 | HOXA3 | 0.66031 | 5 | 0 | 5 |
| HOXC5 | LINC00557 | 0.658221 | 3 | 0 | 3 |
For details and further investigation, click here
